Human Herpesviruses: Diagnosis and Clinical Management PDF Download

Author: Aydan Jones
Publisher: Hayle Medical
ISBN: 9781646475391
Category : Medical
Languages : en
Pages : 0

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Book Description
Herpesvirus refers to a type of virus that belongs to the herpesviridae family. It has been classified into eight different types which include herpes simplex type I (HSV-1), herpes simplex type II (HSV-2), varicella-zoster virus (VZV/HHV-3), Epstein-Barr virus (EBV/HHV-4), cytomegalovirus (CMV/HHV-5), herpesvirus type 6 (HBLV/HHV-6), herpesvirus type 7 (HHV-7) and Kaposi's sarcoma herpesvirus (KSHV/HHV-8). Both direct and serologic techniques are used to diagnose the human herpesvirus 6 (HHV-6) infection. One of the most prominent techniques used for quantifying viral DNA in blood, organs and other body fluids is real-time PCR. There is currently no officially approved treatment for herpes infections. However, supportive therapy including sufficient hydration and acetaminophen for fever is recommended in all patients with symptomatic HHV-6 infection. This book is compiled in such a manner, that it will provide in-depth knowledge about the diagnosis and management of human herpesviruses. It will help new researchers by foregrounding their knowledge about this virus. The book will provide comprehensive knowledge to medical students and professionals.

Author: Louis Flamand
Publisher: Elsevier
ISBN: 0444627162
Category : Science
Languages : en
Pages : 362

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Book Description
Completely revised and updated, Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition, delivers a contemporary and thorough review of HHV-6, beginning with foundational explorations of classification, molecular biology, and chromosomal integration of the virus, through to clinical details, including pathologic features of infection, and clinical effects on various organ systems. The work now includes coverage of HHV-7, a virus that remains underestimated in transplant reactivation, seizures, and encephalitis. The book examines the role of HHV-6 in myriad diseases, including cognitive disorders following bone marrow transplant, mesial temporal lobe epilepsy, multiple sclerosis, autoimmune disease, encephalitis, Hodgkin's disease lymphoma (HHV-6B), and glioma (HHV-6A). Descriptions of current and novel molecular and serological diagnostic assays, along with detailed protocols, are included to aid researchers and clinicians in discriminating potential false positives originating from chromosomally integrated HHV-6, and in differentiating between active and latent infection. Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition is a valuable reference for both clinical and basic scientists, including epidemiologists, virologists, practicing clinicians, infectious disease specialists, pathologists, and all scientists entering the field of herpes virus research. The work is a practical and thorough resource for a foundational understanding of HHV-6 and HHV-7, while providing a cutting-edge translational and clinical reference to those looking to understand and diagnose associated viral diseases. Delivers the latest molecular diagnostic tests, the present-day gold standard for monitoring HHV-6 Provides expert analysis of T-cell immune response against HHV-6 Presents tools for differential diagnosis in HHV-6 viral infections Includes new information on the previously-largely-unknown biological consequences of ciHHV-6 Offers coverage of new discoveries relating to HHV-7

Author: Ann Arvin
Publisher: Cambridge University Press
ISBN: 1139461648
Category : Medical
Languages : en
Pages : 1325

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Book Description
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Author: Ronaldo Luis Thomasini
Publisher: BoD – Books on Demand
ISBN: 1838811583
Category : Medical
Languages : en
Pages : 130

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Book Description
The relationship between herpesviruses and humans probably dates from thousands of years ago. In the last few decades, many aspects of herpesvirus infections have been understood, such as infections with a range of manifestations (severe, mild, or subclinical). Herpesvirus can remain latent during a lifetime and sometimes their reactivation can cause different clinical features in the patient. Several conditions have been related to herpesvirus reactivation such as complications in transplant organ recipients and immune regulatory modification in the elderly. Aspects of human herpesvirus simples, varicella-zoster virus, and cytomegalovirus are presented and discussed in this book.

Author:
Publisher: Elsevier
ISBN: 008046128X
Category : Medical
Languages : en
Pages : 393

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Book Description
The present book presents a comprehensive review of Human Herpesvirus-6 (HHV-6) infects up to 90% of the world’s population and can cause potentially life-threatening diseases. Clinicians typically do not search for HHV-6, and if they do, they will find only few laboratories providing the necessary diagnostic tests that can differentiate between active and latent infection. Adding to this problem is that scientists still disagree about whether serological or molecular assays will be the best diagnostic test, yet there is no disagreement about the inadequacy of many of the currently existing assays. Consequently, our knowledge of etiology and pathogenesis of HHV-6 associated diseases can only come from the combined efforts of clinicians, virologists, molecular biologists and pathologists. It is the prime task of this book to summarize the status quo of HHV-6 research and to further stimulate such a collaboration. It will be a valuable reference for both clinical and basic scientists including epidemiologists, virologists, practicing clinicians and infectiologists, pathologists and essentially all scientists entering the field of herpes virus research.

Author: Stephen L. Sacks
Publisher: IOS Press
ISBN: 9789051992274
Category : Antiviral agents
Languages : en
Pages : 402

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Book Description
Much has been said about managing herpesvirus infections since the discovery of acyclovir more than 15 years ago. This book aims to bring practical advice to the key clinician who is faced with managing these infections. It addresses questions like: there are antiviral treatments for many of these infections, but who should be getting these drugs and who should not? What are the advantages, if any, of the new drugs over the old ones? Which patients should be targeted for intervention? What is the clinical reality of antiviral resistance? Where do the up and coming vaccines fit into the picture? When should therapy be discontinued or reassessed? How are patients presenting other than chorioretinitis in AIDS or pneumonitis in transplantation? The contributing clinician scientists deal with these questions and many more. Listed by Biological Abstracts/RRM, BIOSIS, volume 48, issue 8, August 1995 Covered by Current Contents, Life Sciences (ISI), volume 39, no. 2, Januari 1996, p. 12

Author: Bernard Roizman
Publisher: Raven Press (ID)
ISBN:
Category : Medical
Languages : en
Pages : 458

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Book Description

Author: Yasushi Kawaguchi
Publisher: Springer
ISBN: 9811072302
Category : Medical
Languages : en
Pages : 498

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Book Description
This book introduces and reviews several topics for each human herpesvirus. One of the most important features of the book is that it covers aspects of both basic research and clinical medicine. Herpesviridae, a family of double-strand DNA viruses, has unique biological features by which these viruses establish latency after primary infection and reactivate in later life. Nine human herpesviruses are known so far, and each of them causes a variety of diseases in both primary infection and reactivation. Since the discovery of each human herpesvirus, an abundance of findings related to them has accumulated in basic research and clinical medicine. However, the vast majority of biological features is still masked in mystery. Furthermore, a strategy of treatment and prevention has not yet been established for most human herpesviruses. A wide range of readers will be interested in this volume with its treatment of problematic points and latest findings in the field.

Author: Carlos Lopez
Publisher:
ISBN: 9780608034287
Category :
Languages : en
Pages : 318

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Book Description

Author: Crispian Scully
Publisher: Academic Press
ISBN: 0128136820
Category : Medical
Languages : en
Pages : 124

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Book Description
Saliva Protection and Transmissible Diseases provides a review of saliva protection, raising debate on micro-organisms potentially transmissible in saliva, and also considering the evidence on diseases that may be transmitted by kissing. Saliva is a complex body fluid essential to health, especially mastication, swallowing and speech, and hyposalivation can lead to dysfunction and even infection. More serious pathogens, such as herpes viruses and papillomaviruses can be conveyed by kissing, as can potentially lethal micro-organisms present in some saliva, such as meningococci, fungal organisms and Ebola viruses. Stipulates the defensive roles of saliva, an important topic not previously reviewed in-depth in literature Provides awareness that saliva also transmits infectious agents that can produce serious or even lethal diseases Gives understanding that kissing may be an at-risk practice