Inflammatory Cardiomyopathy (DCMi) - Pathogenesis and Therapy PDF Download

Author: Heinz-Peter Schultheiss
Publisher: Springer Science & Business Media
ISBN: 3764383526
Category : Medical
Languages : en
Pages : 295

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Book Description
Cardiomyopathy is one of the most frequent causes of heart failure. It is often associated with inadequate heart pumping or other heart function abnormalities. There are many different causes of the disease, therefore many different kinds of cardiomyopathies exist. This volume, written by a leading expert, focuses on inflammatory CM, belonging to the Dilated Cardiomyopathies (DCMi). It covers epidemiology/prognosis, pathology, immunology, diagnosis and treatment strategies.

Author: Heinz-Peter Schultheiss
Publisher:
ISBN: 9783764394189
Category :
Languages : en
Pages : 310

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Book Description

Author: Chūichi Kawai
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 330

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Book Description

Author: Heinz-Peter Schultheiss
Publisher: Springer Science & Business Media
ISBN: 3540308229
Category : Medical
Languages : en
Pages : 369

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Book Description
The interconnectedness of genetics and susceptibility to disease, viral and non-viral inflammation, and the role of immunity and the development of autoimmunity is a fascinating and much discussed topic in cardiomyopathy. This publication constitutes the outcome of an ESRF meeting held together with the German Research Foundation. Clinical researchers, immunologists, virologists and molecular biologists provide the latest findings in their fields, advancing our understanding of what causes chronic viral and inflammatory cardiomyopathy, why it affects a subset of individuals while sparing the majority, how we can develop better therapies, and whether the disease can be prevented. Special emphasis is placed on the role of viruses in the aetiology and pathogenesis of cardiomyopathy. The editors are convinced that the broad spectrum covered by this state-of-the-art publication will be of exceptional value to its readers.

Author: Alida L. P. Caforio
Publisher: Springer
ISBN: 9783030352783
Category : Medical
Languages : en
Pages : 0

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Book Description
This book is an up-to-date, comprehensive, clinically oriented guide to the diagnosis and treatment of patients with myocarditis. The opening chapters address the classification, histopathology and molecular diagnosis, as well as the polymorphic clinical presentations, ranging from myocardial infarction with normal coronary arteries; arrhythmias of variable type and clinical severity and fulminant, acute, sub-acute or chronic heart failure; to life-threatening unexplained cardiogenic shock and sudden cardiac death. Including chapters from leading International experts in the field, it covers all key issues from bench to bedside. Topics presented include epidemiology, etiology, pathogenesis, clinical and diagnostic work-up, the role of endomyocardial biopsy and of non-invasive cardiac imaging, risk stratification, and cardiological and etiology-specific management and follow-up. For each topic, a comprehensive review of the current literature is provided and practical suggestions are offered for short- and long-term management. Lastly, future perspectives and gaps in the current knowledge are also addressed. The book also covers a key discovery of last the 2 decades, namely the autoimmune origin of myocarditis in a sizable proportion of patients, discussing in detail the role of immunosuppression and immunomodulation, as well as the need for a multidisciplinary approach to the disease. Mainly intended for cardiologists, general physicians, clinical immunologists and rheumatologists, it is also a valuable tool for residents in Cardiology, Internal Medicine, Clinical Immunology and Rheumatology.

Author: Jose Milei
Publisher: BoD – Books on Demand
ISBN: 9535110829
Category : Medical
Languages : en
Pages : 210

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Book Description
Myocarditis is a clinical syndrome, most frequently of infectious etiology, that occurs with a broad range of relatively non-specific symptoms, and consists of an inflammatory process of the heart with necrosis and degeneration of the myocardium by inflammatory infiltration of immune cells. The infection can cause direct injury of cardiomyocytes as well as immune-mediated destruction of the myocardium, leading to cardiac dysfunction. In this book, the broad aspects of myocarditis are fully presented by leading international experts. The texts are devoted to both clinical aspects and pathophysiology, and they present comprehensive reviews of the causes of myocarditis, its classification, diagnosis, and treatment, as well as myocarditis in special populations such as pediatric, peripartum and chronic chagasic myocarditis.

Author: Gianfranco Sinagra
Publisher: Springer
ISBN: 303013864X
Category : Medical
Languages : en
Pages : 241

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Book Description
This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up. Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice. Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease.

Author: Hanjoerg Just
Publisher: Springer
ISBN: 9783540116172
Category : Medical
Languages : en
Pages : 318

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Book Description
Primary myocardial disease, nowadays referred to as congestive or, more re cently, dilating cardiomyopathy, comprises disorders of varied etiology. Most oftenly the pathogenetic mechanism or causative agent remains unknown. The significance of inflammatory processes, i.e. myocarditis in a wider sense as the etiologic factor has been debated for many years. In a few instances, especially in children and newborns viral infections can be incriminated. In adults this etiology can be ascertained only in rare instances. And it has remained entirely uncertain if, or under which circumstances, and how often virus myocarditis can lead to a chronic disorder of the heart, namely dilated cardiomyopathy. Although it would seem conceivable that an immunological response to an infectious agent might induce parenchymal damage with subsequent loss of cellular function and structural integrity of permanent nature, i.e. dilatation, functional deterioration and dysrhythmias, numerous attempts to establish such a pathogenetic mechanism have not yet furnished convinicing results. Therefore the reader will direct his attention specifically to the respective contribution in this volume. Morphologic studies have yielded a host of new and intriguing findings in cardiomyopathy, but have likewise failed to settle the basic question as to which etiology can be held responsible in a given case, especially if an inflam matory process can be incriminated. Specific processes such as sarcoidosis of the heart undoubtedly furnish examples of chronic inflammation as a cause of dilating cardiomyopathy. This disorder, however, as a specific inflammato ry myocardial affection, i.e. myocarditis, is encountered only infrequently.

Author: Gianfranco Sinagra
Publisher: Springer Science & Business Media
ISBN: 8847027578
Category : Medical
Languages : en
Pages : 170

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Book Description
In the last decade, genetics has been emerging as a primary issue in the diagnosis and management of cardiomyopathies. This book is intended to be a state-of-the-art monograph on these diseases, describing their genetic causes, defining the molecular basis and presenting extensive descriptions of genotype–phenotype correlations. Other chapters are focused on the role of clinical observation, on ECG and echocardiography. With its highlight on the most recent discoveries in the field of molecular genetics as well as on the correct clinical approach to patients with heart muscle disease, the book is aimed at physicians and clinical cardiologists with a particular interest in myocardial diseases and in their genetic causes.

Author: Gretchen G. Kimmick
Publisher:
ISBN: 9783319430959
Category : Heart
Languages : en
Pages :

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Book Description
Co-edited and written by an interdisciplinary team of experts in oncology and cardiology, this book is a clinically useful resource on these overlapping topics: " Cardiac complications in patients receiving cancer therapy " The treatment of cancer in patients with cardiovascular disease " The treatment of cardiovascular disease in patients with cancer When relevant to medical practice, epidemiology and basic science are also included in the discussion and each chapter is written by an oncologist and a cardiologist. Additionally, the chapters follow a similar format to make the book truly interdisciplinary, user-friendly, and clinically applicable to specialists and non-specialists who care for patients with both cancer and cardiovascular disease.