Author: Jaemoon Yang
Publisher: Elsevier
ISBN: 0128110414
Category : Science
Languages : en
Pages : 132
Book Description
Deuterium: Discovery and Applications in Organic Chemistry provides a well-illustrated overview of the discovery of 2H or heavy hydrogen, the stable hydrogen isotope with both a proton and a neutron in its nucleus. The work introduces the isotope, its discovery, physical properties, nomenclature, and common compounds, also exploring its application in organic chemistry through classic and recent examples from literature. Finally, the book devotes one chapter to Deuterium in medicinal chemistry and the biological effects of Deuterium Oxide, better known as D2O. - Provides unique coverage not found elsewhere that is presented in an accessible, dedicated short work - Contains practical information and examples on the use of Deuterium (D or 2H, Heavy Hydrogen) in organic synthesis - Presents a detailed description of Deuterium's discovery and applications in the pharmaceutical industry
Deuterium
Author: Jaemoon Yang
Publisher: Elsevier
ISBN: 0128110414
Category : Science
Languages : en
Pages : 132
Book Description
Deuterium: Discovery and Applications in Organic Chemistry provides a well-illustrated overview of the discovery of 2H or heavy hydrogen, the stable hydrogen isotope with both a proton and a neutron in its nucleus. The work introduces the isotope, its discovery, physical properties, nomenclature, and common compounds, also exploring its application in organic chemistry through classic and recent examples from literature. Finally, the book devotes one chapter to Deuterium in medicinal chemistry and the biological effects of Deuterium Oxide, better known as D2O. - Provides unique coverage not found elsewhere that is presented in an accessible, dedicated short work - Contains practical information and examples on the use of Deuterium (D or 2H, Heavy Hydrogen) in organic synthesis - Presents a detailed description of Deuterium's discovery and applications in the pharmaceutical industry
Publisher: Elsevier
ISBN: 0128110414
Category : Science
Languages : en
Pages : 132
Book Description
Deuterium: Discovery and Applications in Organic Chemistry provides a well-illustrated overview of the discovery of 2H or heavy hydrogen, the stable hydrogen isotope with both a proton and a neutron in its nucleus. The work introduces the isotope, its discovery, physical properties, nomenclature, and common compounds, also exploring its application in organic chemistry through classic and recent examples from literature. Finally, the book devotes one chapter to Deuterium in medicinal chemistry and the biological effects of Deuterium Oxide, better known as D2O. - Provides unique coverage not found elsewhere that is presented in an accessible, dedicated short work - Contains practical information and examples on the use of Deuterium (D or 2H, Heavy Hydrogen) in organic synthesis - Presents a detailed description of Deuterium's discovery and applications in the pharmaceutical industry
Spin Resonance Spectroscopy
Author: Chandran Karunakaran
Publisher: Elsevier
ISBN: 012813609X
Category : Science
Languages : en
Pages : 380
Book Description
Spin Resonance Spectroscopy: Principles and Applications presents the principles, recent advancements and applications of nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) in a single multi-disciplinary reference. Spin resonance spectroscopic techniques through NMR and EPR are widely used by chemists, physicists, biologists and medicinal chemists. This book addresses the need for new spin resonance spectroscopy content while also presenting the principles, recent advancements and applications of NMR and EPR simultaneously. Ideal for researchers and students alike, the book provides a single source of NMR and EPR applications using a dynamic, holistic and multi-disciplinary approach. - Presents a highly interdisciplinary approach by including NMR and EPR applications in chemistry, physics, biology and biotechnology - Addresses both NMR and EPR, making its concepts and applications implementable in multiple resonance environments and core scientific disciplines - Features a broad range of methods, examples and illustrations for both NMR and EPR to aid in retention and underscore key concepts
Publisher: Elsevier
ISBN: 012813609X
Category : Science
Languages : en
Pages : 380
Book Description
Spin Resonance Spectroscopy: Principles and Applications presents the principles, recent advancements and applications of nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) in a single multi-disciplinary reference. Spin resonance spectroscopic techniques through NMR and EPR are widely used by chemists, physicists, biologists and medicinal chemists. This book addresses the need for new spin resonance spectroscopy content while also presenting the principles, recent advancements and applications of NMR and EPR simultaneously. Ideal for researchers and students alike, the book provides a single source of NMR and EPR applications using a dynamic, holistic and multi-disciplinary approach. - Presents a highly interdisciplinary approach by including NMR and EPR applications in chemistry, physics, biology and biotechnology - Addresses both NMR and EPR, making its concepts and applications implementable in multiple resonance environments and core scientific disciplines - Features a broad range of methods, examples and illustrations for both NMR and EPR to aid in retention and underscore key concepts
Thermodynamic Properties of Cryogenic Fluids
Author: Richard T. Jacobsen
Publisher: Springer Science & Business Media
ISBN: 1489917985
Category : Technology & Engineering
Languages : en
Pages : 323
Book Description
Practicing engineers and scientist will benefit from this book's presentation of the most accurate information on the subject. The equations for fifteen important cryogenic fluids are presented in a basic format, accompanied by pressure-enthalpy and temperature-entropy charts and tables of thermodynamic properties. The book is supported by ICMPROPRS - an interactive computer program for the calculation of thermodynamic properties of the cryogenic fluids - that can be downloaded from the World Wide Web.
Publisher: Springer Science & Business Media
ISBN: 1489917985
Category : Technology & Engineering
Languages : en
Pages : 323
Book Description
Practicing engineers and scientist will benefit from this book's presentation of the most accurate information on the subject. The equations for fifteen important cryogenic fluids are presented in a basic format, accompanied by pressure-enthalpy and temperature-entropy charts and tables of thermodynamic properties. The book is supported by ICMPROPRS - an interactive computer program for the calculation of thermodynamic properties of the cryogenic fluids - that can be downloaded from the World Wide Web.
Comets II
Author: M. Festou
Publisher: University of Arizona Press
ISBN: 0816524505
Category : Science
Languages : en
Pages : 780
Book Description
The study of comets is a field that has seen tremendous advances in recent years, far surpassing the knowledge reflected in the original Comets volume published as part of the Space Science Series in 1982. This new volume, with more than seventy contributing authors, represents the first complete overview of comet science in more than a decade and contains the most extensive collection of knowledge yet assembled in the field. Comets II situates comet science in the global context of astrophysics for the first time by beginning with a series of chapters that describe the connection between stars and planets. It continues with a presentation of the formation and evolution of planetary systems, enabling the reader to clearly see the key role played in our own solar system by the icy planetesimals that were the seeds of the giant planets and transneptunian objects. The book presents the key results obtained during the 1990s, in particular those collected during the apparition of the exceptional comets C/Hyakutake and C/Hale-Bopp in 1996-1997. The latest results obtained from the in situ exploration of comets P/Borrelly and P/Wild 2 are also discussed in detail. Each topic of is designed to be accessible to students or young researchers looking for basic, yet detailed, complete and accurate, information on comet science. With its emphasis on the origin of theories and the future of research, Comets II will enable scientists to make connections across disciplinary boundaries and will set the stage for discovery and new understanding in the coming years.
Publisher: University of Arizona Press
ISBN: 0816524505
Category : Science
Languages : en
Pages : 780
Book Description
The study of comets is a field that has seen tremendous advances in recent years, far surpassing the knowledge reflected in the original Comets volume published as part of the Space Science Series in 1982. This new volume, with more than seventy contributing authors, represents the first complete overview of comet science in more than a decade and contains the most extensive collection of knowledge yet assembled in the field. Comets II situates comet science in the global context of astrophysics for the first time by beginning with a series of chapters that describe the connection between stars and planets. It continues with a presentation of the formation and evolution of planetary systems, enabling the reader to clearly see the key role played in our own solar system by the icy planetesimals that were the seeds of the giant planets and transneptunian objects. The book presents the key results obtained during the 1990s, in particular those collected during the apparition of the exceptional comets C/Hyakutake and C/Hale-Bopp in 1996-1997. The latest results obtained from the in situ exploration of comets P/Borrelly and P/Wild 2 are also discussed in detail. Each topic of is designed to be accessible to students or young researchers looking for basic, yet detailed, complete and accurate, information on comet science. With its emphasis on the origin of theories and the future of research, Comets II will enable scientists to make connections across disciplinary boundaries and will set the stage for discovery and new understanding in the coming years.
Biophysical Characterization of Proteins in Developing Biopharmaceuticals
Author: Damian J. Houde
Publisher: Elsevier
ISBN: 0444641742
Category : Medical
Languages : en
Pages : 588
Book Description
Biophysical Characterization of Proteins in Developing Biopharmaceuticals, Second Edition, presents the latest on the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure, this book explains the best way to achieve this goal using key methods commonly employed in the biopharmaceutical industry. This book will help today's industrial scientists plan a career in this industry and successfully implement these biophysical methodologies. This updated edition has been fully revised, with new chapters focusing on the use of chromatography and electrophoresis and the biophysical characterization of very large biopharmaceuticals. In addition, best practices of applying statistical analysis to biophysical characterization data is included, along with practical issues associated with the concept of a biopharmaceutical's developability and the technical decision-making process needed when dealing with biophysical characterization data. - Presents basic protein characterization methods and tools applicable to (bio)pharmaceutical research and development - Highlights the capabilities and limitations of each technique - Discusses the underlining science of each tool - Empowers industrial biophysical chemists by providing a roadmap for applying biophysical tools - Outlines the needs for new characterization and analytical tools in the biopharmaceutical industry
Publisher: Elsevier
ISBN: 0444641742
Category : Medical
Languages : en
Pages : 588
Book Description
Biophysical Characterization of Proteins in Developing Biopharmaceuticals, Second Edition, presents the latest on the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure, this book explains the best way to achieve this goal using key methods commonly employed in the biopharmaceutical industry. This book will help today's industrial scientists plan a career in this industry and successfully implement these biophysical methodologies. This updated edition has been fully revised, with new chapters focusing on the use of chromatography and electrophoresis and the biophysical characterization of very large biopharmaceuticals. In addition, best practices of applying statistical analysis to biophysical characterization data is included, along with practical issues associated with the concept of a biopharmaceutical's developability and the technical decision-making process needed when dealing with biophysical characterization data. - Presents basic protein characterization methods and tools applicable to (bio)pharmaceutical research and development - Highlights the capabilities and limitations of each technique - Discusses the underlining science of each tool - Empowers industrial biophysical chemists by providing a roadmap for applying biophysical tools - Outlines the needs for new characterization and analytical tools in the biopharmaceutical industry
Chemistry
Author: Bruce Averill
Publisher:
ISBN: 9780321413703
Category : Chemistry
Languages : en
Pages : 1233
Book Description
Emphasises on contemporary applications and an intuitive problem-solving approach that helps students discover the exciting potential of chemical science. This book incorporates fresh applications from the three major areas of modern research: materials, environmental chemistry, and biological science.
Publisher:
ISBN: 9780321413703
Category : Chemistry
Languages : en
Pages : 1233
Book Description
Emphasises on contemporary applications and an intuitive problem-solving approach that helps students discover the exciting potential of chemical science. This book incorporates fresh applications from the three major areas of modern research: materials, environmental chemistry, and biological science.
Encyclopedia of Geochemistry
Author: C.P. Marshall
Publisher: Springer Science & Business Media
ISBN: 0412755009
Category : Science
Languages : en
Pages : 677
Book Description
This is a complete and authoritative reference text on an evolving field. Over 200 international scientists have written over 340 separate topics on different aspects of geochemistry including organics, trace elements, isotopes, high and low temperature geochemistry, and ore deposits, to name just a few.
Publisher: Springer Science & Business Media
ISBN: 0412755009
Category : Science
Languages : en
Pages : 677
Book Description
This is a complete and authoritative reference text on an evolving field. Over 200 international scientists have written over 340 separate topics on different aspects of geochemistry including organics, trace elements, isotopes, high and low temperature geochemistry, and ore deposits, to name just a few.
Applied Biophysics for Drug Discovery
Author: Donald Huddler
Publisher: John Wiley & Sons
ISBN: 111909948X
Category : Science
Languages : en
Pages : 148
Book Description
Applied Biophysics for Drug Discovery is a guide to new techniques and approaches to identifying and characterizing small molecules in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment-based drug discovery and an increased focus on more nuanced characterisation of small molecule binding, these methods are playing an increasing role in discovery campaigns. This text emphasizes practical considerations for selecting and deploying core biophysical method, including but not limited to ITC, SPR, and both ligand-detected and protein-detected NMR. Topics covered include: • Design considerations in biophysical-based lead screening • Thermodynamic characterization of protein-compound interactions • Characterizing targets and screening reagents with HDX-MS • Microscale thermophoresis methods (MST) • Screening with Weak Affinity Chromatography • Methods to assess compound residence time • 1D-NMR methods for hit identification • Protein-based NMR methods for SAR development • Industry case studies integrating multiple biophysical methods This text is ideal for academic investigators and industry scientists planning hit characterization campaigns or designing and optimizing screening strategies.
Publisher: John Wiley & Sons
ISBN: 111909948X
Category : Science
Languages : en
Pages : 148
Book Description
Applied Biophysics for Drug Discovery is a guide to new techniques and approaches to identifying and characterizing small molecules in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment-based drug discovery and an increased focus on more nuanced characterisation of small molecule binding, these methods are playing an increasing role in discovery campaigns. This text emphasizes practical considerations for selecting and deploying core biophysical method, including but not limited to ITC, SPR, and both ligand-detected and protein-detected NMR. Topics covered include: • Design considerations in biophysical-based lead screening • Thermodynamic characterization of protein-compound interactions • Characterizing targets and screening reagents with HDX-MS • Microscale thermophoresis methods (MST) • Screening with Weak Affinity Chromatography • Methods to assess compound residence time • 1D-NMR methods for hit identification • Protein-based NMR methods for SAR development • Industry case studies integrating multiple biophysical methods This text is ideal for academic investigators and industry scientists planning hit characterization campaigns or designing and optimizing screening strategies.
Adsorption, Ion Exchange and Catalysis
Author: Stavros G. Poulopoulos
Publisher: Elsevier
ISBN: 0080463665
Category : Technology & Engineering
Languages : en
Pages : 615
Book Description
Adsorption, Ion Exchange and Catalysis is essentially a mixture of environmental science and chemical reactor engineering. More specifically, three important heterogeneous processes, namely, adsorption, ion exchange and catalysis, are analysed, from fundamental kinetics to reactor design with emphasis on their environmental applications. In Chapter 1, the subject of air and water pollution is dealt with. Data about pollutants and emission sources are given and the treatment methods are shortly presented. In Chapter 2, the very basics and historical development of adsorption, ion exchange and catalysis are presented as well as their environmental applications. Chapter 3 is devoted to heterogeneous processes and reactor analysis. All types of reactors are described in depth and reactor modelling, hydraulics and mass/heat transfer phenomena are examined for each type of reactor. Chapters 4 and 5 are dedicated to adsorption & ion exchange and catalysis, respectively. The basic principles are presented including kinetics, equilibrium, mass/heat transfer phenomena as well as the analytical solutions of the reactor models presented in Chapter 3. In the sixth chapter, the subject of scale up is approached. The two Annexes at the end of the book contain physical properties of substances of environmental interest as well as unit conversion tables. Finally, nearly all the examples contained are based on real experimental data found in literature with environmental interest. Most of the examples consider all aspects of operation design – kinetics, hydraulics and mass transfer.* Provides basic knowledge of major environmental problems and connects them to chemical engineering
Publisher: Elsevier
ISBN: 0080463665
Category : Technology & Engineering
Languages : en
Pages : 615
Book Description
Adsorption, Ion Exchange and Catalysis is essentially a mixture of environmental science and chemical reactor engineering. More specifically, three important heterogeneous processes, namely, adsorption, ion exchange and catalysis, are analysed, from fundamental kinetics to reactor design with emphasis on their environmental applications. In Chapter 1, the subject of air and water pollution is dealt with. Data about pollutants and emission sources are given and the treatment methods are shortly presented. In Chapter 2, the very basics and historical development of adsorption, ion exchange and catalysis are presented as well as their environmental applications. Chapter 3 is devoted to heterogeneous processes and reactor analysis. All types of reactors are described in depth and reactor modelling, hydraulics and mass/heat transfer phenomena are examined for each type of reactor. Chapters 4 and 5 are dedicated to adsorption & ion exchange and catalysis, respectively. The basic principles are presented including kinetics, equilibrium, mass/heat transfer phenomena as well as the analytical solutions of the reactor models presented in Chapter 3. In the sixth chapter, the subject of scale up is approached. The two Annexes at the end of the book contain physical properties of substances of environmental interest as well as unit conversion tables. Finally, nearly all the examples contained are based on real experimental data found in literature with environmental interest. Most of the examples consider all aspects of operation design – kinetics, hydraulics and mass transfer.* Provides basic knowledge of major environmental problems and connects them to chemical engineering
Tritium: Fuel of Fusion Reactors
Author: Tetsuo Tanabe
Publisher: Springer
ISBN: 4431564608
Category : Technology & Engineering
Languages : en
Pages : 365
Book Description
This book focuses on tritium as a fuel for fusion reactors and a next-generation energy source. Following an introduction of tritium as a hydrogen radioisotope, important issues involved in establishing safe and economical tritium fuel cycles including breeding for a fusion reactor are summarized; these include the handling of large amounts of tritium: confinement, leakage, contamination, permeation, regulation and tritium accountancy, and impacts on surrounding areas. Targeting and encouraging the students and technicians who will design and operate fusion reactors in the near future, this book offers a valuable resource on tritium science and technology.
Publisher: Springer
ISBN: 4431564608
Category : Technology & Engineering
Languages : en
Pages : 365
Book Description
This book focuses on tritium as a fuel for fusion reactors and a next-generation energy source. Following an introduction of tritium as a hydrogen radioisotope, important issues involved in establishing safe and economical tritium fuel cycles including breeding for a fusion reactor are summarized; these include the handling of large amounts of tritium: confinement, leakage, contamination, permeation, regulation and tritium accountancy, and impacts on surrounding areas. Targeting and encouraging the students and technicians who will design and operate fusion reactors in the near future, this book offers a valuable resource on tritium science and technology.