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Evaluating Human Genetic Diversity

Evaluating Human Genetic Diversity PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309184746
Category : Science
Languages : en
Pages : 101

Book Description
This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.

Evaluating Human Genetic Diversity

Evaluating Human Genetic Diversity PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309184746
Category : Science
Languages : en
Pages : 101

Book Description
This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.

Microbial Diversity in the Genomic Era

Microbial Diversity in the Genomic Era PDF Author: Surajit Das
Publisher: Academic Press
ISBN: 0128148500
Category : Science
Languages : en
Pages : 715

Book Description
Microbial Diversity in the Genomic Era presents insights on the techniques used for microbial taxonomy and phylogeny, along with their applications and respective pros and cons. Though many advanced techniques for the identification of any unknown bacterium are available in the genomics era, a far fewer number of the total microbial species have been discovered and identified to date. The assessment of microbial taxonomy and biosystematics techniques discovered and practiced in the current genomics era with suitable recommendations is the prime focus of this book. - Discusses the techniques used for microbial taxonomy and phylogeny with their applications and respective pros and cons - Reviews the evolving field of bacterial typing and the genomic technologies that enable comparative analysis of multiple genomes and the metagenomes of complex microbial environments - Provides a uniform, standard methodology for species designation

Plant Genome Diversity Volume 2

Plant Genome Diversity Volume 2 PDF Author: Johann Greilhuber
Publisher: Springer Science & Business Media
ISBN: 3709111609
Category : Science
Languages : en
Pages : 360

Book Description
This second of two volumes on Plant Genome Diversity provides, in 20 chapters, insights into the structural evolution of plant genomes with all its variations. Starting with an outline of plant phylogeny and its reconstruction, the second part of the volume describes the architecture and dynamics of the plant cell nucleus, the third examines the evolution and diversity of the karyotype in various lineages, including angiosperms, gymnosperms and monilophytes. The fourth part presents the mechanisms of polyploidization and its biological consequences and significance for land plant evolution. The fifth part deals with genome size evolution and its biological significance. Together with Volume I, this comprehensive book on the plant genome is intended for students and professionals in all fields of plant science, offering as it does a convenient entry into a burgeoning literature in a fast-moving field.

Genomic Diversity in People of India

Genomic Diversity in People of India PDF Author: Anthropological Survey Of India
Publisher: Springer Nature
ISBN: 9811601631
Category : Medical
Languages : en
Pages : 461

Book Description
This book is the output of Anthropological Survey of India's National Project "DNA Polymorphism of Contemporary Indian Population" conducted during 2000 to 2018. The book compiles the independent and collaborative work of 49 scientific personnel. Genomics facilitate the study of genetic constitution and diversity at individual and population levels. Genomic diversity explains susceptibility, predisposition and prolongation of diseases; personalized medicine and longevity; prehistoric demographic events, such as population bottleneck, expansion, admixture and natural selection. This book highlights the heterogeneous, genetically diverse population of India. It shows how the central geographic location of India, played a crucial role in historic and pre-historic human migrations, and in peopling different continents of the world. The book describes the massive task undertaken by AnSI to unearth genomic diversity of India populations, with the use of Uni-parental DNA markers mtDNA (mitochondrial DNA) and Y –chromosome in 75 communities. The book talks about the 61 maternal and 35 paternal lineages identified through these studies. It brings forth interesting, hitherto unknown findings such as shared mutations between certain communities. This volume is a milestone in scientific research to understand biological diversity of Indian people at genomic level. It addresses the basic priority to identify different genes underlying various inborn genetic defects and diseases specific to Indian populations. This would be highly interesting to population geneticists, historians, as well as anthropologists.

Oomycete Genetics and Genomics

Oomycete Genetics and Genomics PDF Author: Kurt Lamour
Publisher: John Wiley & Sons
ISBN: 0470475889
Category : Science
Languages : en
Pages : 602

Book Description
This book brings together the knowledge from and tools for genetic and genomic research into oomycetes to help solve the problems this pathogen poses to crops and animals. Armed with the information presented here, researchers can use oomycete data to solve practical problems and gain insight into future areas of interest. Key Features: Offers an up-to-date coverage of research into oomycetes – which has advanced with biochemical and molecular analyses in recent years Helps researchers use oomycete data to solve practical problems, like damage to crop and animal resources Includes a section on interactions with animal hosts Offers perspective on future areas of research Assembles an international author base

Genetic Diversity and Erosion in Plants

Genetic Diversity and Erosion in Plants PDF Author: M. R. Ahuja
Publisher: Springer
ISBN: 3319256378
Category : Science
Languages : en
Pages : 327

Book Description
Genetic erosion is the loss of genetic diversity within a species. It can happen very quickly, due to catastrophic events, or changes in land use leading to habitat loss. But it can also occur more gradually and remain unnoticed for a long time. One of the main causes of genetic erosion is the replacement of local varieties by modern varieties. Other causes include environmental degradation, urbanization, and land clearing through deforestation and brush fires. In order to conserve biodiversity in plants, it is important to targets three independent levels that include ecosystems, species and genes. Genetic diversity is important to a species’ fitness, long-term viability, and ability to adapt to changing environmental conditions. Chapters in this book are written by leading geneticists, molecular biologists and other specialists on relevant topics on genetic erosion and conservation genetic diversity in plants. This divisible set of two volumes deals with a broad spectrum of topics on genetic erosion, and approaches to biodiversity conservation in crop plants and trees. Volume 1 deals with indicators and prevention of genetic erosion, while volume 2 covers genetic diversity and erosion in a number of plants species. These two volumes will also be useful to botanists, biotechnologists, environmentalists, policy makers, conservationists, and NGOs working to manage genetic erosion and biodiversity.

The Pangenome

The Pangenome PDF Author: Hervé Tettelin
Publisher: Springer Nature
ISBN: 3030382818
Category : Science
Languages : en
Pages : 311

Book Description
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.

Genomic Diversity

Genomic Diversity PDF Author: Surinder Singh Papiha
Publisher: Springer Science & Business Media
ISBN: 1461542634
Category : Social Science
Languages : en
Pages : 268

Book Description
One of the major themes of human population genetics is assaying genetic variation in human populations. The ultimate goal of this objective is to understand the extent of genetic diversity and the use of this knowledge to reconstruct our evolutionary history. The discipline had undergone a revolutionary transition with the advent of molecular techniques in the 1980s. With this shift, statistical methods have also been developed to perceive the biological and molecular basis of human genetic variation. Using the new perspectives gained during the above transition, this volume describes the applications of molecular markers spanning the autosomal, Y-chromosomal and mitochondrial genome in the analysis of human diversity in contemporary populations. This is the first reference book of its kind to bring together data from these diverse sets of markers for understanding evolutionary histories and relationships of modern humans in a single volume.

Human Evolutionary Genetics

Human Evolutionary Genetics PDF Author: Mark Jobling
Publisher: Garland Science
ISBN: 1317952251
Category : Science
Languages : en
Pages : 1538

Book Description
Human Evolutionary Genetics is a groundbreaking text which for the first time brings together molecular genetics and genomics to the study of the origins and movements of human populations. Starting with an overview of molecular genomics for the non-specialist (which can be a useful review for those with a more genetic background), the book shows h

Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research

Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309488516
Category : Science
Languages : en
Pages : 123

Book Description
The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.