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Public Health Risk Assessment for Human Exposure to Chemicals

Public Health Risk Assessment for Human Exposure to Chemicals PDF Author: K. Asante-Duah
Publisher: Springer Science & Business Media
ISBN: 9401004811
Category : Medical
Languages : en
Pages : 352

Book Description
In fact, with the control and containment of most infectious conditions and diseases of the past millennium having been achieved in most developed countries, and with the resultant increase in life expectancies, much more attention seems to have shifted to degenerative health problems. Many of the degenerative health conditions have been linked to thousands of chemicals regularly encountered in human living and occupational/work environments. It is important, therefore, that human health risk assessments are undertaken on a consistent basis - in order to determine the potential impacts of the target chemicals on public health.

Public Health Risk Assessment for Human Exposure to Chemicals

Public Health Risk Assessment for Human Exposure to Chemicals PDF Author: K. Asante-Duah
Publisher: Springer Science & Business Media
ISBN: 9401004811
Category : Medical
Languages : en
Pages : 352

Book Description
In fact, with the control and containment of most infectious conditions and diseases of the past millennium having been achieved in most developed countries, and with the resultant increase in life expectancies, much more attention seems to have shifted to degenerative health problems. Many of the degenerative health conditions have been linked to thousands of chemicals regularly encountered in human living and occupational/work environments. It is important, therefore, that human health risk assessments are undertaken on a consistent basis - in order to determine the potential impacts of the target chemicals on public health.

Health Risk Assessment of Environmental Chemicals

Health Risk Assessment of Environmental Chemicals PDF Author: Masami Ishido
Publisher: Springer
ISBN: 9789819915590
Category : Medical
Languages : en
Pages : 0

Book Description
This book presents the frontier research of toxicology and health risk assessment of chemicals. First, it provides an overview of the current methods of evaluating safety amounts of chemicals and provides a new aspect of the principle of toxicology. Secondly, it shows recent research where the new method of health risk evaluation is adopted, followed by an integrated health risk assessment of chemicals. Finally, it describes the epigenetic inheritance of chemical impact on health throughout several generations. Estimating the safety amount of chemicals surrounding our lives is not sufficient for health risk evaluation, particularly for carcinogenic compounds, endocrine disruptors, and nano materials. The author’s group has found a family of chemicals linked to ADHD through animal screening and identified its chemical nature using chemoinformatics methods. Based on these new developments, this book proposes to utilize the biomarker common to those chemicals for health risk assessment, independent of exposure routes and physiological dimensions. The book appeals to researchers and students in the field of toxicology, health risk assessment, pharmacology, and public health.

Phthalates and Cumulative Risk Assessment

Phthalates and Cumulative Risk Assessment PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309128412
Category : Nature
Languages : en
Pages : 208

Book Description
People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.

Environmental Chemicals, the Human Microbiome, and Health Risk

Environmental Chemicals, the Human Microbiome, and Health Risk PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309468698
Category : Science
Languages : en
Pages : 123

Book Description
A great number of diverse microorganisms inhabit the human body and are collectively referred to as the human microbiome. Until recently, the role of the human microbiome in maintaining human health was not fully appreciated. Today, however, research is beginning to elucidate associations between perturbations in the human microbiome and human disease and the factors that might be responsible for the perturbations. Studies have indicated that the human microbiome could be affected by environmental chemicals or could modulate exposure to environmental chemicals. Environmental Chemicals, the Human Microbiome, and Health Risk presents a research strategy to improve our understanding of the interactions between environmental chemicals and the human microbiome and the implications of those interactions for human health risk. This report identifies barriers to such research and opportunities for collaboration, highlights key aspects of the human microbiome and its relation to health, describes potential interactions between environmental chemicals and the human microbiome, reviews the risk-assessment framework and reasons for incorporating chemicalâ€"microbiome interactions.

Identifying and Reducing Environmental Health Risks of Chemicals in Our Society

Identifying and Reducing Environmental Health Risks of Chemicals in Our Society PDF Author: Robert Pool
Publisher:
ISBN: 9780309301152
Category : Health & Fitness
Languages : en
Pages : 0

Book Description
"On November 7-8, 2013, the Institute of Medicine's Roundtable on Environmental Health Sciences, Research, and Medicine held a workshop to discuss approaches related to identifying and reducing potential environmental public health risks to new and existing industrial chemicals present in society. Industrial chemicals include chemicals used in industrial processes or commercial products, not including those found in food, pesticides, or pharmaceuticals. Identifying and Reducing Environmental Health Risks of Chemicals in Our Society is a summary and synthesis of the presentations and discussions that took place during the two days of the workshop. The workshop examined successes and areas for improvement within current regulatory programs for assessing industrial chemical safety, frameworks for chemical prioritization to inform targeted testing and risk management strategies, concepts of sustainability and green chemistry that support the design and use of safer alternatives, and efforts to reduce the risk of chemicals in our society."--Publisher's description.

Science and Decisions

Science and Decisions PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309120462
Category : Political Science
Languages : en
Pages : 422

Book Description
Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Hazard Assessment Of Chemicals

Hazard Assessment Of Chemicals PDF Author: J. Saxena
Publisher: CRC Press
ISBN: 9781560322719
Category : Science
Languages : en
Pages : 348

Book Description
The majority of chapters in this volume are devoted to various aspects of health risk assessment the evaluation of health hazard associated with human risk exposure to environmental chemicals. Among topics discussed

Principles for Evaluating Health Risks in Children Associated with Exposure to Chemicals

Principles for Evaluating Health Risks in Children Associated with Exposure to Chemicals PDF Author: Germaine Buck Louis
Publisher: World Health Organization
ISBN: 924157237X
Category : Medical
Languages : en
Pages : 352

Book Description
Conclusions, and recommendations -- Introduction and background -- Unique biological characteristics of children -- Developmental stage-specific susceptibilities and outcomes in children -- Exposure assessment of children -- Methodologies to assess health outcomes in children -- Implications and strategies for risk assessment for children.

Exposure Assessment in Environmental Epidemiology

Exposure Assessment in Environmental Epidemiology PDF Author: Mark J. Nieuwenhuijsen
Publisher: Oxford University Press, USA
ISBN: 0199378789
Category : Medical
Languages : en
Pages : 417

Book Description
This completely updated edition of Exposure Assessment in Environmental Epidemiology offers a practical introduction to exposure assessment methodologies in environmental epidemiologic studies. In addition to methods for traditional methods -- questionnaires, biomonitoring -- this new edition is expanded to include geographic information systems, modeling, personal sensoring, remote sensing, and OMICs technologies. In addition, each of these methods is contextualized within a recent epidemiology study, maximizing illustration for students and those new to these to these techniques. With clear writing and extensive illustration, this book will be useful to anyone interested in exposure assessment, regardless of background.

Risk Assessment of Chemicals: An Introduction

Risk Assessment of Chemicals: An Introduction PDF Author: C.J. van Leeuwen
Publisher: Springer Science & Business Media
ISBN: 9401585202
Category : Science
Languages : en
Pages : 386

Book Description
In recent years many developments have taken place in promote co-operation between governments and other the field of risk assessment of chemicals. Many reports parties involved in chemical safety and to provide policy have been published by national authorities, industries guidance with emphasis on regional and subregional co and scientific researchers as well as by international bod operation. The Inter-Organization Programme for the ies such as the European Union, the Organization of Sound Management of Chemicals (IOMC) was estab Economic Cooperation and Development (OECD) and lished in 1995 and provides a mechanism for the six par the joint International Programme on Chemical Safety ticipating organizations (UNEP, ILO, FAO, UNIDO,WHO (IPCS) of the World Health Organization (WHO), the and OECD) to better co-ordinate policies and activities in International Labour Organization (lLO), and the United the field of chemical risk management. Nations Environment Programme (UNEP). The present book is an introduction to risk assessment of The development and international harmonization of risk chemicals. It contains basic background information on assessment methods is an important challenge. In sources, emissions, distribution and fate processes for Agenda 21 of the United Nations Conference on exposure estimation. It includes dose-effects estimation Environment and Development (UNCED), chapter 19 is for both human health related toxicology and ecotoxicol entirely devoted to the management of chemicals. For ogy as well as information on estimation methodologies. one of its recommendations, i. e.