Author: Alpo Juhani Vuorio
Publisher: Frontiers Media SA
ISBN: 2889669734
Category : Science
Languages : en
Pages : 190
Book Description
Genetics of Familial Hypercholesterolemia: New Insight
High Density Lipoproteins
Author: Arnold von Eckardstein
Publisher: Springer
ISBN: 9783319096643
Category : Medical
Languages : en
Pages : 0
Book Description
In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation. The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.
Publisher: Springer
ISBN: 9783319096643
Category : Medical
Languages : en
Pages : 0
Book Description
In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation. The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.
Genetic Determinants of Human Longevity
Author: Giuseppina Rose
Publisher: MDPI
ISBN: 3039216783
Category : Science
Languages : en
Pages : 118
Book Description
In the last two decades, due to the continuous increase of lifespans in Western societies, and the consequent growing of the elderly population, have witnessed an increase in the number of studies on biological and molecular factors able to promote healthy aging and reach longevity. The study of the genetic component of human longevity demonstrated that it accounts for 25% of intra population phenotype variance. The efforts made to characterize the genetic determinants suggested that the maintenance of cellular integrity, inflammation, oxidative stress response, DNA repair, as well as the use of nutrients, represent the most important pathways correlated with a longer lifespan. However, although a plethora of variants were indicated to be associated with human longevity, only very few were successfully replicated in different populations, probably because of population specificity, missing heritability as well as a complex interaction among genetic factors with lifestyle and cultural factors, which modulate the individual chance of living longer. Thus, many challenges remain to be addressed in the search for the genetic components of human longevity. This Special Issue is aimed to unify the progress in the analysis of the genetic determinants of human longevity, to take stock of the situation and point to future directions of the field. We invite submissions for reviews, research articles, short-communications dealing with genetic association studies in human longevity, including all types of genetic variation, as well as the characterization of longevity-related genes.
Publisher: MDPI
ISBN: 3039216783
Category : Science
Languages : en
Pages : 118
Book Description
In the last two decades, due to the continuous increase of lifespans in Western societies, and the consequent growing of the elderly population, have witnessed an increase in the number of studies on biological and molecular factors able to promote healthy aging and reach longevity. The study of the genetic component of human longevity demonstrated that it accounts for 25% of intra population phenotype variance. The efforts made to characterize the genetic determinants suggested that the maintenance of cellular integrity, inflammation, oxidative stress response, DNA repair, as well as the use of nutrients, represent the most important pathways correlated with a longer lifespan. However, although a plethora of variants were indicated to be associated with human longevity, only very few were successfully replicated in different populations, probably because of population specificity, missing heritability as well as a complex interaction among genetic factors with lifestyle and cultural factors, which modulate the individual chance of living longer. Thus, many challenges remain to be addressed in the search for the genetic components of human longevity. This Special Issue is aimed to unify the progress in the analysis of the genetic determinants of human longevity, to take stock of the situation and point to future directions of the field. We invite submissions for reviews, research articles, short-communications dealing with genetic association studies in human longevity, including all types of genetic variation, as well as the characterization of longevity-related genes.
Structure and Function of Apolipoproteins
Author: Maryvonne Rosseneu
Publisher: CRC Press
ISBN: 9780849369063
Category : Medical
Languages : en
Pages : 456
Book Description
Structure and Function of Apolipoproteins presents a comprehensive review of the primary and secondary structure of apolipoproteins. The book discusses the structure of the apolipoprotein gene family and genetic variation occurring at the protein level. Functional properties of apolipoproteins, including lipid binding, enzyme co-factor activity, antigenic properties, and receptor-ligand interactions are extensively described and analyzed in relation to their structural features. Physiological properties of apolipoproteins and their role in biology and medicine are also examined. Anyone who is interested in apolipoproteins or is conducting research on atherosclerosis should consider this volume an essential reference.
Publisher: CRC Press
ISBN: 9780849369063
Category : Medical
Languages : en
Pages : 456
Book Description
Structure and Function of Apolipoproteins presents a comprehensive review of the primary and secondary structure of apolipoproteins. The book discusses the structure of the apolipoprotein gene family and genetic variation occurring at the protein level. Functional properties of apolipoproteins, including lipid binding, enzyme co-factor activity, antigenic properties, and receptor-ligand interactions are extensively described and analyzed in relation to their structural features. Physiological properties of apolipoproteins and their role in biology and medicine are also examined. Anyone who is interested in apolipoproteins or is conducting research on atherosclerosis should consider this volume an essential reference.
Coronaries and Cholesterol
Author: Walter John Cliff
Publisher:
ISBN:
Category : Cholesterol
Languages : en
Pages : 264
Book Description
Publisher:
ISBN:
Category : Cholesterol
Languages : en
Pages : 264
Book Description
Clinical and genetic determinants of diabetes and complications
Author: Sen Li
Publisher: Frontiers Media SA
ISBN: 2832542573
Category : Medical
Languages : en
Pages : 336
Book Description
Publisher: Frontiers Media SA
ISBN: 2832542573
Category : Medical
Languages : en
Pages : 336
Book Description
Report by the Task Force on Genetic Factors in Atherosclerotic Diseases
Author: National Heart and Lung Institute. Division of Heart and Vascular Diseases
Publisher:
ISBN:
Category : Arteriosclerosis
Languages : en
Pages : 264
Book Description
Publisher:
ISBN:
Category : Arteriosclerosis
Languages : en
Pages : 264
Book Description
Coronary Primary Prevention Trial
Author:
Publisher:
ISBN:
Category : Coronary heart disease
Languages : en
Pages : 2
Book Description
Publisher:
ISBN:
Category : Coronary heart disease
Languages : en
Pages : 2
Book Description
Statin-Associated Muscle Symptoms
Author: Paul D. Thompson
Publisher: Springer Nature
ISBN: 3030333043
Category : Medical
Languages : en
Pages : 191
Book Description
This book provides an overview of statin-associated muscle symptoms (SAMS) from clinical presentation to treatment and possible metabolic causes. It examines the risk factors, presentations, diagnosis and differential diagnosis, clinical management, and financial costs of SAMS. The book also highlights patients’ perspectives on SAMS such as the psychosocial, emotional, and societal factors influencing their perceptions and experiences. Finally, the book presents the results of observational and clinical trials on the prevalence of SAMS, clinical trials for treatments, and potential future research approaches for improving the understanding and treatment of SAMS. A key addition to the Contemporary Cardiology series, Statin-Associated Muscle Symptoms is an essential resource for physicians, medical students, residents, fellows, and allied health professionals in cardiology, endocrinology, pharmacotherapy, primary care, and health promotion and disease prevention.
Publisher: Springer Nature
ISBN: 3030333043
Category : Medical
Languages : en
Pages : 191
Book Description
This book provides an overview of statin-associated muscle symptoms (SAMS) from clinical presentation to treatment and possible metabolic causes. It examines the risk factors, presentations, diagnosis and differential diagnosis, clinical management, and financial costs of SAMS. The book also highlights patients’ perspectives on SAMS such as the psychosocial, emotional, and societal factors influencing their perceptions and experiences. Finally, the book presents the results of observational and clinical trials on the prevalence of SAMS, clinical trials for treatments, and potential future research approaches for improving the understanding and treatment of SAMS. A key addition to the Contemporary Cardiology series, Statin-Associated Muscle Symptoms is an essential resource for physicians, medical students, residents, fellows, and allied health professionals in cardiology, endocrinology, pharmacotherapy, primary care, and health promotion and disease prevention.
Weight Management
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309089964
Category : Medical
Languages : en
Pages : 277
Book Description
The primary purpose of fitness and body composition standards in the U.S. Armed Forces has always been to select individuals best suited to the physical demands of military service, based on the assumption that proper body weight and composition supports good health, physical fitness, and appropriate military appearance. The current epidemic of overweight and obesity in the United States affects the military services. The pool of available recruits is reduced because of failure to meet body composition standards for entry into the services and a high percentage of individuals exceeding military weight-for-height standards at the time of entry into the service leave the military before completing their term of enlistment. To aid in developing strategies for prevention and remediation of overweight in military personnel, the U.S. Army Medical Research and Materiel Command requested the Committee on Military Nutrition Research to review the scientific evidence for: factors that influence body weight, optimal components of a weight loss and weight maintenance program, and the role of gender, age, and ethnicity in weight management.
Publisher: National Academies Press
ISBN: 0309089964
Category : Medical
Languages : en
Pages : 277
Book Description
The primary purpose of fitness and body composition standards in the U.S. Armed Forces has always been to select individuals best suited to the physical demands of military service, based on the assumption that proper body weight and composition supports good health, physical fitness, and appropriate military appearance. The current epidemic of overweight and obesity in the United States affects the military services. The pool of available recruits is reduced because of failure to meet body composition standards for entry into the services and a high percentage of individuals exceeding military weight-for-height standards at the time of entry into the service leave the military before completing their term of enlistment. To aid in developing strategies for prevention and remediation of overweight in military personnel, the U.S. Army Medical Research and Materiel Command requested the Committee on Military Nutrition Research to review the scientific evidence for: factors that influence body weight, optimal components of a weight loss and weight maintenance program, and the role of gender, age, and ethnicity in weight management.