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The Gene

The Gene PDF Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
ISBN: 1476733538
Category : Medical
Languages : en
Pages : 624

Book Description
The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

The Gene

The Gene PDF Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
ISBN: 1476733538
Category : Medical
Languages : en
Pages : 624

Book Description
The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

The Gene

The Gene PDF Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
ISBN: 1476733503
Category : History
Languages : en
Pages : 608

Book Description
Prologue: Families -- "The missing science of heredity" 1865-1935 -- "In the sum of the parts, there are only the parts" 1930-1970 -- "The dreams of geneticists" 1970-2001 -- "The proper study of mankind is man" 1970-2005 -- Through the looking glass 2001-2015 -- Post-genome 2015- ... -- Epilogue: Bheda, Abheda

A History of Genetics

A History of Genetics PDF Author: Alfred Henry Sturtevant
Publisher: CSHL Press
ISBN: 9780879696078
Category : Medical
Languages : en
Pages : 190

Book Description
In the small “Fly Room†at Columbia University, T.H. Morgan and his students, A.H. Sturtevant, C.B. Bridges, and H.J. Muller, carried out the work that laid the foundations of modern, chromosomal genetics. The excitement of those times, when the whole field of genetics was being created, is captured in this book, written in 1965 by one of those present at the beginning. His account is one of the few authoritative, analytic works on the early history of genetics. This attractive reprint is accompanied by a website, http://www.esp.org/books/sturt/history/ offering full-text versions of the key papers discussed in the book, including the world's first genetic map.

Summary and Analysis of The Gene: An Intimate History

Summary and Analysis of The Gene: An Intimate History PDF Author: Worth Books
Publisher: Open Road Media
ISBN: 1504043383
Category : Study Aids
Languages : en
Pages : 40

Book Description
So much to read, so little time? This brief overview of The Gene tells you what you need to know—before or after you read Siddhartha Mukherjee’s book. Crafted and edited with care, Worth Books set the standard for quality and give you the tools you need to be a well-informed reader. This short summary and analysis of The Gene by Siddhartha Mukherjee includes: Historical context Chapter-by-chapter summaries Detailed timeline of key events Important quotes Fascinating trivia Glossary of terms Supporting material to enhance your understanding of the original work About Siddhartha Mukherjee’s The Gene: From the Pulitzer Prize–winning author of The Emperor of All Maladies, The Gene is a rigorously scientific, broadly historical, and candidly personal account of the development of the science of genetics, the dramatic ways genes can affect us, and the enormous moral questions posed by our ability to manipulate them. As Siddhartha Mukherjee maps out the fascinating biography of the gene, from research and experimentation to scientific breakthroughs, he always returns to the narrative of his own family’s tragic history of mental illness, reminding us that despite our huge leaps in knowledge, there is still much we do not understand about the incredibly complex human genome. The Gene is an important read for anyone concerned about a future that may redefine what it means to be human. The summary and analysis in this ebook are intended to complement your reading experience and bring you closer to a great work of nonfiction.

The Laws of Medicine

The Laws of Medicine PDF Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
ISBN: 147678485X
Category : Medical
Languages : en
Pages : 96

Book Description
Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

Who is the Scientist-Subject?

Who is the Scientist-Subject? PDF Author: Esha Shah
Publisher: Taylor & Francis
ISBN: 0429953178
Category : Philosophy
Languages : en
Pages : 247

Book Description
This book explores two disparate sets of debates in the history and philosophy of the life sciences: the history of subjectivity in shaping objective science and the history of dominance of reductionism in molecular biology. It questions the dominant conception of the scientist-subject as a neo-Kantian ideal self – that is, the scientist as a unified and wilful, self-determined, self-regulated, active and autonomous, rational subject wilfully driven by social and scientific ethos – in favour of a narrative that shows how the microcosm of reductionism is sustained, adopted, questioned, or challenged in the creative struggles of the scientist-subject. The author covers a century-long history of the concept of the gene as a series of "pioneering moments" through an engagement with life-writings of eminent scientists to show how their ways of being and belonging relate with the making of the science. The scientist-self is theorized as fundamentally a feeling, experiencing, and suffering subject split between the conscious and unconscious and constitutive of personality aspects that are emotional/psychological, "situated" (cultural and ideological), metaphysical, intersubjective, and existential at the same time. An engaging interdisciplinary interpretation of the dominance of reductionism in genetic science, this book will be of major interest to scholars and researchers of science, history, and philosophy alike.

Gene Tierney

Gene Tierney PDF Author: Michelle Vogel
Publisher: McFarland
ISBN: 0786458321
Category : Performing Arts
Languages : en
Pages : 248

Book Description
Called the most beautiful woman in movie history, Gene Tierney starred in such 1940s classics as Laura, Leave Her to Heaven and The Ghost and Mrs. Muir. Her on-screen presence and ability to transform into a variety of characters made her a film legend. Her personal life was a whirlwind of romance (she married a count, was engaged to a prince, and was courted by a future president) and tragedy (her first daughter was born with severe retardation and Tierney herself struggled with mental illness). After years of treatment, including electroshock therapy that erased portions of her life from her memory, she triumphantly returned in one of the biggest comebacks in Hollywood history. This first complete biography since the actress's death includes a foreword by her daughter, Christina Cassini, an extensive filmography, and many rare photographs.

The Practical Guide to the Genetic Family History

The Practical Guide to the Genetic Family History PDF Author: Robin L. Bennett
Publisher: John Wiley & Sons
ISBN: 1118209818
Category : Medical
Languages : en
Pages : 389

Book Description
HELPS YOU DEVELOP AND ASSESS PEDIGREES TO MAKE DIAGNOSES, EVALUATE RISK, AND COUNSEL PATIENTS The Second Edition of The Practical Guide to the Genetic Family History not only shows how to take a medical-family history and record a pedigree, but also explains why each bit of information gathered is important. It provides essential support in diagnosing conditions with a genetic component. Moreover, it aids in recommending genetic testing, referring patients for genetic counseling, determining patterns of inheritance, calculating risk of disease, making decisions for medical management and surveillance, and informing and educating patients. Based on the author's twenty-five years as a genetic counselor, the book also helps readers deal with the psychological, social, cultural, and ethical problems that arise in gathering a medical-family history and sharing findings with patients. Featuring a new Foreword by Arno Motulsky, widely recognized as the founder of medical genetics, and completely updated to reflect the most recent findings in genetic medicine, this Second Edition presents the latest information and methods for preparing and assessing a pedigree, including: Value and utility of a thorough medical-family history Directed questions to ask when developing a medical-family history for specific disease conditions Use of pedigrees to identify individuals with an increased susceptibility to cancer Verification of family medical information Special considerations when adoptions or gamete donors are involved Ethical issues that may arise in recording a pedigree Throughout the book, clinical examples based on hypothetical families illustrate key concepts, helping readers understand how real issues present themselves and how they can be resolved. This book will enable all healthcare providers, including physicians, nurses, medical social workers, and physician assistants, as well as genetic counselors, to take full advantage of the pedigree as a primary tool for making a genetic risk assessment and providing counseling for patients and their families.

Gene Person Story

Gene Person Story PDF Author: Gene Person
Publisher: AuthorHouse
ISBN: 1434386406
Category : Biography & Autobiography
Languages : en
Pages : 142

Book Description
The Greek pre-Socratic philosophers Thales, Anaximander and Anaximenes of Miletus are generally considered the intellectual revolutionaries and founders of Western philosophy and science. They appear in the literature as "the first" in long lineages of individuals who have contributed to the advancement of ideas and knowledge. They are, however, not the only Milesians who have made their imprints on the pages of history and literature. The classical texts mention in excess of 200 historical and legendary citizens, and occasional residents, who prior to and following Thales made their marks in astronomy, geometry, mathematics, history, law, politics, cartography, town-planning, poetry, rhetoric, architecture and more. The story begins with the establishment of Minoan and Mycaenean settlements in southern Anatolia, and the legendary founders and citizens of Miletus. It moves on to a more detailed discussion of the lives and contributions of the natural philosophers Thales and his associates Anaximander and Anaximenes, and beyond them to an interesting variety of gifted citizens and residents, all of whom brought fame to the ancient city during the Ionian rebellion, the Persian and Peloponnesian wars, the conquest of Ionia by Alexander the Great, and the fragmentation of Alexander''s empire during the time of the Diadochii, or "War of the Generals". It concludes with the domination of Asia Minor by the Romans during the late Republic and Empire up to the end of the Byzantine period. It is an exciting ''Anthology'' of a city and its talented achievers as set against a background of widely different political circumstances, regional conflicts, rebellions, wars and occupations first under the Hittites, and then under the rulers of Persia, Greece, Sparta, Macedonia, Egypt, Syria, Rome, Byzantium and the Turks. The subject is of ongoing interest to historians, archaeologists and students of classical history, literature, science, religion and philosophy, as well as to amateurs and laymen who are keenly interested in Mediterranean antiquity. The purpose of the story is to stimulate interest, elicit dialogue, and provide readers with a fair measure of enjoyment.

A Brief History of Everyone who Ever Lived

A Brief History of Everyone who Ever Lived PDF Author: Adam Rutherford
Publisher: George Weidenfeld & Nicholson
ISBN: 9781780229072
Category : Medical
Languages : en
Pages : 0

Book Description
'A brilliant, authoritative, surprising, captivating introduction to human genetics. You'll be spellbound' Brian Cox This is a story about you. It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species - births, deaths, disease, war, famine, migration and a lot of sex. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about human history, and what history can now tell us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be. *** 'A thoroughly entertaining history of Homo sapiens and its DNA in a manner that displays popular science writing at its best' Observer 'Magisterial, informative and delightful' Peter Frankopan 'An extraordinary adventure...From the Neanderthals to the Vikings, from the Queen of Sheba to Richard III, Rutherford goes in search of our ancestors, tracing the genetic clues deep into the past' Alice Roberts