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Genome

Genome PDF Author: Matt Ridley
Publisher: Harper Collins
ISBN: 0062253468
Category : Science
Languages : en
Pages : 370

Book Description
“Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

Genome

Genome PDF Author: Matt Ridley
Publisher: Harper Collins
ISBN: 0062253468
Category : Science
Languages : en
Pages : 370

Book Description
“Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

Nature Via Nurture

Nature Via Nurture PDF Author: Matt Ridley
Publisher: Harper Collins
ISBN: 0060006781
Category : Psychology
Languages : en
Pages : 340

Book Description
Following his highly praised and bestselling book Genome: The Autobiography of a Species in 23 Chapters, Matt Ridley has written a brilliant and profound book about the roots of human behavior. Nature via Nurture explores the complex and endlessly intriguing question of what makes us who we are. In February 2001 it was announced that the human genome contains not 100,000 genes, as originally postulated, but only 30,000. This startling revision led some scientists to conclude that there are simply not enough human genes to account for all the different ways people behave: we must be made by nurture, not nature. Yet again biology was to be stretched on the Procrustean bed of the nature-nurture debate. Matt Ridley argues that the emerging truth is far more interesting than this myth. Nurture depends on genes, too, and genes need nurture. Genes not only predetermine the broad structure of the brain, they also absorb formative experiences, react to social cues, and even run memory. They are consequences as well as causes of the will. Published fifty years after the discovery of the double helix of DNA, Nature via Nurture chronicles a revolution in our understanding of genes. Ridley recounts the hundred years' war between the partisans of nature and nurture to explain how this paradoxical creature, the human being, can be simultaneously free-willed and motivated by instinct and culture. Nature via Nurture is an enthralling,up-to-the-minute account of how genes build brains to absorb experience.

Francis Crick

Francis Crick PDF Author: Matt Ridley
Publisher: Harper Collins
ISBN: 0062200666
Category : Biography & Autobiography
Languages : en
Pages : 228

Book Description
Francis Crick—the quiet genius who led a revolution in biology by discovering, quite literally, the secret of life—will be bracketed with Galileo, Darwin, and Einstein as one of the greatest scientists of all time. In his fascinating biography of the scientific pioneer who uncovered the genetic code—the digital cipher at the heart of heredity that distinguishes living from non-living things—acclaimed bestselling science writer Matt Ridley traces Crick's life from middle-class mediocrity in the English Midlands through a lackluster education and six years designing magnetic mines for the Royal Navy to his leap into biology at the age of thirty-one and its astonishing consequences. In the process, Ridley sheds a brilliant light on the man who forever changed our world and how we understand it.

The Red Queen

The Red Queen PDF Author: Matt Ridley
Publisher: Penguin UK
ISBN: 0141965452
Category : Psychology
Languages : en
Pages : 459

Book Description
Sex is as fascinating to scientists as it is to the rest of us. A vast pool of knowledge, therefore, has been gleaned from research into the nature of sex, from the contentious problem of why the wasteful reproductive process exists at all, to how individuals choose their mates and what traits they find attractive. This fascinating book explores those findings, and their implications for the sexual behaviour of our own species. It uses the Red Queen from ‘Alice in Wonderland’ – who has to run at full speed to stay where she is – as a metaphor for a whole range of sexual behaviours. The book was shortlisted for the 1994 Rhone-Poulenc Prize for Science Books. ‘Animals and plants evolved sex to fend off parasitic infection. Now look where it has got us. Men want BMWs, power and money in order to pair-bond with women who are blonde, youthful and narrow-waisted ... a brilliant examination of the scientific debates on the hows and whys of sex and evolution’ Independent.

The Human Genome

The Human Genome PDF Author: Julia E. Richards
Publisher: Academic Press
ISBN: 0080918654
Category : Science
Languages : en
Pages : 600

Book Description
Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, Third Edition will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Human Genome, Second Edition includes entirely new chapters on forensics, stem cell biology, bioinformatics, and societal/ethical issues associated with the field. New special features boxes make connections between human genetics and human health and disease. Carefully crafted pedagogy includes chapter-opening case studies that set the stage for each chapter; concept statements interspersed throughout the chapter that keep first-time students focused on key concepts; and end-of-chapter questions and critical thinking activities. This new edition will contribute to creating a genetically literate student population that understands basic biological research, understands elements of the personal and health implications of genetics, and participates effectively in public policy issues involving genetic information. - Includes topical material on forensics, disease studies, and the human genome project to engage non-specialist students - Full, 4-color illustration program enhances and reinforces key concepts and themes - Uniform organization of chapters includes interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers

The Gene

The Gene PDF Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
ISBN: 1476733538
Category : Medical
Languages : en
Pages : 624

Book Description
The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

Ancestors in Our Genome

Ancestors in Our Genome PDF Author: Eugene E. Harris (Professor)
Publisher:
ISBN: 0199978034
Category : Science
Languages : en
Pages : 249

Book Description
In 2001, scientists were finally able to determine the full human genome sequence, and with the discovery began a genomic voyage back in time. Since then, we have sequenced the full genomes of a number of mankind's primate relatives at a remarkable rate. The genomes of the common chimpanzee (2005) and bonobo (2012), orangutan (2011), gorilla (2012), and macaque monkey (2007) have already been identified, and the determination of other primate genomes is well underway. Researchers are beginning to unravel our full genomic history, comparing it with closely related species to answer age-old questions about how and when we evolved. For the first time, we are finding our own ancestors in our genome and are thereby gleaning new information about our evolutionary past. In Ancestors in Our Genome, molecular anthropologist Eugene E. Harris presents us with a complete and up-to-date account of the evolution of the human genome and our species. Written from the perspective of population genetics, and in simple terms, the book traces human origins back to their source among our earliest human ancestors, and explains many of the most intriguing questions that genome scientists are currently working to answer. For example, what does the high level of discordance among the gene trees of humans and the African great apes tell us about our respective separations from our common ancestor? Was our separation from the apes fast or slow, and when and why did it occur? Where, when, and how did our modern species evolve? How do we search across genomes to find the genomic underpinnings of our large and complex brains and language abilities? How can we find the genomic bases for life at high altitudes, for lactose tolerance, resistance to disease, and for our different skin pigmentations? How and when did we interbreed with Neandertals and the recently discovered ancient Denisovans of Asia? Harris draws upon extensive experience researching primate evolution in order to deliver a lively and thorough history of human evolution. Ancestors in Our Genome is the most complete discussion of our current understanding of the human genome available.

The Evolution of Everything

The Evolution of Everything PDF Author: Matt Ridley
Publisher: HarperCollins
ISBN: 0062296027
Category : Business & Economics
Languages : en
Pages : 279

Book Description
“Mr. Ridley’s best and most important work to date…there is something profoundly democratic and egalitarian—even anti-elitist—in this bottom-up approach: Everyone can have a role in bringing about change.” —Wall Street Journal The New York Times bestselling author of The Rational Optimist and Genome returns with a fascinating argument for evolution that definitively dispels a dangerous, widespread myth: that we can command and control our world Human society evolves. Change in technology, language, morality, and society is incremental, inexorable, gradual, and spontaneous. It follows a narrative, going from one stage to the next, and it largely happens by trial and error—a version of natural selection. Much of the human world is the result of human action but not of human design: it emerges from the interactions of millions, not from the plans of a few. Drawing on fascinating evidence from science, economics, history, politics, and philosophy, Matt Ridley demolishes conventional assumptions that the great events and trends of our day are dictated by those on high. On the contrary, our most important achievements develop from the bottom up. The Industrial Revolution, cell phones, the rise of Asia, and the Internet were never planned; they happened. Languages emerged and evolved by a form of natural selection, as did common law. Torture, racism, slavery, and pedophilia—all once widely regarded as acceptable—are now seen as immoral despite the decline of religion in recent decades. In this wide-ranging, erudite book, Ridley brilliantly makes the case for evolution, rather than design, as the force that has shaped much of our culture, our technology, our minds, and that even now is shaping our future.

The Tennis Partner

The Tennis Partner PDF Author: Abraham Verghese
Publisher: HarperCollins
ISBN: 0063389916
Category : Biography & Autobiography
Languages : en
Pages : 442

Book Description
An unforgettable, illuminating story of how men live and how they survive, from Abraham Verghese, the acclaimed New York Times bestselling author of Cutting for Stone and The Covenant of Water, an Oprah's Book Club Pick. “Heartbreaking. . . . Indelible and haunting, [The Tennis Partner] is an elegy to friendship found, and an ode to a good friend lost.”—The Boston Globe When Abraham Verghese, a physician whose marriage is unraveling, relocates to El Paso, Texas, he hopes to make a fresh start as a staff member at the county hospital. There he meets David Smith, a medical student recovering from drug addiction, and the two men begin a tennis ritual that allows them to shed their inhibitions and find security in the sport they love and with each other. This friendship between doctor and intern grows increasingly rich and complex, more intimate than two men usually allow. Just when it seems nothing can go wrong, the dark beast from David’s past emerges once again—and almost everything Verghese has come to trust and believe in is threatened as David spirals out of control.

The Human Genome Project

The Human Genome Project PDF Author: Thomas F. Lee
Publisher: Springer
ISBN: 1489960228
Category : Medical
Languages : en
Pages : 322

Book Description
Describes the ten-year, multimillion dollar Human Genome Project and its process of gene mapping; includes concerns of critics of the project.