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Heart rate as a determinant of cardiac function

Heart rate as a determinant of cardiac function PDF Author: G. Hasenfuss
Publisher: Springer Science & Business Media
ISBN: 364247070X
Category : Medical
Languages : en
Pages : 464

Book Description
In a variety of cardiac diseases the influence of heart rate on cardiac function is altered and both heart rate and heart rate variability are of great relevance for the prognosis of cardiac patients. This book provides a summary of the current knowledge on the influence of heart rate on myocardial function and hemodynamics in non-failing and failing animal and human hearts. The subcellular and molecular alterations underlying the altered heart rate response in heart failure are discussed in detail. In addition, studies related to the impact of heart rate and heart rate variability on arrhythmogenesis and prognosis in patients with cardiac diseases are critically reviewed. Finally, the relevance of heart rate control by therapeutic interventions is also discussed. The book contains 19 different chapters written by well-known experts in this novel and clinically important field.

Heart rate as a determinant of cardiac function

Heart rate as a determinant of cardiac function PDF Author: G. Hasenfuss
Publisher: Springer Science & Business Media
ISBN: 364247070X
Category : Medical
Languages : en
Pages : 464

Book Description
In a variety of cardiac diseases the influence of heart rate on cardiac function is altered and both heart rate and heart rate variability are of great relevance for the prognosis of cardiac patients. This book provides a summary of the current knowledge on the influence of heart rate on myocardial function and hemodynamics in non-failing and failing animal and human hearts. The subcellular and molecular alterations underlying the altered heart rate response in heart failure are discussed in detail. In addition, studies related to the impact of heart rate and heart rate variability on arrhythmogenesis and prognosis in patients with cardiac diseases are critically reviewed. Finally, the relevance of heart rate control by therapeutic interventions is also discussed. The book contains 19 different chapters written by well-known experts in this novel and clinically important field.

Heart Rate as a Determinant of Cardiac Function

Heart Rate as a Determinant of Cardiac Function PDF Author: Gerd Hasenfuss
Publisher:
ISBN:
Category : Cardiac output
Languages : en
Pages : 0

Book Description


Heart rate as a determinant of cardiac function

Heart rate as a determinant of cardiac function PDF Author: Gerd Hasenfuß
Publisher:
ISBN:
Category :
Languages : de
Pages : 159

Book Description


Heart Rate as a Determinant of Cardiac Function

Heart Rate as a Determinant of Cardiac Function PDF Author:
Publisher:
ISBN:
Category : Angiotensins
Languages : en
Pages : 159

Book Description


Control of Cardiac Output

Control of Cardiac Output PDF Author: David Young
Publisher: Biota Publishing
ISBN: 1615040226
Category : Medical
Languages : en
Pages : 110

Book Description
Although cardiac output is measured as the flow of blood from the left ventricle into the aorta, the system that controls cardiac output includes many other components besides the heart itself. The heart’s rate of output cannot exceed the rate of venous return to it, and therefore, the factors governing venous return are primarily responsible for control of output from the heart. Venous return is affected by its pressure gradient and resistance to flow throughout the vascular system. The pressure gradient for venous return is a function of several factors including the blood volume flowing through the system, the unstressed vascular volume of the circulatory system, its capacitance, mean systemic pressure, and right atrial pressure. Resistance to venous return is the sum of total vascular resistance from the aortic valve to the right atrium. The sympathetic nervous system and vasoactive circulating hormones affect short-term resistance, whereas local tissue blood flow autoregulatory mechanisms are the dominant determinants of long-term resistance to venous return. The strength of contraction of the heart responds to changes in atrial pressure driven by changes in venous return, with small changes in atrial pressure eliciting large changes in strength of contraction, as described by the Frank–Starling mechanism. In addition, the autonomic nervous system input to the heart alters myocardial pumping ability in response to cardiovascular challenges. The function of the cardiovascular system is strongly affected by the operation of the renal sodium excretion–body fluid volume–arterial pressure negative feedback system that maintains arterial blood pressure at a controlled value over long periods. The intent of this volume is to integrate the basic knowledge of these cardiovascular system components into an understanding of cardiac output regulation. Table of Contents: Introduction / Venous Return / Cardiac Function / Integrated Analysis of Cardiac Output Control / Analysis of Cardiac Output Regulation by Computer Simulation / Analysis of Cardiac Output Control in Response to Challenges / Conclusion / References / Author Biography

Regulation of Coronary Blood Flow

Regulation of Coronary Blood Flow PDF Author: Michitoshi Inoue
Publisher: Springer Science & Business Media
ISBN: 4431683674
Category : Medical
Languages : en
Pages : 330

Book Description
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

Fluid Resuscitation

Fluid Resuscitation PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309172799
Category : Medical
Languages : en
Pages : 207

Book Description
Historically, 20% of all injured combatants die on the battlefield before they can be evacuated to a field hospital. Blood lossâ€"hemorrhageâ€"is the single major cause of death among those killed in action whose lives might otherwise be saved. Fluid resuscitation and the treatment of hypovolemia (the abnormally decreased volume of circulating fluid in the body) offer the greatest opportunity for reducing mortality and morbidity associated with battlefield casualties. In Fluid Resuscitation, a committee of experts assess current resuscitation fluids and protocols for the treatment of combat casualties and make recommendations for future research. Chapters focus on the pathophysiology of acute hemorrhagic shock, experience with and complications of fluid resuscitation, novel approaches to the treatment of shock, protocols of care at the site of injury, and future directions for research. The committee explicitly describes the similarities and differences between acute medical care during combat and civilian emergency trauma care. Fluid Resuscitation should help energize and focus research in both civilian and military emergency care and help save the lives of citizens and soldiers alike.

Gross Physiology of the Cardiovascular System

Gross Physiology of the Cardiovascular System PDF Author: Robert Anderson
Publisher: Lulu.com
ISBN: 1105522237
Category : Science
Languages : en
Pages : 72

Book Description
A groundbreaking, global overview of the mechanical function of the cardiovascular system, as featured at the http://cardiac-output.info website. This text explains fundamental but often misunderstood concepts, such as: the unique hydraulic characteristics of the heart as a pump and the cardiovascular system; the determinants of cardiac output; the mechanism that maintains blood volume equilibrium between the systemic and pulmonary circuits; and the primary contribution of the atria to circulation rate.Distilled from decades of research and surgical experience by Dr. Robert M. Anderson -- a pioneer heart surgeon, biomedical inventor, award-winning professor, and former Associate Dean of the University of Arizona College of Medicine -- the text is a far more explanatory and predictive account than the conventional model featured in many basic physiology textbooks (with its often misleading focus on incomplete parameters such as preload, afterload, contractility, and stroke rate times stroke volume).

Comprehensive Electrocardiology

Comprehensive Electrocardiology PDF Author: Peter W. Macfarlane
Publisher: Springer Science & Business Media
ISBN: 1848820453
Category : Medical
Languages : en
Pages : 2310

Book Description
New edition of the classic complete reference book for cardiologists and trainee cardiologists on the theory and practice of electrocardiography, one of the key modalities used for evaluating cardiology patients and deciding on appropriate management strategies.

Hemodynamic Monitoring

Hemodynamic Monitoring PDF Author: Michael R. Pinsky
Publisher: Springer
ISBN: 3319692690
Category : Medical
Languages : en
Pages : 476

Book Description
This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.