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Author: Papadoyannis Publisher: CRC Press ISBN: 9780824781392 Category : Science Languages : en Pages : 510
Book Description
Based on the use of high-performance liquid chromatography (HPLC) as a means to assess quantities of separated components in HPLC detectors, this volume is structured for use by analysts who have some experience in chemical analysis or have done HPLC. It keeps theory and instrumentation at a minimum
Author: Papadoyannis Publisher: CRC Press ISBN: 9780824781392 Category : Science Languages : en Pages : 510
Book Description
Based on the use of high-performance liquid chromatography (HPLC) as a means to assess quantities of separated components in HPLC detectors, this volume is structured for use by analysts who have some experience in chemical analysis or have done HPLC. It keeps theory and instrumentation at a minimum
Author: Roger Bertholf Publisher: John Wiley & Sons ISBN: 0470023104 Category : Science Languages : en Pages : 308
Book Description
This book aims to fill the gap that exists between theoretical treatments of chromatography, and clinical chemistry and toxicology texts, which focus almost exclusively on clinical relevance and applications. Chromatography has a vast array of clinical applications, and though the chromatographic methods were first introduced decades ago, new applications of this technology are being used to explore previously inaccessible frontiers in clinical diagnostics and toxicological testing. An up-to-date book devoted to clinical and toxicological applications of chromatographic methods will serve as an instructional and reference text, useful to students, laboratory technicians, and researchers.
Author: Joel K. Swadesh Publisher: CRC Press ISBN: 1420042661 Category : Science Languages : en Pages : 480
Book Description
Product specifications, regulatory constraints, and tight production schedules impose considerable pressures on separation scientists in industry. The first edition of HPLC: Practical and Industrial Applications helped eliminate the need for extensive library or laboratory research when confronting a problem, an unfamiliar technique, or work in a n
Author: Satinder Ahuja Publisher: Elsevier ISBN: 0080554199 Category : Medical Languages : en Pages : 532
Book Description
High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase
Author: Yuri V. Kazakevich Publisher: John Wiley & Sons ISBN: 0470087943 Category : Science Languages : en Pages : 1136
Book Description
HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.