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Author: National Research Council Publisher: National Academies Press ISBN: 0309316553 Category : Science Languages : en Pages : 158
Book Description
The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.
Author: National Research Council Publisher: National Academies Press ISBN: 0309316553 Category : Science Languages : en Pages : 158
Book Description
The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.
Author: Christoph Wittmann Publisher: John Wiley & Sons ISBN: 3527341811 Category : Science Languages : en Pages : 642
Book Description
The latest volume in the Advanced Biotechnology series provides an overview of the main product classes and platform chemicals produced by biotechnological processes today, with applications in the food, healthcare and fine chemical industries. Alongside the production of drugs and flavors as well as amino acids, bio-based monomers and polymers and biofuels, basic insights are also given as to the biotechnological processes yielding such products and how large-scale production may be enabled and improved. Of interest to biotechnologists, bio and chemical engineers, as well as those working in the biotechnological, chemical, and food industries.
Author: Magnus Fröhling Publisher: Springer Nature ISBN: 3030470660 Category : Science Languages : en Pages : 363
Book Description
This book reviews the assessment of industrial biotechnology products and processes from a sustainable perspective. Industrial Biotechnology is a comparably young field which comes along with high expectations with regard to sustainability issues. These stem from the promise of reducing greenhouse gas emissions and replacing fossil resources in the near or later future and using green technology, i.e. more environmentally friendly technologies. The intended economic, ecological and social benefits, however, need to be proven, resulting in a variety of challenges, both from a methodological and application point of view. In this book, specific assessment and application topics of industrial biotechnology are addressed, highlighting challenges and solutions for both developers and users of assessment methods. In twelve chapters, experts in their particular fields define the scope, characterize industrial biotechnology and show in their contributions the state of the art, challenges and prospects of assessing industrial biotechnology products and processes. The chapter 'Societal and Ethical Aspects of Industrial Biotechnology' of this book is available open access under a CC BY 4.0 license at link.springer.com
Author: P. Hambleton Publisher: Springer Science & Business Media ISBN: 9401113521 Category : Science Languages : en Pages : 317
Book Description
As an industry, biotechnology may be likened to the Hymn Book, being both ancient and modern. Whereas activities such as baking, brewing, the fermenting of foods date from our earliest attempts to control and utilise the environment, the application of recombinant DNA technology is recognised as being at the forefront of novel industrial development. Perhaps because of its association with processing foodstuffs together with the benefits derived from applications in the early organic chemistry and pharmaceutical industries, biotechnology has been regarded as being inherently safe. Yet unlike other modern industries, such as chemical and nuclear, where regulation has followed from incidents or accidents, modern biotechnology has been subject to close scrutiny and regulation almost from its inception. The process of regulation itself is somewhat unusual in that it was initially self-imposed by the very scientists who developed the fundamental techniques of recombinant DNA technology. They recognised the signific ance of their development but were concerned of the effects on humans and the environment of uncontrolled application of the new, powerful technology. Concern about the possible consequences of genetic manipula tion has undoubtedly been the driving force behind the regulations that are now in place in many parts of the world and which are the subject of this book. Safety issues in the biotechnology industry can be categorised under three headings: worker, environmental and consumer (product) safety.
Author: Devarajan Thangadurai Publisher: CRC Press ISBN: 177188262X Category : Medical Languages : en Pages : 485
Book Description
This important new book covers recent advancements, innovations, and technologies in industrial biotechnology, specifically addressing the application of various biomolecules in industrial production and in cleaning and environmental remediation sectors. The goal of industrial biotechnology is to develop new techniques and technologies to transform renewable raw materials into chemicals, materials, and fuels by the substitution of fossil fuels. With the increase in the world’s population and the resultant growing energy demand, the need for more energy can be successfully met with the advancements in industrial biotechnology. Currently across the globe significant research has been undertaken in the production of cleaner fuels, materials, and semi-synthetic chemicals, with environmental benefits. Developing countries have huge agricultural resources that could be utilized for production of value-added byproducts for the sustainable development of bio-based economy. The book opens with the chapter on the production of exopolysaccharides from halophilic microorganisms, a polymer that is normally very useful in various production sectors of the food, pharmaceutical, and petroleum industries. The book goes on to cover: The production of antimicrobial compounds from alkaliphilic bacteria Thermophilic actinomycetes Food, agro, and pharmaceutical potential and biotechnological applications of biosurfactants, halophiles, cyclodextrin glycosyl transferease, fungal chitinase, proteases, yeasts and yeast products Also covered in the book are the environmental aspects of industrial biotechnology such as the genetic enhancement for biofuel production, the production of biodegradable thermoplastics, advancements in the synthesis of bio-oil, ecofriendly treatment of agro-based lignocelluloses, and anaerobic bio reactors for hydrocarbon remediation. The international roster of chapter authors have been chosen for their renowned expertise and contribution to the various fields of industrial biotechnology. This book is suitable to chemists, biotechnologists from research institutes, academia, and students as well as for industry professionals
Author: Donald L. Drakeman Publisher: Oxford University Press ISBN: 0195084004 Category : Biotechnology industries Languages : en Pages : 241
Book Description
"Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. How could a large collection of small companies, most with fewer than 50 employees, compete in one of the world's most breathtakingly expensive and highly regulated industries? This book shows how biotech companies have met the challenge by creating nearly 40% more of the most important treatments for unmet medical needs. Moreover, they have done so with much lower overall costs. The book focuses on both the companies themselves and the broader biotech ecosystem that supports them. Its portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies shows how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions. Looking to the future, it concludes that biomedical research will continue to be most effective in the hands of a large group of small companies as long as national healthcare policies allow the rest of the ecosystem to continue to thrive"--
Author: OECD Publisher: OECD Publishing ISBN: 9264126635 Category : Languages : en Pages : 142
Book Description
This publication examines the international drivers, the enabling technologies that are fast-tracking Industrial Biotechnology, industry trends, some of the products that are appearing on the market, industry structure and finance, and finally policy measures and trends.
Author: Wilfred Cote Publisher: Springer Science & Business Media ISBN: 1475708335 Category : Science Languages : en Pages : 720
Book Description
This proceedings volume represents the culmination of nearly three years of planning, organizing and carrying out of a NATO Ad vanced Study Institute on Biomass Utilization. The effort was initi ated by Dr. Harry Sobel, then Editor of Biosources Digest, and a steering committee representing the many disciplines that this field brings together. . When the fiscal and logistical details of the original plan could not be worked out, the idea was temporarily suspended. In the spring of 1982, the Renewable Materials Institute of the State University of New York at the College of Environmental Science and Forestry in Syracuse, New York revived the plan. A number of modifications had to be made, including the venue which was changed from the U.S.A. to Portugal. Additional funding beyond the basic support provided by the Scientific Affairs Division of NATO had to be obtained. Ul timately there were supplementary grants from the Foundation for Microbiology and the Anne S. Richardson Fund to assist student participants. The New York State College of Forestry Foundation, Inc. provided major support through the Renewable Ma terials Institute. The ASI was held in Alcabideche, Portugal from September 26 to October 9, 1982. Eighty participants including fifteen principal lecturers were assembled at the Hotel Sintra Estoril for the program that was organized as a comprehensive course on biomass utilization. The main lectures were supplemented by relevant short papers offered by the participants.
Author: National Academies of Sciences, Engineering, and Medicine Publisher: National Academies Press ISBN: 0309452058 Category : Science Languages : en Pages : 231
Book Description
Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.
Author: National Research Council
Author: National Research Council
Author: Christoph Wittmann
Author: Magnus Fröhling
Author: Vittorio Chiesa
Author: P. Hambleton
Author: Devarajan Thangadurai
Author: Donald L. Drakeman
Author: OECD
Author: Wilfred Cote
Author: National Academies of Sciences, Engineering, and Medicine