Author: Roger W. Beuerman
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 264
Book Description
Healing Processes in the Cornea
Author: Roger W. Beuerman
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 264
Book Description
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 264
Book Description
The process of wound healing in the corneal epithelium
Author: William Marshall Covode
Publisher:
ISBN:
Category :
Languages : en
Pages : 72
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 72
Book Description
Wound Healing of the Ocular Surface
Experimental Corneal Alkali Wound Healing
Author: Jang-Hyun Chung
Publisher:
ISBN:
Category : Alkalies
Languages : en
Pages : 44
Book Description
Publisher:
ISBN:
Category : Alkalies
Languages : en
Pages : 44
Book Description
Biomechanics of Corneal Wound Healing
Author: James Charles Ramier
Publisher:
ISBN:
Category : Biomechanics
Languages : en
Pages : 160
Book Description
"The re-establishment of tissue continuity, function, and mechanical proper ties after a through-and-through incision is an important issue in corneal surgery and trauma. Variations in healing can affect vision and patient activity during the recovery period, which may last up to five years. Growth factors introduced into the open wound have the potential to speed up the wound-healing process. The current investigation is concerned with quantitatively characterizing the mechanical properties of corneal tissue and evaluating the effects of epidermal growth factor (EGF), insulin-like growth factor (IGF), and platelet-derived growth factor (PDGF) on accelerating the wound-healing process as compared to a control group treated with phosphate-buffered saline (PBS). A 30 day topical application period was employed to assess the influence of EGF, IGF, and PDGF versus PBS treated corneas following through-and-through incisions. Corneal test specimens were harvested at 3, 10, and 30 days postoperatively and subjected to uniaxial tension loading (perpendicular to the wound) with load and displacement values recorded. Gross strength properties of fracture toughness, peak tangent modulus, and peak stress were calculated and the stiffness characteristics of the test specimens were obtained through curve fitting of the stress - stretch ratio profile. Comparison of strength properties indicated that IGF application enhanced peak stress, tangent modulus, and fracture toughness at 3 and 10 days while EGF application produced dominant responses at 30 days. Stiffness characterization revealed enhanced stiffness with EGF at 3 and 30 days, while PDGF treatment showed dominant stiffness characteristics at 10 days. The results suggest that select growth factors may preferentially augment the time course of corneal wound healing."--Abstract.
Publisher:
ISBN:
Category : Biomechanics
Languages : en
Pages : 160
Book Description
"The re-establishment of tissue continuity, function, and mechanical proper ties after a through-and-through incision is an important issue in corneal surgery and trauma. Variations in healing can affect vision and patient activity during the recovery period, which may last up to five years. Growth factors introduced into the open wound have the potential to speed up the wound-healing process. The current investigation is concerned with quantitatively characterizing the mechanical properties of corneal tissue and evaluating the effects of epidermal growth factor (EGF), insulin-like growth factor (IGF), and platelet-derived growth factor (PDGF) on accelerating the wound-healing process as compared to a control group treated with phosphate-buffered saline (PBS). A 30 day topical application period was employed to assess the influence of EGF, IGF, and PDGF versus PBS treated corneas following through-and-through incisions. Corneal test specimens were harvested at 3, 10, and 30 days postoperatively and subjected to uniaxial tension loading (perpendicular to the wound) with load and displacement values recorded. Gross strength properties of fracture toughness, peak tangent modulus, and peak stress were calculated and the stiffness characteristics of the test specimens were obtained through curve fitting of the stress - stretch ratio profile. Comparison of strength properties indicated that IGF application enhanced peak stress, tangent modulus, and fracture toughness at 3 and 10 days while EGF application produced dominant responses at 30 days. Stiffness characterization revealed enhanced stiffness with EGF at 3 and 30 days, while PDGF treatment showed dominant stiffness characteristics at 10 days. The results suggest that select growth factors may preferentially augment the time course of corneal wound healing."--Abstract.
Wound Healing and the Diabetic Cornea
Author: Sherry Ann Fowler
Publisher:
ISBN:
Category : Diabetes
Languages : en
Pages : 284
Book Description
Publisher:
ISBN:
Category : Diabetes
Languages : en
Pages : 284
Book Description
The Biology of Corneal Grafts and the Healing Processes of Corneal Wounds
Neuropeptides and Neurotransmitters in Keratocytes
Analysis of Stem Cells and Wound Healing in the Human Cornea
Author: Chuan-Yuan Ally Chang
Publisher:
ISBN:
Category :
Languages : en
Pages : 240
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 240
Book Description
The Wound Healing Responses and Corneal Biomechanics After Keratorefractive Surgery
Author: Yan Wang
Publisher:
ISBN:
Category : Electronic books
Languages : en
Pages : 0
Book Description
Corneal biomechanics have been concerned recently since it is not only found to play an important role in the wound healing process after corneal refractive surgeries, but also essential to improve the predictability and safety of refractive procedures. Corneal biomechanics and wound healing responses are linked in time and space and may also cause complications of keratectasia, haze formation, and regression. This review focuses on wound healing and biomechanics of the corneal refractive procedures. Identifying corneal wound healing from the biomechanical point of view is mandatory to improve the outcomes and reduce the complications.
Publisher:
ISBN:
Category : Electronic books
Languages : en
Pages : 0
Book Description
Corneal biomechanics have been concerned recently since it is not only found to play an important role in the wound healing process after corneal refractive surgeries, but also essential to improve the predictability and safety of refractive procedures. Corneal biomechanics and wound healing responses are linked in time and space and may also cause complications of keratectasia, haze formation, and regression. This review focuses on wound healing and biomechanics of the corneal refractive procedures. Identifying corneal wound healing from the biomechanical point of view is mandatory to improve the outcomes and reduce the complications.