Immunomodulation with Immunoglobulins for Autoimmune Diseases and Infections PDF Download

Author: Michael Georg Kiehl
Publisher: Thieme
ISBN: 9781588900784
Category : Medical
Languages : en
Pages : 164

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Book Description
The multiple possibilities for use of polyvalent immunoglobulins in autoimmune diseases, for prophylaxis and therapy for infections, including sepsis with immune paralysis, are remarkable. In 23 contributions specialist authors present: The immunomodulatory action of i.v. immunoglobulins for autoimmune diseases and infections The possible mechanisms of action of polyvalent immunoglobulins The broad spectrum of beneficial use of immunoglobulins in widely differing clinical disciplines

Author: A. Morell
Publisher: CRC Press
ISBN: 9781850705109
Category : Medical
Languages : en
Pages : 248

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Book Description
This work provides a comprehensive review of the role of intravenous immunoglobulins in a wide range of immune-related diseases. Over 20 research workers from America and Europe together examine many important aspects of this subject and, in particular, assess the role of immunoglobulins in the treatment of asthma and allergy, autoimmune disorders, juvenile arthritis and recurrent pregnancy loss.

Author: National Research Council
Publisher: National Academies Press
ISBN: 0309180686
Category : Medical
Languages : en
Pages : 102

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Book Description
Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

Author: M.D. Kazatchkine
Publisher: CRC Press
ISBN: 9781850706472
Category : Antibody diversity
Languages : en
Pages : 80

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Book Description
This is a high-level technical reference text on new and developing uses of intravenous immunoglobulin (IVIg), virological safety and other treatment issues, and active areas of relevant clinical and basic investigation. Volume editor Kazatchkine explains the importance of this work in his Foreword: IVIg therapy represents the first-line treatment in humoral immunodeficiencies. It also stands as an alternative or complementary approach to targeted immunointervention for immunomodulation of hypersensitivity states and autoimmune diseases. Thus, normal circulating immunoglobulins are now known to play an important role in the selection of immune repertoires and regulation of immune homeostasis, in addition to their role in host defense against infection.

Author: R.C. Kennedy
Publisher: Elsevier
ISBN: 0080534430
Category : Medical
Languages : en
Pages : 557

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Book Description
This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.

Author: Paul Imbach
Publisher: Springer
ISBN: 3319680382
Category : Medical
Languages : en
Pages : 361

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Book Description
This practical manual, written by well-known experts, reviews current indications for the use of IgG concentrates and some other modern immunomodulators and provides fundamental information on present-day immunomodulation in patients (and mice). The book opens by tracing the transition from IgG substitution to IgG immunomodulation and providing expert updates on immunomodulatory indications in autoimmune and inflammatory disorders, including hematologic, neurologic, dermatologic, and other diseases. Basic aspects of IgG concentrates, including methods of production, safety, currently available products, and mechanisms of action, are then discussed. An entire chapter is devoted to the different aspects of immunomodulatory IgG treatment in the bleeding disorder immune thrombocytopenia (ITP). Finally, the transition from polyclonal to monoclonal antibody (mAb) treatment is addressed in detail, covering mAb development, methods, mechanisms of action, adverse effects, and more. Particular attention is paid to the example of anti-CD20 (B-cell) antibody.

Author: Rajesh K. Kesharwani
Publisher: Springer Nature
ISBN: 9811663793
Category : Medical
Languages : en
Pages : 513

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Book Description
This book focuses on a broad range of immunomodulators, including both natural and synthetic ones. It highlights their role in human health. The book discusses nanotechnology-based immunomodulators with special emphasis on different types of formulation to boost the immune system. It highlights the role of immunomodulators against different microbes. This book describes important topics such as Classification and uses of various immunomodulators; Potential role of herbs and spices on immune system; Immune booster activity of prebiotics; Recent advances of nutraceutical and functional foods in Immune health; Antioxidants and immunomodulation; Nanotechnology and immunomodulators in cancer; Immunomodulatory role for the treatment and management of tuberculosis; Immunomodulation in autoimmune disorders; Herbal immunomodulators and COVID-19; Role of Cytokines as Immunomodulators and Immunomodulatory effects of endocrine disrupting chemicals. This book covers various aspects of product innovation, development, and launching of nutritional and pharmaceutical products with reference to immunomodulators. This book is meant for researchers and students in the field of immunology and pharmaceutical sciences.

Author: Sylvie Hermouet
Publisher: Frontiers Media SA
ISBN: 288966046X
Category : Medical
Languages : en
Pages : 171

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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author: Zhifeng Gu
Publisher: Frontiers Media SA
ISBN: 2889746283
Category : Medical
Languages : en
Pages : 144

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Book Description
Dr. Kuo is the Head of Global Business Development at Predicine. The other Topic Editor declares no competing interest with regards to the Research Topic theme.

Author: David Evered
Publisher: John Wiley & Sons
ISBN: 0470513497
Category : Medical
Languages : en
Pages : 288

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Book Description
This work focuses on the autoimmune processes that have now been proven to underlie a number of serious diseases, including diabetes mellitus, rheumatoid arthritis and multiple sclerosis. Papers explore the rapidly expanding developments in research on immune response and regulation, and their potential in the development of treatments for autoimmune diseases. The wide range of subjects covered here include: the nature of intracellular and cell surface-derived ``self'' antigens; competing theories of the generation of immune tolerance and their implications of current theories for research and treatment; possible links between autoimmunity and genetic complement deficiency; the contributions of interferons and class II HLA antigen expression to autoimmunity; and the potential of monoclonal antibodies and other biotechnological advances in treating human autoimmune conditions.