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Human Microbiome

Human Microbiome PDF Author: Sabu Thomas
Publisher: Springer
ISBN: 9789811676741
Category : Medical
Languages : en
Pages : 0

Book Description
The human microbiome refers to the complete microorganisms inhabiting the human body sites including skin, ear, nose, oral cavity, the genital, gastrointestinal and respiratory tracts, and body fluids such as breast milk, saliva, and urine. It is a significant and essential organ recognized for the body and has an established involvement in the host wellbeing, in terms of nutritional requirements and immunomodulation. This book talks about how alteration and imbalance in the same can have clinical implications associated with a multitude of gastrointestinal, lifestyle-associated, and neurodegenerative disorders. How the proliferation of specific groups of bacteria and their metabolic activities, as a result of intestinal dysbiosis leads to the 'leaky gut' condition thereby influences brain activity via the bidirectional gut-brain axis. It also coves the importance of microbial seeding and how it can be influenced by the mode of delivery, nutrition, and medication. This book also provides various therapeutic interventions such as the establishment of stool banks and Faecal microbiota transplantation (FMT) that have recently proved promising in the treatment of ASD, Inflammatory Bowel Disease, and Ulcerative Colitis. This book provides a deeper understanding of the development of the human gut microbiome and the factors driving its dysbiosis. This book is a valuable read for health professionals, medical students, nutritionists, and scientific research communities who are eager to update themselves with recent trends in microbiome research. It will also aid gastroenterologists and nutritionists to make well-informed choices regarding therapeutic regimes.

Human Microbiome

Human Microbiome PDF Author: Sabu Thomas
Publisher: Springer
ISBN: 9789811676741
Category : Medical
Languages : en
Pages : 0

Book Description
The human microbiome refers to the complete microorganisms inhabiting the human body sites including skin, ear, nose, oral cavity, the genital, gastrointestinal and respiratory tracts, and body fluids such as breast milk, saliva, and urine. It is a significant and essential organ recognized for the body and has an established involvement in the host wellbeing, in terms of nutritional requirements and immunomodulation. This book talks about how alteration and imbalance in the same can have clinical implications associated with a multitude of gastrointestinal, lifestyle-associated, and neurodegenerative disorders. How the proliferation of specific groups of bacteria and their metabolic activities, as a result of intestinal dysbiosis leads to the 'leaky gut' condition thereby influences brain activity via the bidirectional gut-brain axis. It also coves the importance of microbial seeding and how it can be influenced by the mode of delivery, nutrition, and medication. This book also provides various therapeutic interventions such as the establishment of stool banks and Faecal microbiota transplantation (FMT) that have recently proved promising in the treatment of ASD, Inflammatory Bowel Disease, and Ulcerative Colitis. This book provides a deeper understanding of the development of the human gut microbiome and the factors driving its dysbiosis. This book is a valuable read for health professionals, medical students, nutritionists, and scientific research communities who are eager to update themselves with recent trends in microbiome research. It will also aid gastroenterologists and nutritionists to make well-informed choices regarding therapeutic regimes.

The Chemistry of Microbiomes

The Chemistry of Microbiomes PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309458390
Category : Science
Languages : en
Pages : 133

Book Description
The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.

Environmental Chemicals, the Human Microbiome, and Health Risk

Environmental Chemicals, the Human Microbiome, and Health Risk PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309468698
Category : Science
Languages : en
Pages : 123

Book Description
A great number of diverse microorganisms inhabit the human body and are collectively referred to as the human microbiome. Until recently, the role of the human microbiome in maintaining human health was not fully appreciated. Today, however, research is beginning to elucidate associations between perturbations in the human microbiome and human disease and the factors that might be responsible for the perturbations. Studies have indicated that the human microbiome could be affected by environmental chemicals or could modulate exposure to environmental chemicals. Environmental Chemicals, the Human Microbiome, and Health Risk presents a research strategy to improve our understanding of the interactions between environmental chemicals and the human microbiome and the implications of those interactions for human health risk. This report identifies barriers to such research and opportunities for collaboration, highlights key aspects of the human microbiome and its relation to health, describes potential interactions between environmental chemicals and the human microbiome, reviews the risk-assessment framework and reasons for incorporating chemicalâ€"microbiome interactions.

The Human Microbiome, Diet, and Health

The Human Microbiome, Diet, and Health PDF Author: Food Forum
Publisher: National Academies Press
ISBN: 030926586X
Category : Medical
Languages : en
Pages : 197

Book Description
The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.

Comprehensive Gut Microbiota

Comprehensive Gut Microbiota PDF Author:
Publisher: Elsevier
ISBN: 9780128192658
Category : Science
Languages : en
Pages :

Book Description
Comprehensive Gut Microbiota provides new insights into gut microbiota as a critical mediator of human health and well-being. Comprehensive chapters, split across three volumes, present trusted and authoritative sources of information for novel human gut microbiome and health research. The book focuses on the fascinating intestinal microbiome and its interaction with food, food bioactive components, nutrition and human health. Chapters address the core science in the microbiota field and draw links between the microbiome, food, nutrition and health interaction. The text reflects the current state of evidence available in the field of microbiota, its regulation at the individual and population level, and the importance of the microbiome to human health. Each section includes introductory chapters presenting the key concepts about the section objective. Later sections focus on the novel findings of the gut microbiome, food and nutrition science. Human studies and systematic literature reviews are also discussed throughout the work. Provides a comprehensive introduction to gut microbiota research and its role and relation to human health Consolidates new research on how gut microbiota affects nutrition and vice versa, offering increased understanding of methodologies and the complexity of microbiome-health science Written by leading experts from various fields and regions to ensure that the knowledge within is easily understood by, and applicable to, a large audience

The Gut Microbiome in Health and Disease

The Gut Microbiome in Health and Disease PDF Author: Dirk Haller
Publisher: Springer
ISBN: 3319905457
Category : Medical
Languages : en
Pages : 356

Book Description
The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

The Handbook of Metabolic Phenotyping

The Handbook of Metabolic Phenotyping PDF Author: John C. Lindon
Publisher: Elsevier
ISBN: 0128122943
Category : Science
Languages : en
Pages : 619

Book Description
The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts with many years of practice in the field who pioneered many of the approaches widely used today, The Handbook of Metabolic Phenotyping is a valuable resource for postgrads and research scientists studying and furthering the field of metabolomics. Contains theoretical and practical explanations of all the main analytical chemistry techniques used in metabolic phenotyping Explores, in detail, the many diverse statistical approaches used in the field Offers practical tips for successfully conducting metabolic phenotyping studies Features reviews of all of the various fields of activity relating to human studies

Work & The Health Of Women

Work & The Health Of Women PDF Author: Vilma Hunt
Publisher: CRC Press
ISBN: 1000083616
Category : Medical
Languages : en
Pages : 336

Book Description
First Published in 1979, this book offers an analytical summary of the relationship between women, their health, and the workplace. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for environmental health experts, and other practitioners in their respective fields.

Gut Microbiome-Related Diseases and Therapies

Gut Microbiome-Related Diseases and Therapies PDF Author: Maria Gazouli
Publisher: Springer Nature
ISBN: 3030596427
Category : Medical
Languages : en
Pages : 328

Book Description
This book reviews recent knowledge of the role of gut microbiome in health and disease. It covers extensive topics for several diseases, including metabolic-related diseases, allergies, gastrointestinal diseases, psychiatric diseases, and cancer, while also discussing therapeutic approaches by microbiota modification. Comprehensive and cutting-edge, Gut Microbiome-Related Diseases and Therapies deepens a reader’s theoretical expertise in gut microbiome. Graduate and postdoctoral students, medical doctors, and biomedical researchers will benefit from this book.

Gut Feelings

Gut Feelings PDF Author: Alessio Fasano
Publisher: MIT Press
ISBN: 0262044277
Category : Science
Languages : en
Pages : 551

Book Description
Why the microbiome--our rich inner ecosystem of microorganisms--may hold the keys to human health. We are at the dawn of a new scientific revolution. Our understanding of how to treat and prevent diseases has been transformed by knowledge of the microbiome--the rich ecosystem of microorganisms that is in and on every human. These microbial hitchhikers may hold the keys to human health. In Gut Feelings, Alessio Fasano and Susie Flaherty show why we must go beyond the older, myopic view of microorganisms as our enemies to a broader understanding of the microbiome as a parallel civilization that we need to understand, respect, and engage with for the benefit of our own health.