Remote C-H Bond Functionalizations PDF Download

Author: Debabrata Maiti
Publisher: John Wiley & Sons
ISBN: 3527346678
Category : Science
Languages : en
Pages : 450

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Book Description
A guide to contemporary advancements in the field of distal C-H functionalizations An important and dynamic topic within the modern field of organic synthesis, selective functionalization of C-H bonds can be used in a variety of applications across the pharmaceutical and agrochemical industries. Remote C-H Bond Functionalizations presents an inclusive account of the most recent developments and potential applications of performing variegated functionalizations selectively at the distal positions of organic compounds. Featuring contributions by an international team of experts, this authoritative volume provides deep insight into distal functionalizations, including detailed discussion of mechanisms, the engineering of templates, and the design of strategies. The text covers a diverse range of topics including C-H functionalization of palladium/norbornene catalysis, ruthenium-catalyzed remote functionalization, the non-directed distal C(sp2)-H, functionalization, transition metal catalyzed distal para-selective C-H functionalization, and much more. Reviewing contemporary advancements in the field while laying the foundation for future research, this important resource: Provides the most recent research and thorough coverage of the subject available in a single volume Offers practical information on C-H functionalizations in various industries Includes an up-to-date introduction to distal C-H functionalizations Remote C-H Bond Functionalizations is a must-read for every synthetic chemist, including chemists working with organometallics, organic chemists and researchers, and industrial chemists.

Author: LeGrande M. Slaughter
Publisher: Springer
ISBN: 3319137220
Category : Science
Languages : en
Pages : 292

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Book Description
The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students.

Author: Pietro Tundo
Publisher: Springer
ISBN: 3319300733
Category : Science
Languages : en
Pages : 614

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Book Description
Since the industrial revolution, chlorine remains an iconic molecule even though its production by the electrolysis of sodium chloride is extremely energy intensive. The rationale behind this book is to present useful and industrially relevant examples for alternatives to chlorine in synthesis. This multi-authored volume presents numerous contributions from an international spectrum of authors that demonstrate how to facilitate the development of industrially relevant and implementable breakthrough technologies. This volume will interest individuals working in organic synthesis in industry and academia who are working in Green Chemistry and Sustainable Technologies.

Author: A. C. Knipe
Publisher: John Wiley & Sons
ISBN: 1119125065
Category : Science
Languages : en
Pages : 717

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Book Description
Organic Reaction Mechanisms 2015, the 51st annual volume in this highly successful and unique series, surveys research on organic reaction mechanisms described in the available literature dated 2015. The following classes of organic reaction mechanisms are comprehensively reviewed: Reaction of Aldehydes and Ketones and their Derivatives Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives Oxidation and Reduction Carbenes and Nitrenes Nucleophilic Aromatic Substitution Electrophilic Aromatic Substitution Carbocations Nucleophilic Aliphatic Substitution Carbanions and Electrophilic Aliphatic Substitution Elimination Reactions Polar Addition Reactions Cycloaddition Reactions Molecular Rearrangements An experienced team of authors compile these reviews every year, so that the reader can rely on a continuing quality of selection and presentation.

Author: Michael Harmata
Publisher: John Wiley & Sons
ISBN: 1118057864
Category : Science
Languages : en
Pages : 395

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Book Description
The first authoritative book on using silver cations in organic chemistry—for catalysis and more! With more sophisticated catalytic methodologies fueling a resurgence in the study of cation-based chemistry, gold and platinum have stepped to the fore as the unique agents used to create new chemical reactions. Although these metals have become a primary focus of researchers in the field, another coinage metal that is often overlooked—but is as powerful as the others—is silver, a far less costly alternative to gold and platinum in aiding the development of new reactions. Making a strong case for the use of silver as a catalyst and structural element in organometal constructs, this authoritative book is the first to explore the benefits of using silver in organic chemistry by taking a close look at silver’s unique reactivity and structural characteristics for the development of new methods and materials. Silver in Organic Chemistry is: The first book to address catalysis using silver, whose use in organic chemistry is on the verge of exploding A resource for researchers wishing to do chemistry with silver cations, an area that stands in the shadow of gold chemistry, but still glistens, demonstrating that all that glitters is not gold—sometimes it’s silver! A guide for “first attempts” in working with silver cations Edited by a very well-respected, highly visible authority in this field Silver in Organic Chemistry promotes further scientific discussion by offering important new ways to examine the future possibilities of an emerging field. By elevating the importance of silver chemistry, this thought-provoking guide illustrates how this versatile metal can become an increasingly significant player in opening the door to new catalytic organic reactions and new organometal materials.

Author: Veronique Michelet
Publisher: World Scientific
ISBN: 1783265558
Category : Science
Languages : en
Pages : 564

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Book Description
Research on designing new catalytic systems has been one of the most important fields in modern organic chemistry. One reason for this is the predominant contribution of catalysis to the concepts of atom economy and green chemistry in the 21st century. Gold, considered catalytically inactive for a long time, is now a fascinating partner of modern chemistry, as scientists such as Bond, Teles, Haruta, Hutchings, Ito and Hayashi opened new perspectives for the whole synthetic chemist community. This book presents the major advances in homogeneous catalysis, emphasizing the methodologies that create carbon-carbon and carbon-heteroatom bonds, the applications that create diversity and synthesize natural products, and the recent advances and challenges in asymmetric catalysis and computational research.It provides readers with in-depth information about homogeneous gold-catalyzed reactions and presents several explanations for the scientific design of a catalyst. Readers will be able to understand the entire gold area and find solutions to problems in catalysis.Gold Catalysis — An Homogeneous Approach is part of the Catalytic Science Series and features prominent authors who are experts in their respective fields.

Author: Takahiko Akiyama
Publisher: John Wiley & Sons
ISBN: 1119736412
Category : Science
Languages : en
Pages : 798

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Book Description
Catalytic Asymmetric Synthesis Seminal text presenting detailed accounts of the most important catalytic asymmetric reactions known today This book covers the preparation of enantiomerically pure or enriched chemical compounds by use of chiral catalyst molecules. While reviewing the most important catalytic methods for asymmetric organic synthesis, this book highlights the most important and recent developments in catalytic asymmetric synthesis. Edited by two well-qualified experts, sample topics covered in the work include: Metal catalysis, organocatalysis, photoredox catalysis, enzyme catalysis C–H bond functionalization reactions Carbon–carbon bond formation reactions, carbon–halogen bond formation reactions, hydrogenations, polymerizations, flow reactions Axially chiral compounds Retaining the best of its predecessors but now thoroughly up to date with the important and recent developments in catalytic asymmetric synthesis, the 4th edition of Catalytic Asymmetric Synthesis serves as an excellent desktop reference and text for researchers and students, from upper-level undergraduates all the way to experienced professionals in industry or academia.

Author: Yasushi Nishihara
Publisher: Springer Science & Business Media
ISBN: 3642323685
Category : Science
Languages : en
Pages : 247

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Book Description
“Applied Cross-Coupling Reactions” provides students and teachers of advanced organic chemistry with an overview of the history, mechanisms and applications of cross-coupling reactions. Since the discovery of the transition-metal-catalyzed cross-coupling reactions in 1972, numerous synthetic uses and industrial applications have been developed. The mechanistic studies of the cross-coupling reactions have disclosed that three fundamental reactions: oxidative addition, transmetalation, and reductive elimination, are involved in a catalytic cycle. Cross-coupling reactions have allowed us to produce a variety of compounds for industrial purposes, such as natural products, pharmaceuticals, liquid crystals and conjugate polymers for use in electronic devices. Indeed, the Nobel Prize for Chemistry in 2010 was awarded for work on cross-coupling reactions. In this book, the recent trends in cross-coupling reactions are also introduced from the point of view of synthesis design and catalytic activities of transition-metal catalysts.

Author: Akkattu T. Biju
Publisher: John Wiley & Sons
ISBN: 3527346465
Category : Science
Languages : en
Pages : 530

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Book Description
A groundbreaking book to offer a a comprehensive account of important reactions involving arynes Modern Aryne Chemistry is the first book on the market to offer a conceptual framework to the reactions related to arynes. It also provides a systematic introduction to the cycloaddition reactions, insertion reactions and transition-metal-catalyzed transformations of arynes. The author, a noted expert on the topic, highlights a novel strategy for carbon-carbon and carbon-heteroatom bond construction using arynes. The book reveiws the recent use of aryne chemistry for the development of new multicomponent reactions. New advances in this area has shown rapid emergence of a new class of reactions classified under rearrangement reactions. The author also includes information on aryne methods that have been employed for the synthesis of several natural products. The simplicity and sophistication of the synthetic strategy using arynes can serve as a springboard for organic chemists to explore new possibilities and imagine applications of the concept of arynes. This important book: Presents a one-of-kind comprehensive guide to arynes reactions Offers a proven approach to the synthesis of natural product and polymers Reviews the most recent developments in the carbon-carbon and carbon-heteroatom bond-forming reactions involving arynes Written for organic, pharmaceutical, medicinal, natural products, and catalytic Chemists, Modern Aryne Chemistry offers a comprehensive review of the fundamentals of reactions related to arynes and the most recent developments in the field.

Author: Roberto Ballini
Publisher: John Wiley & Sons
ISBN: 3527347453
Category : Science
Languages : en
Pages : 322

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Book Description
Discover a comprehensive exploration of recent progress in the preparation of nitroalkanes from two leading voices in the field Nitroalkanes: Synthesis, Reactivity, and Applications delivers a thorough summary of the importance of nitroalkanes in organic synthesis. The book covers their preparation, transformation into other functional groups, like carbonyls and amines, and their use in the formation of single carbon-carbon or double carbon-carbon bonds. The distinguished authors have included chapters on acyclic and cyclic alpha-nitro ketones as well as the synthesis of cyclopropanes and spiro ketals. The book provides treatments of the application of nitroalkanes for the synthesis of important heterocycles, poly-functionalized structures, natural products, and compounds of biological and pharmaceutical interest. A one-stop resource in a topic that hasn???t been fully addressed by any other book in decades, this book covers the most important synthetic routes toward nitroalkanes. Readers will also benefit from the inclusion of: A thorough introduction to the synthesis of nitroalkanes, as well as the transformation of the nitro group into other functionalities An exploration of the formation of C-C single bonds, C=C double bonds, and the breaking of C3C bonds from cyclic alpha-nitro ketones Discussions of acyclic alpha-nitro ketones, nitroalkanes as precursors of cyclopropanes, and the synthesis of spiro ketals An examination of the preparation and synthetic applications of 1,3-Dinitroalkanes Perfect for organic chemists, natural products chemists, and catalytic chemists, Nitroalkanes: Synthesis, Reactivity, and Applications will also earn a place in the libraries of medicinal chemists seeking a one-stop resource for the most recent developments in the preparation of nitroalkanes, their functionalization, and their applications.