Author: A. R. MattocksPublisher:
ISBN:
Category : Medical
Languages : en
Pages : 424
Book Description
Chemistry and Toxicology of Pyrrolizidine Alkaloids
Author: A. R. MattocksPublisher:
ISBN:
Category : Medical
Languages : en
Pages : 424
Book Description
Analysis of Food Toxins and Toxicants, 2 Volume Set
Author: Yiu-Chung WongPublisher: John Wiley & Sons
ISBN: 1118992725
Category : Technology & Engineering
Languages : en
Pages : 790
Book Description
Analysis of Food Toxins and Toxicants consists of five sections, providing up-to-date descriptions of the analytical approaches used to detect a range of food toxins. Part I reviews the recent developments in analytical technology including sample pre-treatment and food additives. Part II covers the novel analysis of microbial and plant toxins including plant pyrrolizidine alkaloids. Part III focuses on marine toxins in fish and shellfish. Part IV discusses biogenic amines and common food toxicants, such as pesticides and heavy metals. Part V summarizes quality assurance and the recent developments in regulatory limits for toxins, toxicants and allergens, including discussions on laboratory accreditation and reference materials.
Pyrrolizidine Alkaloids
Author: Helmut WiedenfeldPublisher: Vandenhoeck & Ruprecht
ISBN: 3899714261
Category : Pyrrolizidines
Languages : de
Pages : 145
Book Description
Pyrrolizidine alkaloids show only minor toxicity in their native state, but are metabolized in the human or animal organisms to carcinogenic, teratogenic and mutagenic compounds, with the precise structure of these compounds being responsible for the metabolic toxification process. Therefore, to be able to evaluate the toxic potential of each alkaloid, it is essential to exactly know the structure of the respective compound. X-ray structure analysis is the appropriate method both for elucidating the structure and for determining other parameters, such as the lengths of the bonds that influence the metabolic process. This book describes the incidence and the process of the intoxication as well as the possibilities to how the substances may reach the organism. In addition, the compounds elucidated by X-ray structure analysis to date are shown in their three-dimensional structure and structure-toxicity relationships are discussed.Pyrrolizidinalkaloide weisen in nativem Zustand nur geringe Toxizität auf, werden jedoch zu kanzerogenen, teratogenen und mutagenen Verbindungen metabolisiert, wenn sie in den menschlichen oder tierischen Organismus gelangen. Der Verlauf dieser Toxifizierung hängt von der konkreten Struktur dieser Stoffe und weiteren Parametern ab. Zur Bestimmung dieser Faktoren stellt die Röntgenstrukturanalyse die geeignete Methode dar. Im vorliegenden Buch werden das Vorkommen, der Ablauf der Toxifizierung und die Möglichkeiten, wie die Stoffe in den Organismus gelangen können, beschrieben. Es werden die bislang durch Röntgenstrukturanalyse vermessenen Verbindungen in ihrer 3D-Struktur aufgefÃ"hrt und Struktur-Toxizitätsbeziehungen diskutiert.
Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose
Author: Michael W. ShannonPublisher: Saunders
ISBN: 9780721606934
Category : Drugs
Languages : en
Pages : 0
Book Description
This edition is a reference for information related to the clinical management of children and adults whose health has been effected or potentially effected by toxic agents, including drugs, environmental threats, and natural toxins.
The Pyrrolizidine Alkaloids
Author: L. B. BullLiver Disease in Children
Author: Frederick J. SuchyPublisher: Cambridge University Press
ISBN: 1108911374
Category : Medical
Languages : en
Pages : 875
Book Description
Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.
Drug-Induced Liver Injury
Author: Publisher: Academic Press
ISBN: 0128173173
Category : Medical
Languages : en
Pages : 288
Book Description
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
In Vitro Metabolism of Hepatotoxic Pyrrolizidine Alkaloids
Author: Ina GeburekNutritional Management of Equine Diseases and Special Cases
Author: Bryan M. WaldridgePublisher: John Wiley & Sons
ISBN: 1119191874
Category : Medical
Languages : en
Pages : 205
Book Description
Nutritional Management of Equine Diseases and Special Cases offers a concise, easy-to-comprehend text for equine veterinarians with questions about commonly encountered nutritional problems. Assists veterinarians in supporting equine patients with special nutritional needs Focuses on nutritional problems and impact on different body systems Covers ponies, miniature horses, draft horses, donkeys, and mules Offers complete coverage of common diseases and problems helped by nutrition Includes useful chapters on poisonous plants and mycotoxins
Drug-Induced Liver Disease
Author: Neil KaplowitzPublisher: CRC Press
ISBN: 0203909127
Category : Medical
Languages : en
Pages : 790
Book Description
Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.