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Handbook of Methods in Gastrointestinal Pharmacology

Handbook of Methods in Gastrointestinal Pharmacology PDF Author: Timothy S. Gaginella
Publisher: CRC Press
ISBN: 9780849383045
Category : Medical
Languages : en
Pages : 468

Book Description
Gastroenterology has advanced through the development and application of increasingly sophisticated methods to measure changes in gastrointestinal function. Handbook of Methods in Gastrointestinal Pharmacology brings together details on commonly employed approaches in investigative gastroenterology. The book provides comprehensive coverage of methods and techniques used to investigate the mechanism of action of drugs on the GI tract. An integral part of each chapter is the discussion of development of techniques based upon physiologic mechanisms and principles in pharmacology. In vivo and in situ techniques involving whole animals, isolated tissue methodology, the use of single cell systems, and molecular biology approaches are covered. Illustrations provide a clear understanding of methodologies discussed. Emphasis is placed on advantages and disadvantages of each technique in answering specific research questions. Chapters are written by experts experienced in the techniques they discuss; many pioneered one or more widely used methods. The wide variety of topics included make the Handbook of Methods in Gastrointestinal Pharmacology useful to established investigators, research fellows, and graduate students. Additionally, reviewers of grants and manuscripts can use it to clarify questions that arise regarding appropriate use of a technique in a particular setting.

Handbook of Methods in Gastrointestinal Pharmacology

Handbook of Methods in Gastrointestinal Pharmacology PDF Author: Timothy S. Gaginella
Publisher: CRC Press
ISBN: 9780849383045
Category : Medical
Languages : en
Pages : 468

Book Description
Gastroenterology has advanced through the development and application of increasingly sophisticated methods to measure changes in gastrointestinal function. Handbook of Methods in Gastrointestinal Pharmacology brings together details on commonly employed approaches in investigative gastroenterology. The book provides comprehensive coverage of methods and techniques used to investigate the mechanism of action of drugs on the GI tract. An integral part of each chapter is the discussion of development of techniques based upon physiologic mechanisms and principles in pharmacology. In vivo and in situ techniques involving whole animals, isolated tissue methodology, the use of single cell systems, and molecular biology approaches are covered. Illustrations provide a clear understanding of methodologies discussed. Emphasis is placed on advantages and disadvantages of each technique in answering specific research questions. Chapters are written by experts experienced in the techniques they discuss; many pioneered one or more widely used methods. The wide variety of topics included make the Handbook of Methods in Gastrointestinal Pharmacology useful to established investigators, research fellows, and graduate students. Additionally, reviewers of grants and manuscripts can use it to clarify questions that arise regarding appropriate use of a technique in a particular setting.

Oxford Handbook of Gastrointestinal Nursing

Oxford Handbook of Gastrointestinal Nursing PDF Author: Christine Norton
Publisher: Oxford University Press, USA
ISBN: 0199298653
Category : Medical
Languages : en
Pages : 762

Book Description
"This practical guide to all aspects of gastrointestinal nursing covers the treatment of a wide range of patients - from those suffering from minor and acute disorders, through chronic conditions, to those requiring major surgery and treatment for malignant disease. It summarizes the current state of knowledge in gastrointestinal nursing and provides concise, user-friendly guidelines on the management and treatment of patients with gastrointestinal disorders." "Written by practising nurses and subject experts, and incorporating their years of experience, the Oxford Handbook of Gastrointestinal Nursing is a unique and invaluable companion for practising nurses, and for all health care professionals who are involved in the care of patients with gastrointestinal disorders."--BOOK JACKET.

Manual of Immunological Methods

Manual of Immunological Methods PDF Author: Canadian Networking
Publisher: CRC Press
ISBN: 9780849385582
Category : Medical
Languages : en
Pages : 164

Book Description
The Manual of Immunological Methods represents the collaboration of the Canadian Network of Toxicology Centers, a non-profit network of university-based scientists dedicated to research, training, risk assessment, and communication. This manual provides detailed immunological methods that can be utilized by researchers or practitioners who want to enhance the successful application of this science. It emphasizes the need for continuously improving the quality of experiments performed and maintaining consistency in the results obtained. The Manual of Immunological Methods presents validated assays that are accompanied by a series of tools that will guide readers in performing their own laboratory work in the spirit of the Good Laboratory Practices. It covers specific methodologies including sample collection, preparation of cells, assay conditions, and data evaluation. Discussion of species differences and comparisons of a wide variety of species is an important feature. Both graduate students and practicing researchers in the areas of immunology and immunotoxicology will appreciate the Manual of Immunological Methods as a guide to standard operating procedures in the laboratory.

Toxicology of the Gastrointestinal Tract, Second Edition

Toxicology of the Gastrointestinal Tract, Second Edition PDF Author: Shayne Cox Gad
Publisher: CRC Press
ISBN: 042978144X
Category : Medical
Languages : en
Pages : 477

Book Description
Nanoparticles as both potential unique risks and as a valuable approach to increased and higher specificity in delivery of therapeutics A primer on the largest, most diverse, and important microbiome in any mammal "Tricks of the trade" on modifying the oral administration of drugs

Oxford Handbook of Gastroenterology and Hepatology

Oxford Handbook of Gastroenterology and Hepatology PDF Author: Stuart Bloom
Publisher: Oxford University Press, USA
ISBN: 0199584079
Category : Medical
Languages : en
Pages : 658

Book Description
Written by experts within their fields, the handbook provides up-to-date, practical advice on the management of common conditions for trainees and specialists in gastroenterology and hepatology. It covers approaches to clinical problems, including infectious disease and gastrointestinal problems in developing countries.

Stealth Liposomes

Stealth Liposomes PDF Author: Danilo D. Lasic
Publisher: CRC Press
ISBN: 1351414011
Category : Medical
Languages : en
Pages : 324

Book Description
This book examines stealth liposomes from a multidisciplinary approach, which includes theoretical polymer physics, organic synthesis, colloid science, and biology. Discussions include theory, chemistry, biochemistry, pharmacology, preclinical studies in model systems, and medical applications in humans.

Gastrointestinal Physiology 2/E

Gastrointestinal Physiology 2/E PDF Author: Kim E. Barrett
Publisher: McGraw Hill Professional
ISBN: 0071774025
Category : Medical
Languages : en
Pages : 334

Book Description
Gain a complete understanding of the functioning of the gastrointestinal system with this concise, engagingly written text Gastrointestinal Physiology explains the operation and performance of one of the body's most crucial systems. Using clear, compelling language, the book's presentation makes it easy to absorb the content and integrate it as you learn the physiology of other bodily systems. Written to help you understand essential concepts rather than merely memorize facts, this unique text examines many medically relevant facets of this important body system, including anatomy, pathophysiology, and therapeutics, in concert with physiological information. FEATURES: Provides a thorough review of core concepts and highlights clinical application Covers the physiologic principles needed to understand and treat patients with digestive and liver diseases Includes clinical examples that link basic science with the practice of medicine Incorporates new information on emerging topics such as the communication between the intestine and central nervous system that controls food intake, the myriad roles newly ascribed to the intestinal microbiota, contemporary approaches to therapy for a number of GI maladies, and the role of the gut in obesity Enhanced by valuable learning aids such as study questions, learning objectives, key concepts, numerous illustrations and charts, and recommended readings

Oxford Handbook of Clinical Pharmacy

Oxford Handbook of Clinical Pharmacy PDF Author: Phil Wiffen
Publisher: Oxford University Press, USA
ISBN: 0199603642
Category : Medical
Languages : en
Pages : 696

Book Description
This handbook is the definitive quick reference guide to clinical pharmacy, providing practising and student pharmacists with a wealth of practical information.

Practical Manual of Experimental and Clinical Pharmacology

Practical Manual of Experimental and Clinical Pharmacology PDF Author: Bikash Mehdi
Publisher: Jaypee Brothers,Medical Publishers Pvt. Limited
ISBN: 9789386150721
Category : Medical
Languages : en
Pages : 430

Book Description


Endothelin Receptors

Endothelin Receptors PDF Author: Robert R. Ruffolo, Jr.
Publisher: CRC Press
ISBN: 9780849359385
Category : Science
Languages : en
Pages : 302

Book Description
Since the discovery of endothelin, major advances have been made in understanding the molecular structure and function of the endothelin receptors. At least two subtypes of receptors, designated ETA and ETB, have been identified through biochemical and pharmacological techniques. These subtypes are cloned and expressed and additional subtypes appear to exist. The biochemical events involved in the signal transduction processes that ultimately activate the cellular machinery involved in the end-organ responses are presented, as are the mechanisms by which the receptors recognize specific and different G-proteins. Functions mediated by the receptors at the cellular, tissue and, organ level are reviewed in detail, as well as the roles that they may play a part in the physiologic and pathophysiologic processes in animals and in humans. This book is unique in its breadth of scope. The most recent and important advances, from the intracellular level of the nucleus to the functional effect that endothelin receptors mediate in intact organs, are compiled and reviewed.