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Glial-Neuronal Communication in Development and Regeneration

Glial-Neuronal Communication in Development and Regeneration PDF Author: Hans H. Althaus
Publisher: Springer Science & Business Media
ISBN: 3642713815
Category : Medical
Languages : en
Pages : 807

Book Description
This comprehensive volume is a contribution to a new se ries initiated by the NATO Panel on "Gell to Gell Signals in Plants and Animals". The book reflects the outcome of an NATO work shop and bri ngs to mi nd two im portant questions: consideri ng the mass of relevant I iteratu reavai- able, is there any necessity for a new series of books - and considering the flood of compa rable meetings - is there any point in workshops of this nature and their publication? In order to deal with such questions adequately, much more space would be needed than is available in a foreword. Thus, the answers must remain rather superficial and, of course, rather subjective. To simplify the issue, the question of publication can be narrowed down to two fac tors - the financial risk, undertaken by the publisher, and the scientific risk, borne by the editor. If the book is good (with respect to lay-out and content) it will be a success - nothing will be lost the people involved will enhance their reputation! We are left with the question of the usefulness of workshops. Without doubt, it is indeed a useful procedure for experts to come together, in an atmosphere of harmony, and freedom from external pressures and time limitations, to discuss a well-defined theme. Wether in agreement or disagreement, a fair and open forum can be expectet for a variety of contributions.

Glial-Neuronal Communication in Development and Regeneration

Glial-Neuronal Communication in Development and Regeneration PDF Author: Hans H. Althaus
Publisher: Springer Science & Business Media
ISBN: 3642713815
Category : Medical
Languages : en
Pages : 807

Book Description
This comprehensive volume is a contribution to a new se ries initiated by the NATO Panel on "Gell to Gell Signals in Plants and Animals". The book reflects the outcome of an NATO work shop and bri ngs to mi nd two im portant questions: consideri ng the mass of relevant I iteratu reavai- able, is there any necessity for a new series of books - and considering the flood of compa rable meetings - is there any point in workshops of this nature and their publication? In order to deal with such questions adequately, much more space would be needed than is available in a foreword. Thus, the answers must remain rather superficial and, of course, rather subjective. To simplify the issue, the question of publication can be narrowed down to two fac tors - the financial risk, undertaken by the publisher, and the scientific risk, borne by the editor. If the book is good (with respect to lay-out and content) it will be a success - nothing will be lost the people involved will enhance their reputation! We are left with the question of the usefulness of workshops. Without doubt, it is indeed a useful procedure for experts to come together, in an atmosphere of harmony, and freedom from external pressures and time limitations, to discuss a well-defined theme. Wether in agreement or disagreement, a fair and open forum can be expectet for a variety of contributions.

Synaptic Function

Synaptic Function PDF Author: Neurosciences Institute (New York, N.Y.)
Publisher: Wiley-Interscience
ISBN:
Category : Medical
Languages : en
Pages : 808

Book Description
This book consists of five sections. The first section details methods for analyzing both presynaptic and postsynaptic function and emphasizes the molecular aspects of synapses. It describes ongoing studies of neurotransmitter release, voltage- sensitive ion channels, and electronic transmission at gap junctions. The second section focuses on the growing menagerie of neurotransmitters: their catagorization into chemical families, their relation to ion channels, their modulation by second messenger systems and their role in pharmacologic action. The third section considers the important relationship of transmitter diversity and synaptic types to the behavior of actual cellular networks. All of the studies described in these sections point to the necessity of considering interactions between anatomy, chemistry, physiology and pharmacology if synaptic function is to be understood at any one of these levels of analysis.

The Enteric Nervous System

The Enteric Nervous System PDF Author: John Barton Furness
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 312

Book Description


Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System

Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309212219
Category : Medical
Languages : en
Pages : 74

Book Description
Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.

Enteric Glia

Enteric Glia PDF Author: Brian D. Gulbransen
Publisher: Biota Publishing
ISBN: 1615046615
Category : Medical
Languages : en
Pages : 72

Book Description
The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography

Concepts of Biology

Concepts of Biology PDF Author: Samantha Fowler
Publisher:
ISBN: 9781739015503
Category :
Languages : en
Pages : 0

Book Description
Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.

Patterning and Cell Type Specification in the Developing CNS and PNS

Patterning and Cell Type Specification in the Developing CNS and PNS PDF Author:
Publisher: Academic Press
ISBN: 0123973481
Category : Science
Languages : en
Pages : 993

Book Description
The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. - Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop - Features leading experts in various subfields as Section Editors and article Authors - All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship - Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells

Brain Neurotrauma

Brain Neurotrauma PDF Author: Firas H. Kobeissy
Publisher: CRC Press
ISBN: 1466565993
Category : Medical
Languages : en
Pages : 718

Book Description
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Anatomy and Physiology

Anatomy and Physiology PDF Author: J. Gordon Betts
Publisher:
ISBN: 9781947172807
Category :
Languages : en
Pages : 0

Book Description


The Neuronal Environment

The Neuronal Environment PDF Author: Wolfgang Walz
Publisher: Springer Science & Business Media
ISBN: 1592591086
Category : Medical
Languages : en
Pages : 429

Book Description
Leading neuroscience researchers offer a fresh perspective on neuronal function by examining all its many components-including their pertubation during major disease states-and relate each element to neuronal demands. Topics range from the dependency of neurons on metabolic supply, as well as on both ion and transmitter homeostasis, to their close interaction with the myelin sheath. Also addressed are the astrocytic signaling system that controls synaptic transmission, the extracellular matrix and space as communication systems, the role of blood flow regulation in neuronal demand and in blood-brain barrier function, and inflammation and the neuroimmune system. Insightful and integrative, The Neuronal Environment: Brain Homeostasis in Health and Disease demonstrates a clear new understanding that neurons do not work in isolation, that they need constant interactions with other brain components to process information, and that they are not the only information processing system in the brain.