Author: J. Michael Lord Publisher: Springer Science & Business Media ISBN: 3642121764 Category : Science Languages : en Pages : 275
Book Description
Many plants produce enzymes collectively known as ribosome-inactivating proteins (RIPs). RIPs catalyze the removal of an adenine residue from a conserved loop in the large ribosomal RNA. The adenine residue removed by this depurination is crucial for the binding of elongation factors. Ribosomes modified in this way are no longer able to carry out protein synthesis. Most RIPs exist as single polypeptides (Type 1 RIPs) which are largely non-toxic to mammalian cells because they are unable to enter them and thus cannot reach their ribosomal substrate. In some instances, however, the RIP forms part of a heterodimer where its partner polypeptide is a lectin (Type 2 RIPs). These heterodimeric RIPs are able to bind to and enter mammalian cells. Their ability to reach and modify ribosomes in target cells means these proteins are some of the most potently cytotoxic poisons found in nature, and are widely assumed to play a protective role as part of the host plant’s defenses. RIPs are able to further damage target cells by inducing apoptosis. In addition, certain plants produce lectins lacking an RIP component but which are also cytotoxic. This book focuses on the structure/function and some potential applications of these toxic plant proteins.
Author: M.R. El-Gewely Publisher: Elsevier ISBN: 0080877338 Category : Science Languages : en Pages : 525
Book Description
The Biotechnology Annual Review series aims at covering developments in the field of biotechnology in the form of comprehensive, illustrated and well-referenced reviews. Recent expansion in this field, both industrial and educational, along with the increase in the number of new journals reporting new results, has greatly increased the need for exactly this type of series, continuously providing reviews. Every volume, published yearly, will cover a different aspect of biotechnology. The "Editorial Board" of Biotechnology Annual Review encourages suggestions and contributions of articles from industry or from academic institutions that would constitute a comprehensive covering of a relevant topic in biotechnology.Proposals for contributions and/or suggestions for topics for future volumes in this series should be sent to the Editor: Professor M.R. El-GewelyDepartment of biotechnologyUniversity of TromsøIMB, MH-ByggetN-9037 TromsøNorwayTel: (+47) 77 644654Fax: (+47) 77 645350
Author: Susan G. Wynn Publisher: Elsevier Health Sciences ISBN: 0323029981 Category : Medical Languages : en Pages : 736
Book Description
This full-color reference offers practical, evidence-based guidance on using more than 120 medicinal plants, including how to formulate herbal remedies to treat common disease conditions. A body-systems based review explores herbal medicine in context, offering information on toxicology, drug interactions, quality control, and other key topics. More than 120 herbal monographs provide quick access to information on the historical use of the herb in humans and animals, supporting studies, and dosing information. Includes special dosing, pharmacokinetics, and regulatory considerations when using herbs for horses and farm animals. Expanded pharmacology and toxicology chapters provide thorough information on the chemical basis of herbal medicine. Explores the evolutionary relationship between plants and mammals, which is the basis for understanding the unique physiologic effects of herbs. Includes a body systems review of herbal remedies for common disease conditions in both large and small animals. Discusses special considerations for the scientific research of herbs, including complex and individualized interventions that may require special design and nontraditional outcome goals.
Author: Roberto Fritsche-Neto Publisher: Springer Science & Business Media ISBN: 3642330878 Category : Science Languages : en Pages : 166
Book Description
Experience shows that biotic stresses occur with different levels of intensity in nearly all agricultural areas around the world. The occurrence of insects, weeds and diseases caused by fungi, bacteria or viruses may not be relevant in a specific year but they usually harm yield in most years. Global warming has shifted the paradigm of biotic stresses in most growing areas, especially in the tropical countries, sparking intense discussions in scientific forums. This book was written with the idea of collecting in a single publication the most recent advances and discoveries concerning breeding for biotic stresses, covering all major classes of biotic challenges to agriculture and food production. Accordingly, it presents the state-of-the-art in plant stresses caused by all microorganisms, weeds and insects and how to breed for them. Complementing Plant Breeding for Abiotic Stress Tolerance, this book was written for scientists and students interested in learning how to breed for biotic stress scenarios, allowing them to develop a greater understanding of the basic mechanisms of resistance to biotic stresses and develop resistant cultivars.
Author: J. Michael Lord
Author: Meyer Chessin
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Author: M.R. El-Gewely
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Author: Susan G. Wynn
Author: Roberto Fritsche-Neto
Author: American Society for Virology. Meeting
Author: P. Gopalakrishnakone