On-Line Hemodiafiltration: The Journey and the Vision PDF Download

Author: G. Krick
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805599072
Category : Medical
Languages : en
Pages : 202

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Book Description
On-line HDF represents a major technical development in the delivery of hemodialysis therapy: It combines the properties of increased diffusion available in current high-flux membranes with convective removal of between 6 and 30 liters per treatment and requires the use of ultrapure water and online filtration of replacement fluid. On-line HDF has been successfully introduced in Europe and Asia and is routinely prescribed for dialysis patients in these regions.The book at hand summarizes the history and achievements of on-line HDF in four parts: A report of the technological development in both machine and fiber/dialyzer is followed by a description of the challenges encountered in the evolution of on-line HDF, collecting the accounts of clinical key opinion leaders who had been involved in its early application. The third part presents a comprehensive review of the clinical results achieved with on-line HDF from its inception to the present times, in which it represents the clinical golden standard. The fourth and final part is dedicated to on-line HDF as a ‘vision’ for the future.

Author: John A. Kellum
Publisher: Oxford University Press
ISBN: 019022553X
Category : Medical
Languages : en
Pages : 329

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Book Description
Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.

Author: Claudio Ronco
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805582889
Category : Medical
Languages : en
Pages : 249

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Book Description
A concise handbook on clinical and technical possibilities The application of hemodiafiltration has been restricted until recently, when a broader clinical application has been made possible due to evidence from large studies and clinical investigations. This book provides an updated review of the evolution, advances and recent results achieved by hemodiafiltration in the clinical arena. The first part is devoted to historical notes and an outline of the evolution of different forms of hemodiafiltration, made possible by technological developments in the fields of membranes, machines and fluids. The next section describes the theoretical rationale for hemodiafiltration, providing a detailed analysis of the involved mass separation processes, the hydraulic properties of the dialyzers, fluid mechanics and crossfiltration in hollow fiber hemodialyzers. An outline of different hemodiafiltration techniques, also reporting peculiar transport mechanisms and related technology, is given next, and a section on the clinical effects of hemodiafiltration concludes this book. Including different technologies, the publication offers a complete overview of the technical and clinical possibilities provided by hemodiafiltration in its widest concept, ranging from the molecular basis to the most practical application. It will be a valuable tool for the implementation of hemodiafiltration in daily practice aimed at beginners and experts, scientists and physicians, students and senior faculty members alike.

Author: Menso J. Nubé
Publisher: Springer
ISBN: 3319233327
Category : Medical
Languages : en
Pages : 346

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Book Description
This book gives a complete description of online hemodiafiltration, in five sections. It is unique in the systematic and complete way in which hemodiafiltration is described. Each chapter is completed by a point-to-point summary of essential information, in a separate text box. Part of the book is dedicated to the theoretical background of convective clearance. In this part, safety issues and quality control is reviewed (especially on the quality of water for dialysis and substitution fluid), as well as equipment (both dialyzers and machines) with which this treatment can be performed. As recently the results of several randomized controlled trials were available, the effect of hemodiafiltration on hard clinical end points (mortality and morbidity) is discussed in detail. This has not been done before, as the most recent book/journal on hemodiafiltration was published in 2011, before the results of the 3 randomized controlled trials were published. Furthermore, the methodological quality of the trials is discussed by an expert, in order to help the readers in their judgment of the trials Part of the book concentrates on the effect of the treatment on several biomarkers and uremic toxins. Several clinically relevant issues is discussed separately, such as the prescription of anticoagulation during the treatment, drug prescription and clearance for patients treated with hemodiafiltration, and hemodynamic stability. Finally, a practical guide on how to perform the treatment is provided. In this unique section, seemingly simple but important details of hemodiafiltration-treatment is discussed, such as the importance of needle size for blood flow rates, the difference between filtration fraction and substitution ratio, the different targets that can be set and how to reach them. As most literature is mainly focused on theoretical issues, this unique feature really will help the field to perform hemodiafiltration, and answer practical questions.

Author: John T. Daugirdas
Publisher: Lippincott Williams & Wilkins
ISBN: 1451165919
Category : Medical
Languages : en
Pages : 806

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Book Description
The revised, updated Fourth Edition of this popular handbook provides practical, accessible information on all aspects of dialysis, with emphasis on day-to-day management of patients. Chapters provide complete coverage of hemodialysis, peritoneal dialysis, special problems in dialysis patients, and problems pertaining to various organ systems. This edition reflects the latest guidelines of the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQI) on hemodialysis and peritoneal dialysis adequacy and on nutrition. New chapters cover chronic kidney disease management in predialysis patients, frequent daily or nocturnal hemodialysis, and hemodiafiltration. Chapters on venous and arteriovenous access have been completely revised. Each chapter provides references to relevant Web sites.

Author: C. Ronco
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318061174
Category : Medical
Languages : en
Pages : 216

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Book Description
Despite constant significant advances, cardiovascular as well as more general outcomes of hemodialysis treatment remain unsatisfactory. The introduction of innovative 'high retention onset' membranes has led to the development of a new treatment modality called 'expanded hemodialysis' (HDx), which is the focus of this book. This new therapy is likely to benefit end-stage kidney disease patients, thanks to enhanced removal of molecules retained by current dialysis techniques. HDx is simple to set up and application does not require special hardware or specific nursing skills. This book contains emerging evidence and fascinating new hypotheses on HDx. It is highly recommended for all physicians and healthcare professionals who are caring for dialysis patients and are seeking innovation and improved care solutions. It will also be of considerable interest to students and fellows.

Author: Claudio Ronco
Publisher: Elsevier Health Sciences
ISBN: 0323511996
Category : Medical
Languages : en
Pages : 1843

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Book Description
Comprehensive and clinically relevant, the 3rd Edition of Critical Care Nephrology provides authoritative coverage of the latest advances in critical care procedures for patients with renal diseases or disorders. Using common guidelines and standardized approaches to critically ill patients, this multidisciplinary reference facilitates better communication among all physicians who care for critically ill patients suffering from kidney disease, electrolyte and metabolic imbalances, poisoning, severe sepsis, major organ dysfunction, and other pathological events. - Offers detailed discussions of different forms of organ support, artificial organs, infections, acute illness occurring in chronic hemodialysis patients, and much more. - Places a special emphasis on therapeutic interventions and treatment procedures for a hands on clinical reference tool. - Presents information clearly, in a format designed for easy reference – from basic sciences to clinical syndromes to diagnostic tools. - Covers special populations such as children, diabetic patients, and the elderly. - An exceptional resource for nephrologists, intensivists, surgeons, or critical care physicians – anyone who treats critically ill renal patients. - Shares a combined commitment to excellence lead by Drs. Claudio Ronco, Rinaldo Bellomo, John Kellum, and Zaccaria Ricci – unparalleled leaders in this field. - Addresses key topics with expanded coverage of acute kidney injury, stress biomarkers, and sepsis, including the latest developments on mechanisms and management. - Provides up-to-date information on extracorporeal therapies from new editor Dr. Zaccaria Ricci. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Author: E. Streicher
Publisher: S. Karger AG (Switzerland)
ISBN:
Category : Medical
Languages : en
Pages : 204

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Book Description

Author: Leszek Pstras
Publisher: Springer
ISBN: 3030214109
Category : Medical
Languages : en
Pages : 166

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Book Description
Beginning with an introduction to kidney function, renal replacement therapies, and an overview of clinical problems associated with haemodialysis, this book explores the principles of the short-term baroreflex regulation of the cardiovascular system and the mechanisms of water and solute transport across the human body from a mathematical model perspective. It synthesizes theoretical physiological concepts and practical aspects of mathematical modelling needed for simulation and quantitative analysis of the haemodynamic response to dialysis therapy. Including an up-to-date review of the literature concerning the modelled physiological mechanisms and processes, the book serves both as an overview of transport and regulatory mechanisms related to the cardiovascular system and body fluids and as a useful reference for the study and development of mathematical models of dynamic physiological processes. Mathematical Modelling of Haemodialysis: Cardiovascular Response, Body Fluid Shifts, and Solute Kinetics is intended for researchers and graduate students in biomedical engineering, physiology, or medicine interested in mathematical modelling of cardiovascular dynamics and fluid and solute transport across the human body, both under physiological conditions and during haemodialysis therapy.

Author: William L. Henrich
Publisher: Lippincott Williams & Wilkins
ISBN: 1451148720
Category : Medical
Languages : en
Pages : 730

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Book Description
This book is an evidence-based review of the practical challenges of dealing with patients receiving dialysis. The first section covers technical and procedural considerations such as choosing the hemodialysis membrane and choosing the best dialysis option. The second section covers clinical considerations such as infection and the treatment of specific renal disease complications. The book includes numerous illustrations and tables and drug charts for dialysis patients. This edition's current outcomes chapter has been expanded to include patient depression and improving quality of care. New chapters cover dialysis in the ICU, valvular heart disease, and pre-emptive renal transplantation.