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Glyconanotechnology

Glyconanotechnology PDF Author: Tomáš Bertók
Publisher: CRC Press
ISBN: 0429827873
Category : Science
Languages : en
Pages : 342

Book Description
Glycomics (a comprehensive study of glycans, often denoted as the third alphabet of molecular biology, besides nucleic acids and proteins) relies on techniques that use "heavy machinery", such as mass spectrometry, liquid chromatography, and capillary electrophoresis. The use of biosensors and biochips for glycan analysis offers the possibility of lower costs, lower time and sample consumption, and ease of use. This highly interdisciplinary book introduces students, researchers, and professionals to the broad scope of this area, including the basics of nanotechnology and materials science, glycomics, and bioanalytical chemistry, as well as several historical facts, contexts and future perspectives. The introductory chapters are utilized in the book later for the state-of-the-art chapters on glycan-based diagnostics and imaging, enrichment techniques, and therapy, which makes this book unique and of great interest to a wide audience. The authors are skilled specialists and research scientists with many years of experience in this area and former investigators on a prestigious European Research Council Starting Grant.

Glyconanotechnology

Glyconanotechnology PDF Author: Tomáš Bertók
Publisher: CRC Press
ISBN: 0429827873
Category : Science
Languages : en
Pages : 342

Book Description
Glycomics (a comprehensive study of glycans, often denoted as the third alphabet of molecular biology, besides nucleic acids and proteins) relies on techniques that use "heavy machinery", such as mass spectrometry, liquid chromatography, and capillary electrophoresis. The use of biosensors and biochips for glycan analysis offers the possibility of lower costs, lower time and sample consumption, and ease of use. This highly interdisciplinary book introduces students, researchers, and professionals to the broad scope of this area, including the basics of nanotechnology and materials science, glycomics, and bioanalytical chemistry, as well as several historical facts, contexts and future perspectives. The introductory chapters are utilized in the book later for the state-of-the-art chapters on glycan-based diagnostics and imaging, enrichment techniques, and therapy, which makes this book unique and of great interest to a wide audience. The authors are skilled specialists and research scientists with many years of experience in this area and former investigators on a prestigious European Research Council Starting Grant.

Engineered Carbohydrate-Based Materials for Biomedical Applications

Engineered Carbohydrate-Based Materials for Biomedical Applications PDF Author: Ravin Narain
Publisher: John Wiley & Sons
ISBN: 1118002245
Category : Technology & Engineering
Languages : en
Pages : 416

Book Description
This book addresses the need for a comprehensive book on the design, synthesis, and characterization of synthetic carbohydrate-based polymeric materials along with their biological applications. The first two chapters cover the synthesis and self-assembly of glycopolymers and different techniques for creating these synthetic polymers. Subsequent chapters account for the preparation of block copolymers, branched glycopolymers, glycosurfaces, glycodendrimers, cationic glycopolymers, bioconjugates, glyconanoparticles and hydrogels. While these chapters comprehensively review the synthetic and characterization methods of those carbohydrate-based materials, their biological applications are discussed in detail.

Nanomaterials for Application in Medicine and Biology

Nanomaterials for Application in Medicine and Biology PDF Author: Michael Giersig
Publisher: Springer Science & Business Media
ISBN: 1402068298
Category : Technology & Engineering
Languages : en
Pages : 194

Book Description
This book unites the multi-faceted work of international scientists from various domains as they cooperate to present the role of nanomaterials in modern medicine with particular emphasis on cell growth, manipulation, and modification. Not only does this book provide the reader with the necessary theoretical background information, it also gives valuable experimental data, allowing for an exact comprehension and observation of the relevance of this modern technology.

Carbohydrates in Drug Design and Discovery

Carbohydrates in Drug Design and Discovery PDF Author: Jesus Jimenez-Barbero
Publisher: Royal Society of Chemistry
ISBN: 1849739994
Category : Science
Languages : en
Pages : 337

Book Description
In recent years there has been increasing evidence of the importance of carbohydrates and glycoconjugates in biomedical applications, and the use of synthetic ligands based on carbohydrates as drugs has received much attention. Focussing on drug discovery from key targets and placing an emphasis on the multi-disciplinary approaches necessary to challenge these issues, this book comprehensively covers the new and recent discoveries in the area of carbohydrate drug discovery. Carbohydrates in Drug Design and Discovery is split into five sections, beginning with a introduction and perspective on the current market. The book then goes on to discuss new synthetic methods in glycobiology, the use of glycobiology in chemical biology and glycobiology in drug discovery. Providing a worldwide perspective on this broad area, and providing examples of therapeutics already developed using these methods, this book provides a comprehensive introduction, discussion and update on this fast developing field for medicinal chemists and biochemists working in industry and academia.

Handbook of Carbohydrate-Modifying Biocatalysts

Handbook of Carbohydrate-Modifying Biocatalysts PDF Author: Peter Grunwald
Publisher: CRC Press
ISBN: 1351733982
Category : Medical
Languages : en
Pages : 1056

Book Description
This book provides an actual overview of the structure, function, and application of carbohydrate-modifying biocatalysts. Carbohydrates have been disregarded for a long time by the scientific community, mainly due to their complex structure. Meanwhile, the situation changed with increasing knowledge about the key role carbohydrates play in biological processes such as recognition, signal transduction, immune responses, and others. An outcome of research activities in glycoscience is the development of several new pharmaceuticals against serious diseases such as malaria, cancer, and various storage diseases. Furthermore, the employment of carbohydrate-modifying biocatalysts—enzymes as well as microorganisms—will contribute significantly to the development of environmentally friendly processes boosting a shift of the chemical industry from petroleum- to bio-based production of chemicals from renewable resources. The updated content of the second edition of this book has been extended by discussing the current state of the art of using recombinantly expressed carbohydrate-modifying biocatalysts and the synthesis of minicellulosomes in connection with consolidated bioprocessing of lignocellulosic material. Furthermore, a synthetic biology approach for using DAHP-dependent aldolases to catalyze asymmetric aldol reactions is presented.

Carbohydrate Nanotechnology

Carbohydrate Nanotechnology PDF Author: Keith J. Stine
Publisher: John Wiley & Sons
ISBN: 1118860241
Category : Science
Languages : en
Pages : 487

Book Description
Introducing the emerging field carbohydrate nanostructures, this book will be a unique resource for interested researchers to learn a range of methods of applying the field to their own work. Greater access, as well as greater collaboration, to this new interdisciplinary field is intended for both synthetic carbohydrate chemists and researchers in nanoscience related fields. It covers: the main types of nanostructures presently under investigation for modification by carbohydrates, including nanoparticles, nanorods, magnetic particles, dendrimers, nanoporous, and surface confined structures overview and introduction to the field of carbohydrate nanotechnology, and especially its applications to its biological systems Provides a unique resource for researchers to learn about the techniques used to characterize the physical and biological properties of carbohydrate-modified nanostructures

Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease

Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease PDF Author: Shyamasree Ghosh
Publisher: Academic Press
ISBN: 0128161272
Category : Science
Languages : en
Pages : 386

Book Description
Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesized post translationally, they play an important role in recognition, signaling, immunological response and cell-cell interaction. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era, sialoglybiology has become more and more important in deciphering health and disease conditions. - Discusses the sialic acids and their role in different diseases (other than cancer) - Provides an understanding of sialylations as post translational modifications (PTM) - Demonstrates the impact sialylation has on infectious diseases, the autoimmune system and health - Gives insights on the importance of sialic acid biology through animal models

Synthesis and Biological Applications of Glycoconjugates

Synthesis and Biological Applications of Glycoconjugates PDF Author: Olivier Renaudet
Publisher: Bentham Science Publishers
ISBN: 160805277X
Category : Science
Languages : en
Pages : 283

Book Description
The interactions between carbohydrates and proteins have been extensively explored in a wide range of physiological and pathological processes over several decades. The recent emergence of glycomics has strengthened this interest and notably contributed t

Advances in Carbohydrate Chemistry and Biochemistry

Advances in Carbohydrate Chemistry and Biochemistry PDF Author:
Publisher: Academic Press
ISBN: 0123808553
Category : Science
Languages : en
Pages : 562

Book Description
Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. - Features contributions from leading authorities and industry experts - Informs and updates on all the latest developments in the field

Advances in Nanotechnology Research and Application: 2012 Edition

Advances in Nanotechnology Research and Application: 2012 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 1464990468
Category : Technology & Engineering
Languages : en
Pages : 14172

Book Description
Advances in Nanotechnology Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Nanotechnology. The editors have built Advances in Nanotechnology Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nanotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Nanotechnology Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.