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Author: Susana Nunes Silva Publisher: MDPI ISBN: 303650544X Category : Medical Languages : en Pages : 118
Book Description
Thyroid cancer is an uncommon type of cancer, but it is one of the most common endocrine malignancies. The etiology of thyroid cancer is multifactorial, and radiation is the best documented risk factor related to the disease. Further risk factors have been hypothesized; however, we have yet to gather a wide range of information that will help us better understand the genetic mechanisms of thyroid cancer. The influence of genetics in the clinic and in therapeutics has been improved based on retrospective and prospective studies published worldwide in the last few decades, but the development of high through-put approaches has also been crucial. The new advances in high through-put methodologies such as next generation sequencing will open the door to new genetic variants that will help to clarify genotype–phenotype correlations, new gene associations, new genetic targets useful as potential biomarkers, and so on. The new decade that is now beginning may provide new evidence for the disease. “Genetic Perspectives in Thyroid Cancer” is an issue that intends to cover several topics on thyroid cancer, aiming to reach new findings based on genetic evidence in thyroid cancer as expressed in case studies, molecular approaches, and hereditary evidences, clinical and therapeutic developments.
Author: Susana Nunes Silva Publisher: MDPI ISBN: 303650544X Category : Medical Languages : en Pages : 118
Book Description
Thyroid cancer is an uncommon type of cancer, but it is one of the most common endocrine malignancies. The etiology of thyroid cancer is multifactorial, and radiation is the best documented risk factor related to the disease. Further risk factors have been hypothesized; however, we have yet to gather a wide range of information that will help us better understand the genetic mechanisms of thyroid cancer. The influence of genetics in the clinic and in therapeutics has been improved based on retrospective and prospective studies published worldwide in the last few decades, but the development of high through-put approaches has also been crucial. The new advances in high through-put methodologies such as next generation sequencing will open the door to new genetic variants that will help to clarify genotype–phenotype correlations, new gene associations, new genetic targets useful as potential biomarkers, and so on. The new decade that is now beginning may provide new evidence for the disease. “Genetic Perspectives in Thyroid Cancer” is an issue that intends to cover several topics on thyroid cancer, aiming to reach new findings based on genetic evidence in thyroid cancer as expressed in case studies, molecular approaches, and hereditary evidences, clinical and therapeutic developments.
Author: T. Akamizu Publisher: Springer Science & Business Media ISBN: 4431678859 Category : Medical Languages : en Pages : 242
Book Description
The rapid developments in molecular genetics have clarified many of the muta tions in monogenic thyroid diseases over the last two decades; now the target of molecular thyroid genetics has become the oligogenic thyroid diseases. These include the autoimmune thyroid diseases and familial thyroid cancers, both of which are much commoner than the monogenic diseases. However, the method ological approach to the genetics of these more complex diseases is still far from being well established. Although the discovery of susceptibility genes has been partially accomplished in complex diseases such as asthma, Crohn's dis ease, and types I and II diabetes mellitus, the elucidation of susceptibility genes in complex diseases remains a major challenge. This volume contains papers presented at the International Symposium on the Genetics of Complex Thyroid Diseases. This meeting was held in association with the International Thyroid Congress in Kyoto in October 2000 and sup ported in part by the Japan Intractable Diseases Research Foundation and Knoll Pharmaceuticals Inc. The symposium was the first international symposium con cerning the genetics of complex thyroid diseases and was restricted to the study of the autoimmune thyroid diseases and familial thyroid cancer. Twenty distin guished researchers from the United States, the United Kingdom, France, Ger many, Italy, and Japan were invited. Each presentation precipitated intense dis cussion and there was much consensus during the meeting. Nevertheless, this volume will leave the reader with a clear understanding of how little we still know.
Author: Ifigenia Kostoglou-Athanassiou Publisher: Intechopen ISBN: 9781803562841 Category : Languages : en Pages : 0
Book Description
Thyroid cancer is the most common endocrine cancer, although it is relatively rare compared to other cancers. Standard treatment involves thyroidectomy and radioiodine administration followed by life-long thyroxine administration. However, until recently, there was no medical treatment for advanced thyroid cancer. Advances in the genetics of thyroid cancer and in the treatment of other forms of cancer with tyrosine kinase inhibitors have revolutionized the treatment of advanced thyroid cancer. This book provides a comprehensive overview of thyroid cancer. It is organized into two sections on genetics and treatment. Chapters address such topics as the genetic susceptibility to differentiated thyroid cancer, the molecular basis of radioiodine treatment in thyroid cancer, recent developments in the medical treatment of advanced thyroid cancer, systemic therapy in thyroid cancer, and much more.
Author: Paolo Vitti Publisher: Springer ISBN: 9783319450124 Category : Medical Languages : en Pages : 770
Book Description
This book presents the latest advances in knowledge of the pathogenesis of thyroid diseases and describes the state of the art in their diagnosis and treatment, including newly emerging management approaches. After an opening section that addresses thyroid physiology and laboratory evaluation, each of the major thyroid diseases and their subtypes is discussed, covering goiter and thyroid nodule, thyroiditis, hypothyroidism, hyperthyroidism and thyrotoxicosis, and thyroid carcinoma. Other conditions that affect thyroid function or induce thyroid dysfunction are also considered, e.g., pregnancy, non-thyroidal disorders, and medication use. The book is designed to assist practitioners to achieve optimal outcomes in clinical routine by providing clear guidance on clinical examination, the use of diagnostic tests, first- and second-line therapies, and follow-up. Chapter have been written by recognized experts in the field.
Author: Douglas P. Clark Publisher: Springer Science & Business Media ISBN: 1441959548 Category : Medical Languages : en Pages : 206
Book Description
Eighth volume to be published in the Essentials in Cytopathology book series. More than 115 full-color images, 12 tables and a series of algorithms. Designed to be concise and easy to use. Fits in lab coat pocket. Site specific. Illustration oriented accompanied by text in outline format. A must-have for every pathologist, cytopathologist, cytotechnologist, fellow and trainee.
Author: John A.H. Wass Publisher: Oxford University Press, USA ISBN: 0199235295 Category : Medical Languages : en Pages : 2158
Book Description
Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.
Author: Karel Pacak Publisher: John Wiley & Sons ISBN: 0470766387 Category : Medical Languages : en Pages : 184
Book Description
Pheochromocytomas are rare but treacherous catecholamine-producing tumors, which if missed or not properly treated, will almost invariably prove fatal. Prompt diagnosis is, therefore, essential for effective treatment, usually by surgical resection. The manifestations are diverse and the tumor can mimic a variety of conditions, often resulting in either erroneous diagnoses or a delayed diagnosis. Reflecting the recent leaps in understanding this condition, Pheochromocytoma: Diagnosis, Localization, and Treatment provides a comprehensive update on the improvements in the diagnosis, localization, management and treatment of pheochromocytomas – providing you with the latest cutting edge science alongside best clinical practice. Written by the leading names in the field, the text details the significant developments in understanding the genetics and biology of the tumors, coupled with technological advances in the fields of analytical chemistry, genomics, molecular biology and nuclear medicine. The most comprehensive book on pheochromocytoma Provides cutting edge science and clinical guidance Written by the leading names in the field Authors present their recently developed novel biochemical test for the diagnosis of Pheochromocytoma
Author: NADIR R. FARID Publisher: Springer Science & Business Media ISBN: 1402081073 Category : Medical Languages : en Pages : 441
Book Description
- This series is indexed in index Medicus - The turn around time for this series is fast, making the research as accurate as a journal
Author: Susana Nunes Silva
Author: Susana Nunes Silva
Author: Vasyl Vasko
Author: T. Akamizu
Author: Ujjal K. Mallick
Author: Ifigenia Kostoglou-Athanassiou
Author: Paolo Vitti
Author: Douglas P. Clark
Author: John A.H. Wass
Author: Karel Pacak
Author: NADIR R. FARID