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Environmental Epigenetics

Environmental Epigenetics PDF Author: L. Joseph Su
Publisher: Springer
ISBN: 1447166787
Category : Medical
Languages : en
Pages : 327

Book Description
This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Environmental Epigenetics

Environmental Epigenetics PDF Author: L. Joseph Su
Publisher: Springer
ISBN: 1447166787
Category : Medical
Languages : en
Pages : 327

Book Description
This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Genetic Control of Environmental Pollutants

Genetic Control of Environmental Pollutants PDF Author: Gilbert S. Omenn
Publisher: Springer Science & Business Media
ISBN: 1468447157
Category : Nature
Languages : en
Pages : 405

Book Description
Gilbert S. Omenn Dean, Public Health and Community Medicine University of Washington Seattle, Washington 98195 On behalf of the University of Washington, the City of Seattle, the sponsors and donors, and my co-organizers, I am delighted to welcome all of you to this Conference on Genetic Control of Environ mental Pollutants. My only regret is that Dr. Alexander Hollaender, who has inspired so many of us as young scientists and stimulated so many trail-blazing conferences in environmental sciences and in gen etic engineering, is ill and was unable to make the trip to Seattle. He sends his warm good wishes for an outstanding meeting and a fine volume. The purpose of this Conference is to identify and assess strat egies for more effectively and safely managing wastes and toxic sub stances in the environment, in part through use of genetically engi neered microorganisms. There is a sense of desperation in our soci ety that modern technologies have introduced a bewildering array of potential hazards to human health and to our environment. There is an accompanying sense of frustration that our prodigious basic re search capabilities and our technological ingenuity have not yielded practical ways to control many pollutants and waste streams, or- better still--to convert them to useful products.

U.S. Health in International Perspective

U.S. Health in International Perspective PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309264146
Category : Social Science
Languages : en
Pages : 421

Book Description
The United States is among the wealthiest nations in the world, but it is far from the healthiest. Although life expectancy and survival rates in the United States have improved dramatically over the past century, Americans live shorter lives and experience more injuries and illnesses than people in other high-income countries. The U.S. health disadvantage cannot be attributed solely to the adverse health status of racial or ethnic minorities or poor people: even highly advantaged Americans are in worse health than their counterparts in other, "peer" countries. In light of the new and growing evidence about the U.S. health disadvantage, the National Institutes of Health asked the National Research Council (NRC) and the Institute of Medicine (IOM) to convene a panel of experts to study the issue. The Panel on Understanding Cross-National Health Differences Among High-Income Countries examined whether the U.S. health disadvantage exists across the life span, considered potential explanations, and assessed the larger implications of the findings. U.S. Health in International Perspective presents detailed evidence on the issue, explores the possible explanations for the shorter and less healthy lives of Americans than those of people in comparable countries, and recommends actions by both government and nongovernment agencies and organizations to address the U.S. health disadvantage.

Gene Drives on the Horizon

Gene Drives on the Horizon PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309437873
Category : Science
Languages : en
Pages : 231

Book Description
Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.

Finding a Path to Safety in Food Allergy

Finding a Path to Safety in Food Allergy PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309450314
Category : Medical
Languages : en
Pages : 575

Book Description
Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.

Genetic Issues in Public Health and Medicine

Genetic Issues in Public Health and Medicine PDF Author: Bernice H. Cohen
Publisher: Charles C. Thomas Publisher
ISBN:
Category : Medical
Languages : en
Pages : 520

Book Description
The many advantages in human genetics and their contingent problems and implications make it increasingly necessary to understand the converging relationships with other fields. The interaction between genetics and medicine, medicine and the community, and genetics and the community, are obvious. However, the point where the three sets of concerns intersect comprises issues of social, political, legal, economic, and moral-ethical impact. Some issues are simply tangential, but others that are more controversial reach to the philosophical core of scientific inquiry itself. That intersection of issues prompted this collection, which was sparked by a series of seminars. So that present and future decision makers can deal effectively with these growing reciprocal concerns and their consequences-real and potential they need an overview of the significant genetic issues in public health. Our approach has been to focus mainly on the applications of genetic knowledge and on its various concomitant problems. In addition to general remarks in the Foreword and comments preceding each section, transitional introductions precede chapters where necessary.

Epigenetic Epidemiology

Epigenetic Epidemiology PDF Author: Karin B. Michels
Publisher: Springer Science & Business Media
ISBN: 9400724950
Category : Medical
Languages : en
Pages : 450

Book Description
The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored.This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!

Bioremediation of Pollutants

Bioremediation of Pollutants PDF Author: Vijai Singh
Publisher: Elsevier
ISBN: 0128190264
Category : Science
Languages : en
Pages : 490

Book Description
Bioremediation of Pollutants: From Genetic Engineering to Genome Engineering provides insights into genetic and genome engineering strategies in bioremediation, covering a wide range of microorganisms that are key to the removal of pollutants. The book includes discussions on root engineering, transgenic plants, metagenomics, bioreactors, molecular biology tools, genome editing, synthetic biology, microbial indicators, biosurfactants, biofilms, genetically modified organisms, and engineered fungi and bacteria. Presented by top experts in the field, this resource captures the essence and diversity of bioremediation methodologies in a single source. Students and beginners in environmental science, researchers, soil scientists, genetic and genome engineers, stakeholders and policymakers interested in improving this rapidly growing area of research will find this resource extremely useful. - Draws together research from eminent scientists from across the globe in the areas of phytoremediation and microbial remediation - Includes case studies of engineered bacterial remediation - Covers the genome editing CRISPR-Cas9 system that has been less explored in plants and microorganisms

Ecological and Genetic Implications of Aquaculture Activities

Ecological and Genetic Implications of Aquaculture Activities PDF Author: Theresa M. Bert
Publisher: Springer Science & Business Media
ISBN: 140206148X
Category : Technology & Engineering
Languages : en
Pages : 537

Book Description
In this book, numerous prominent aquaculture researchers contribute 27 chapters that provide overviews of aquaculture effects on the environment. They comprise a comprehensive synthesis of many ecological and genetic problems implicated in the practice of aquaculture and of many proven, attempted, or postulated solutions to those problems. This is an outstanding source of reference for all types of aquaculture activities.

Phytoremediation of Contaminated Soil and Water

Phytoremediation of Contaminated Soil and Water PDF Author: Norman Terry
Publisher: CRC Press
ISBN: 9781439822654
Category : Science
Languages : en
Pages : 414

Book Description
Phytoremediation is an exciting, new technology that utilizes metal-accumulating plants to rid soil of heavy metal and radionuclides. Hyperaccumulation plants are an appealing and economical alternative to current methods of soil recovery. Phytoremediation of Contaminated Soil and Water is the most thorough literary examination of the subject available today. The successful implementation of phytoremediation depends on identifying plant material that is well adapted to specific toxic sites. Gentle remediation is then applied in situ, or at the contamination site. No soil excavation or transport is necessary. This severely contains the potential risk of the pollutants entering the food chain. And it's cost effective. The progress of modern man has created many sites contaminated with heavy metals. The effected land is toxic to plants and animals , which creates considerable public interest in remediation. But the commonly used remedies are ex situ, which poses an expensive dilemma and an even greater threat. Phytoremediation offers the prospect of a cheaper and healthier way to deal with this problem. Read Phytoremediation of Contaminated Soil and Water to learn just how far this burgeoning technology has developed.