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Author: G. di Prisco Publisher: Springer Science & Business Media ISBN: 8847021111 Category : Science Languages : en Pages : 140
Book Description
This volume comprises selected contributions by internationally renowned researchers and represents the state-of-the-art in the field of hemoglobin function in vertebrates living in extreme and temperate environments. The topics have been covered from several viewpoints, including protein chemistry, molecular biology, and evolution. All the contributions chosen for publication focus on phenotypic and genetic adaptations to changing environmental conditions and on gene expression and regulation. The book provides the reader with an update in this field, which is presently enjoying a true renaissance following developments in recent years of powerful methodologies such as site-directed mutagenesis and discoveries of new roles, for example, as oxygen sensors and in nitric oxide metabolism.
Author: G. di Prisco Publisher: Springer Science & Business Media ISBN: 8847021111 Category : Science Languages : en Pages : 140
Book Description
This volume comprises selected contributions by internationally renowned researchers and represents the state-of-the-art in the field of hemoglobin function in vertebrates living in extreme and temperate environments. The topics have been covered from several viewpoints, including protein chemistry, molecular biology, and evolution. All the contributions chosen for publication focus on phenotypic and genetic adaptations to changing environmental conditions and on gene expression and regulation. The book provides the reader with an update in this field, which is presently enjoying a true renaissance following developments in recent years of powerful methodologies such as site-directed mutagenesis and discoveries of new roles, for example, as oxygen sensors and in nitric oxide metabolism.
Author: Mikko Nikinmaa Publisher: Springer Science & Business Media ISBN: 3642839096 Category : Science Languages : en Pages : 273
Book Description
This book reviews the respiratory function of vertebrate red cells. I have defined the phrase "respiratory function" broadly to include, in addition to the actual oxygen and carbon dioxide transport, erythropoiesis, haemoglobin synthesis, red cell structure, the deformability of red cells in circulation, ion and substrate transport across the cell membrane, cellular metabolism, and control of cellular volume and pH. All of these aspects of the red cell function may affect gas transport between the respiratory epithelia and the tissues. Throughout the book, I have tried to relate our current knowledge about the nucleated red cell function to the wealth of information about the function of mammalian red cells. However, whenever possible, I have placed the emphasis on the nucleated red cell function for two reasons. First, the erythro cytes of 90% of vertebrate species are nucleated, and, second, nucleated red cell function has not been reviewed earlier in a single volume. This being the case, I have tried to make the reference list as complete as I could with regard to nucleated red cells. I hope that the approach adopted is useful for both com parative and human physiologists. Many people have contributed to the making of this book directly or in directly. Antti Soivio started me in this field. Prof. Henrik Wallgren has always encouraged fresh scientific ideas in his department. My present ideas of red cell function have been influenced by work carried out with Prof. Roy E.
Author: Roland N. Pittman Publisher: Biota Publishing ISBN: 1615047212 Category : Medical Languages : en Pages : 117
Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author: Pater W. Hochachka Publisher: Princeton University Press ISBN: 1400855411 Category : Science Languages : en Pages : 559
Book Description
This book discusses biochemical adaptation to environments from freezing polar oceans to boiling hot springs, and under hydrostatic pressures up to 1,000 times that at sea level. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Author: Ulrich Hoeger Publisher: Springer Nature ISBN: 3030417697 Category : Science Languages : en Pages : 527
Book Description
This book focuses on respiratory proteins, the broad hemoglobin family, as well as the molluscan and arachnid hemocyanins (and their multifunctional roles). Featuring 20 chapters addressing invertebrate and vertebrate respiratory proteins, lipoproteins and other body fluid proteins, and drawing on the editors’ extensive research in the field, it is a valuable addition to the Subcellular Biochemistry book series. The book covers a wide range of topics, including lipoprotein structure and lipid transport; diverse annelid, crustacean and insect defense proteins; and insect and vertebrate immune complexes. It also discusses a number of other proteins, such as the hemerythrins; serum albumin; serum amyloid A; von Willebrand factor and its interaction with factor VIII; and C-reactive protein. Given its scope, the book appeals to biologists, biomedical scientists and clinicians, as well as advanced undergraduates and postgraduates in these disciplines. Available as a printed book and also as an e-book and e-chapters, the fascinating material included is easily accessible.
Author: J. Neuwirt Publisher: Springer Science & Business Media ISBN: 9401010900 Category : Medical Languages : en Pages : 204
Book Description
Haemoglobin is one of the most important molecules in the animal kingdom. Its function is to carry oxygen to tissues. In lower invertebrates the blood pigment is present in the haemolymph and is not bound in cells. Later in the course of phylo genesis haemoglobin remains associated with cells which produce it and in this form it reaches the peripheral circulation. In higher organisms the haemoglobin production is thus determined by two main factors: haemoglobin synthesis in erythroid cells and the formation of these erythroid cells which depends on cell proliferation in haematopoietic organs. Human haemoglobin is made up of two chains which combine from four different polypeptide chains formed in varying ratios in different periods of the life cycle. During the life span of humans the following haemoglobins are formed: embryonic haemoglobins Gower 1 and 2, foetal haemoglobin F and two adult haemoglobins A and A . E-and IX-chains are part of the embryonic haemoglobins Gower 1 (E4) and 2 Gower 2 (1X2E2). These haemoglobins predominate in embryos during the second month of pregnancy and at the end of the first trimester they are completely re placed by foetal haemoglobin F (~Y2). Adult haemoglobin A consists of two IX and two ~-chains and is the main component of red cells in adults. A relatively small component of red cells accounting for less than 2 % of the total haemo globin, is haemoglobin A2 (1X0).
Author: Jean Lamy Publisher: Springer Science & Business Media ISBN: 3642706169 Category : Science Languages : en Pages : 186
Book Description
This volume is one of those published from the proceedings of the invited lectures to the First International Congress of Comparative Physiology and Biochemistry I organized at LI~e (Belgium) in August 1984 under the auspices of the Section of Comparative of the International Union of Biological Sciences. In a Physiology and Biochemistry general foreword to these different volumes, it seems to me appropriate to consider briefly what may be the comparative approach. Living organisms, beyond the diversity of their morphological forms, have evolved a widespread range of basic solutions to cope with the different problems, both organisma! and environmental, with which they are faced. Soon after the turn of the century, some biologists realized that these solutions can be best comprehended In the framework of a comparative approach integrating results of phYSiological and biochemical studies done at the organismic, cellular and molecular levels. The development of this approach amongst both physiologists and biochemists remained, however, extremely slow until recently.
Author: G. di Prisco
Author: G. di Prisco
Author: Mikko Nikinmaa
Author: Roland N. Pittman
Author: Martha C. Farmer
Author: Pater W. Hochachka
Author: Ulrich Hoeger
Author: Richard Earl Dickerson
Author: J. Neuwirt
Author: Jean Lamy
Author: Martin H. Steinberg