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Author: Irving Sucholeiki Publisher: CRC Press ISBN: 9781420056518 Category : Science Languages : en Pages : 398
Book Description
An exploration of high-throughput synthesis, this book presents a compilation of how-to methods, novel materials, and catalyst developments for creating a multitude of new compounds. Introductory sections are coupled with in-depth case studies clarifying theory through practice. The book emphasizes the potential for reproducing experiments in detail.
Author: Irving Sucholeiki Publisher: CRC Press ISBN: 9781420056518 Category : Science Languages : en Pages : 398
Book Description
An exploration of high-throughput synthesis, this book presents a compilation of how-to methods, novel materials, and catalyst developments for creating a multitude of new compounds. Introductory sections are coupled with in-depth case studies clarifying theory through practice. The book emphasizes the potential for reproducing experiments in detail.
Author: Tushar Kshirsagar Publisher: CRC Press ISBN: 1420006967 Category : Medical Languages : en Pages : 256
Book Description
A Single Source on Parallel Synthesis for Lead Optimization The end of the previous millennium saw an explosion in the application of parallel synthesis techniques for making compounds for high-throughput screening. Over time, it became clear that more thought in the design phase of library development is necessary to generate high qualit
Author: James Kyranos Publisher: Elsevier ISBN: 0080472923 Category : Science Languages : en Pages : 204
Book Description
High Throughput Analysis for Early Drug Discovery offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate types of analysis, each chapter or section begins with a description of the synthesis approach and its advantages. The description of various combinatorial and high-throughput parallel synthesis techniques provide a relevant point of entry for synthetic chemists who need to set up appropriate characterisation methods for his/her organisation. This is an invaluable resource for all organic and analytical chemists in the pharmaceutical, agrochemical, and biotechnology fields who are either involved in, or beginning to investigate combinatorial techniques to increase overall efficiency and productivity. First reference to focus on the analytical side of synthesis
Author: Alfred Hagemeyer Publisher: Wiley-VCH ISBN: Category : Science Languages : en Pages : 352
Book Description
This first comprehensive book on heterogeneous catalysis provides an up-to-date overview of the current status and advances being made in this rapidly growing field. The authors from both academia and industry apply HTS to the discovery and optimization of complex multi-component heterogeneous catalysts and electrocatalysts, while also analyzing its capabilities and limitations. They also include CombiCatalysis, screening and optimization strategies, as well as aspects of electrocatalysis, and make use of various industrial methodologies, such as those of Avantium, H.T.E., Symyx, Sintef and IMM, to demonstrate the various approaches to overcoming the challenges of miniaturization. The text is supported throughout by numerous tables, illustrations, graphs, and photographs of synthesis and reactor equipment, most of them in color. For advanced students, catalytic or solid-state chemists in R&D and engineers specializing in reactor technology, detection schemes and automation.
Author: Marion H. Emmert Publisher: ISBN: 9780841297562 Category : Biopharmaceutics Languages : en Pages : 0
Book Description
"High-throughput experimentation (HTE) is an emerging and powerful approach to problems in organic chemistry and homogeneous catalysis. This book is targeted at both experts and those new to the field who are seeking general perspectives and design principles for how to build and implement HTE capabilities. Specific examples of high-throughput experimental design and execution in the context of organic synthesis are included. Volume 1 covers general topics, including the history of HTE and its transition from highly specialized groups to more general adoption across industry and academia, along with the current state-of-the-art with respect to high-throughput technologies, including photo- and electrochemistry, nanoscale reactions, and others. Chapters are authored by practitioners in industry and academia, showcasing how a high-throughput mindset enables rapid optimization of existing chemistries and discovery of new reactivity."--
Author: Alfred Hagemeyer Publisher: John Wiley & Sons ISBN: 3527604308 Category : Science Languages : en Pages : 339
Book Description
In this first book to present every important aspect of this fascinating and developing field, the three editors A. Hagemeyer, P. Strasser and A. F. Volpe Jr. from Symyx Technologies have chosen a perfect mixture of distinguished, international authors from both academia and industry. Each chapter is devoted to a major topic - high-throughput experimentation methodologies, integrated combinatorial synthesis and screening workflow, and applications to chemical catalysts with an emphasis on heterogeneous catalysis, olefin polymerization and electrocatalysis for fuel cells. An indispensable source for everyone working in the field.
Author: Jörg Hüser Publisher: John Wiley & Sons ISBN: 3527609369 Category : Science Languages : en Pages : 362
Book Description
Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmaceutical companies as well as from Harvard University discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the efficient use of compound libraries and data mining using cell-based assay results. For both academics and professionals in the pharma and biotech industries working on small molecule screening.
Author: E.G. Derouane Publisher: Springer Science & Business Media ISBN: 9401143293 Category : Science Languages : en Pages : 497
Book Description
Catalysts are central in modern industrial chemistry and there is an urgent need to develop new catalysts. Such a rapid pace of development brings with it a new set of challenges at all levels of research, from synthesis and characterization to testing and modelling. This book reviews the current status of combinatorial catalysis, scientific catalyst design techniques, methods for preparing inorganic combinatorial libraries, experimental design methods, data processing, system modelling an simulation, and catalyst testing. The individual contributions reveal the development of high throughput catalyst design and test methods and identify the main challenges in the field, including new catalyst preparation techniques, rapid performance evaluation, and new microreactor configurations. Readership: All those working in catalytic process analysis and development. The extensive review of catalysis principles is especially relevant for postgraduate students seeking to pursue studies in catalysis.
Author: Irving Sucholeiki
Author: Irving Sucholeiki
Author: Tushar Kshirsagar
Author: James Kyranos
Author: Alfred Hagemeyer
Author: Marion H. Emmert
Author: Alfred Hagemeyer
Author: Jörg Hüser
Author: E.G. Derouane
Author: Eric Valeur
Author: Eric Valeur