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Hepatotoxicity

Hepatotoxicity PDF Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 848

Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Hepatotoxicity

Hepatotoxicity PDF Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 848

Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Drug Hepatotoxicity, An Issue of Clinics in Liver Disease, E-Book

Drug Hepatotoxicity, An Issue of Clinics in Liver Disease, E-Book PDF Author: Vinod Rustgi
Publisher: Elsevier Health Sciences
ISBN: 0323496628
Category : Medical
Languages : en
Pages : 276

Book Description
Dr. Rustgi has assembled the leading experts in the management of Heptatitis B to present the current treatment and clinical course for diagnosis and management of the disease. Articles are devoted to: Drug metabolism in the liver; Mechanism of Liver Damage including the RUCAM scale; Drug-induced acute liver failure; Epidemiology and genetic risk factors; Adverse drug reactions: type A (intrinsic or pharmacological) or type B (idiosyncratic); Pathology of injury including phenotypes; The clinical course of drug-induced liver disease; Environmental factors of drug hepatotoxicity; Newer agents in drug hepatotoxicity; Drug hepatotoxicity: herbal products; Drug hepatotoxicity: models including “human on a chip and zebrafish; Acute and chronic liver failure from drugs: impact on the kidney; and Management of acute hepatotoxicity including medical agents and liver support systems. Readers will come away with the cutting edge science behind the latest innovations in the treatment of Hepatitis B.

Drug Hepatotoxicity, An Issue of Clinics in Liver Disease

Drug Hepatotoxicity, An Issue of Clinics in Liver Disease PDF Author: Nicholaos Pyrsopoulos
Publisher: Elsevier Health Sciences
ISBN: 0323261078
Category : Medical
Languages : en
Pages : 298

Book Description
Dr. Pyrsopolous has created a comprehensive review on the most important and timely topics in drug heptatotoxicity. He has arraanged for there to be a full span of very basic articles that discuss drug metabolism, hepatotoxicity, and drug-induced acute liver failure as well as other important articles devoted to clinical manifestations and treatment of drug induced hepatotoxicity; Pathological manifestations of drug induced hepatotoxicity; Drug induced cholestasis; Lipid lowering agents induced hepatotoxicity; Herbal ,complementary and alternative medicine induced liver injury; Antiretroviral and anti - HCV DAA related hepatotoxicity; Antibiotic related hepatotoxicity; Acetaminophen related hepatoxicity; NSAIDS induced hepatoxocity; Chemotherapy induced hepatotoxicity; Anti epileptic induced hepatotoxicity; and steatohepatitis induced by drugs.

Hépatotoxicité médicamenteuse

Hépatotoxicité médicamenteuse PDF Author: Jean-Paul Fillastre
Publisher: Presses universitaires de Rouen et du Havre
ISBN: 9782877757218
Category : Medical
Languages : en
Pages : 348

Book Description
Ce volume rassemble les textes des communications faites lors du symposium organisé à Rouen les 23 et 24 mai 1985. Au cours de ce colloque sur l'hépatotoxicité, les sujets suivants ont été abordés : les aspects chimiques et anatomopathologiques des hépatites aiguës et chroniques d'origine médicamenteuse, les méca¬nismes d'action (qui ont occupé la plus grande partie de ces communications), les mécanismes de protection cellulaire vis-à-vis de certains métabolites toxiques, la quantification de la toxicité hépatique... Il est impossible de tout citer mais il est certain que l'ouvrage constitue un excellent document de travail pour tous ceux qui sont préoccupés par ce problème de l'hépatotoxicité tant expérimentale qu'humaine.

Assessment of the Risk of Hepatotoxicity with Kava Products

Assessment of the Risk of Hepatotoxicity with Kava Products PDF Author: World Health Organization
Publisher: WHO Regional Office Europe
ISBN: 9789241595261
Category : Medical
Languages : en
Pages : 92

Book Description
There has been international concern over the association of kava products and serious hepatotoxicity. Regulatory action banning these products in Europe has been controversial. The objective of this report is to investigate the possibility of hepatotoxicity with kava. It contains a description of kava and provides safety information as well as information on regulatory issues, conclusions and recommendations by the Committee appointed to handle this enquiry.

Liver Cells and Drugs

Liver Cells and Drugs PDF Author: André Guillouzo
Publisher: John Libbey Eurotext
ISBN: 9780861961283
Category : Medical
Languages : en
Pages : 520

Book Description
This book contains the 17 lectures given at the International Symposium on Liver Cells and Drugs held in Rennes on 7 to 10 July 1987 as well as 50 communications presented at the poster sessions.

Dictionary of Medicine

Dictionary of Medicine PDF Author: Svetolik P. Djordjević
Publisher: Schreiber, Shengold Publishing
ISBN: 1887563849
Category : English language
Languages : en
Pages : 1120

Book Description
With over 105,000 medical terms and over one million words, this is the most extensive dictionary of its kind available.

Hepatobiliary Diseases

Hepatobiliary Diseases PDF Author: Jesus Prieto
Publisher: Springer Science & Business Media
ISBN: 3642768024
Category : Medical
Languages : en
Pages : 1132

Book Description
The last few years have witnessed major developments in molecular biology which have had a significant impact on biomedical knowledge. As a result new concepts in cell biology have emerged, new etiologic agents have been discovered, and new drugs have become available. Furthermore, the world of mediators, cytokines, and humoral factors has enlarged considerably in a relatively short period and this has modified our views of diverse physio pathologic processes as well as opened up new therapeutic prospects. In addition, recent technologic advances have revolutionized our diagnostic methodology and have greatly enhanced the power of our therapeutic resources. All these factors have contributed to a substantial remodeling of both liver science and clinical hepatology, and these changes have generated the motivation for the production of the present book, which attempts to give an account of well-known clinical facts in the light of current thinking. It is the fruit of the coordinated work of experts from different countries in three continents. In a sense, it is a manifestation of the fact that inter national cooperation is becoming increasingly important not only in the expansion of science but also in its exposition. We hope that Hepatobiliary Diseases will be useful to both students and clinicians and that internists, gastroenterologists, and general practitioners will find in its contents a satifactory coverage of their field of interest.

Meyler's Side Effects of Drugs

Meyler's Side Effects of Drugs PDF Author: Jeffrey K. Aronson
Publisher: Elsevier
ISBN: 0444537163
Category : Medical
Languages : en
Pages : 7629

Book Description
Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Sixteenth Edition, Seven Volume Set builds on the success of the 15 previous editions, providing an extensively reorganized and expanded resource that now comprises more than 1,500 individual drug articles with the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive references to the primary literature, making this a must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company. The online version of the book provides an unparalleled depth of coverage and functionality by offering convenient desktop access and enhanced features such as increased searchability, extensive internal cross-linking, and fully downloadable and printable full-text, HTML or PDF articles. Enhanced encyclopedic format with drug monographs now organized alphabetically Completely expanded coverage of each drug, with more than 1,500 drug articles and information on adverse reactions and interactions Clearer, systematic organization of information for easier reading, including case histories to provide perspective on each listing Extensive bibliography with over 40,000 references A must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company

The Liver

The Liver PDF Author: Ch. Rouiller
Publisher: Academic Press
ISBN: 1483271765
Category : Medical
Languages : en
Pages : 689

Book Description
The Liver: Morphology, Biochemistry, Physiology, Volume II provides a comprehensive information on the liver under normal and pathological conditions, as revealed by physiological and morphological studies. This book discusses the excretory function of the liver cell, the physiology of the Kupffer cells, and the link of the liver with endocrine organs, blood, and vitamins. Organized into 15 chapters, this book begins with an overview of the formation and excretion of bile acids. This text then examines the various aspects associated with liver regeneration. Other chapters describe the liver function tests and the methods of experimental surgery. This book discusses as well the pathological changes responsible for the bleeding tendency of patients with liver disease. The final chapter deals with the general and experimental pathology of the organ and its regeneration, as well as with the problem of necrotropic substances. This book is a valuable resource for biochemists, pharmacologists, morphologists, and clinicians.