Author: Medical Research Council (Great Britain). Institute for Environment and HealthPublisher:
ISBN:
Category : Air
Languages : en
Pages : 124
Book Description
IEH Report on the Use of Biomarkers in Environmental Exposure Assessment
Author: Medical Research Council (Great Britain). Institute for Environment and HealthPublisher:
ISBN:
Category : Air
Languages : en
Pages : 124
Book Description
The Use of Biomarkers in Environmental Exposure Assessment
Author: Use of Biomarkers in Assessing Health and Environmental Impacts of Chemical Pollutants
Author: Curtis C. TravisPublisher: Springer Science & Business Media
ISBN: 1489920528
Category : Medical
Languages : en
Pages : 283
Book Description
Biological markers (biomarkers) are useful tools for understanding the nature and extent of human exposure and risk from environmental toxicants. Biomarkers are classified into three basic categories: exposure, effect, or susceptibility. A marker of exposure is the product of the interaction between a target cell or molecule and a foreign substance (NAS, 1989). These markers can be used to determine the biologically effective dose necessary to elicit a particular physiological change in an organism. A marker of effect is a biochemical or physiological change in an organism that can predict the onset of adverse health effects resulting from a given exposure. Lastly, markers of susceptibility act as indicators of an inherent or acquired tendency of an organism to experience an adverse health effect (NAS, 1989). These markers are already used to detect a variety of diseases and show great promise for developing a better understanding of the mechanicisms of disease. Additionally, biomarkers can be used to establish a more rational basis for quantitative risk extrapolation between species, as weIl as to obtain more precise estimates of the time of critical exposure. These markers can also prove helpful in identifying potentially damaging exposures before the onset of adverse health effects. Biomarkers serve as a valuable exposure assessment tool because they take into account exposure from all routes and integrate exposure from all sources. They have the potential to yield better risk estimates than current monitoring and modeling protocols. In lune 1992, Dr. Travis and Dr.
Bioindicators and Biomarkers of Environmental Pollution and Risk Assessment
Author: Jamil KaiserPublisher:
ISBN:
Category : Nature
Languages : en
Pages : 230
Book Description
Provides the reader with an overview of the variety of animal and plants that are available for use as environmental monitors. The author emphasizes that the use of a single species of target bioindicator is not appropriate or scientifically sound for the monitoring of several toxic pollutants.
The Role and Potential Use of Biomarkers in Environmental Exposure Assessments
Author: Timothy ChandlerUse of Biomarkers for Environmental Quality Assessment
Author: Jean-Claude AmiardPublisher: CRC Press
ISBN: 1000448371
Category : Technology & Engineering
Languages : en
Pages : 370
Book Description
This work is primarily designed for any person or organization in charge of assessment of the quality of natural resources and of pollution prevention.
Biomarkers of Exposure, Effect and Susceptibility to Environmental and Occupational Chemicals
Author: Manosij GhoshPublisher: Frontiers Media SA
ISBN: 2889718344
Category : Science
Languages : en
Pages : 221
Book Description
Biological Monitoring
Author: M. E. ContiPublisher: WIT Press
ISBN: 1845640020
Category : Technology & Engineering
Languages : en
Pages : 257
Book Description
The aim of this book is to provide the reader with a basic understanding of the use of bioindicators both in assessing environmental quality and as a means of support in environmental impact assessment (EIA) procedures.
Biomarkers
Author: David B. PeakallPublisher: Springer
ISBN:
Category : Science
Languages : en
Pages : 152
Book Description
Biological markers used to assess the effects of environmental pollution have attracted considerable attention from regulatory agencies and are currently under evaluation at a number of research facilities throughout the world. However promising a biomarker-based biomonitoring approach may be, the development of this concept is complicated by a range of technical issues. This book provides a conceptional framework for research and application of biomarkers. International experts on biomonitoring have formulated a unified strategy for the development and validation of biomarkers in assessing environmental health as well as appropriate protocols for their implementation and interpretation in a biological monitoring program.
Human Biomonitoring for Environmental Chemicals
Author: National Research CouncilPublisher: National Academies Press
ISBN: 0309133904
Category : Science
Languages : en
Pages : 316
Book Description
Biomonitoring—a method for measuring amounts of toxic chemicals in human tissues—is a valuable tool for studying potentially harmful environmental chemicals. Biomonitoring data have been used to confirm exposures to chemicals and validate public health policies. For example, population biomonitoring data showing high blood lead concentrations resulted in the U.S. Environmental Protection Agency's (EPA's) regulatory reduction of lead in gasoline; biomonitoring data confirmed a resultant drop in blood lead concentrations. Despite recent advances, the science needed to understand the implications of the biomonitoring data for human health is still in its nascent stages. Use of the data also raises communication and ethical challenges. In response to a congressional request, EPA asked the National Research Council to address those challenges in an independent study. Human Biomonitoring for Environmental Chemicals provides a framework for improving the use of biomonitoring data including developing and using biomarkers (measures of exposure), research to improve the interpretation of data, ways to communicate findings to the public, and a review of ethical issues.