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Homeostasis

Homeostasis PDF Author: Fernanda Lasakosvitsch Castanho
Publisher: BoD – Books on Demand
ISBN: 1789850770
Category : Medical
Languages : en
Pages : 174

Book Description
The human body is composed of several systems and organs, consisting of millions of cells that need relatively stable conditions to function and contribute to the survival of the body as a whole. The maintenance of stable conditions for the cells against the variations of the external environment is an essential function of the body and is called homeostasis. As a consequence of the loss of homeostasis, a disease is manifested. This book aims to provide the reader with an up-to-date view of the self-regulatory mechanisms that are activated to achieve homeostasis, the pathways that are altered during the disease process, and how medicine can intervene to restore balance in critical patients.

Homeostasis

Homeostasis PDF Author: Fernanda Lasakosvitsch Castanho
Publisher: BoD – Books on Demand
ISBN: 1789850770
Category : Medical
Languages : en
Pages : 174

Book Description
The human body is composed of several systems and organs, consisting of millions of cells that need relatively stable conditions to function and contribute to the survival of the body as a whole. The maintenance of stable conditions for the cells against the variations of the external environment is an essential function of the body and is called homeostasis. As a consequence of the loss of homeostasis, a disease is manifested. This book aims to provide the reader with an up-to-date view of the self-regulatory mechanisms that are activated to achieve homeostasis, the pathways that are altered during the disease process, and how medicine can intervene to restore balance in critical patients.

Bioelectronic Medicine

Bioelectronic Medicine PDF Author: Valentin A. Pavlov
Publisher: Perspectives Cshl
ISBN: 9781621823025
Category : Medical
Languages : en
Pages : 350

Book Description
"Cold Spring Harbor perspectives in medicine."

Nutrition and Lifestyle in Neurological Autoimmune Diseases

Nutrition and Lifestyle in Neurological Autoimmune Diseases PDF Author: Ronald Ross Watson
Publisher: Academic Press
ISBN: 0128054441
Category : Health & Fitness
Languages : en
Pages : 304

Book Description
Nutrition and Lifestyle in Neurological Autoimmune Diseases: Multiple Sclerosis discusses important discoveries relating to the types of, and efficacy of, nutritional and lifestyle responses to symptoms and reoccurrence of MS. Each chapter defines a new approach to use in foods, dietary supplements, exercise, behavior, and/or lifestyle in health promotion and symptoms management for MS. This book presents the role of non-pharmaceutical approaches and is essential reading for neurologists, physicians, nurses, nutritionists, dietitians, healthcare professionals, research scientists, biochemists, and general practitioners. - Presents a comprehensive overview that details the role of nutrition and exercise in Multiple Sclerosis - Written for researchers and clinicians in neurology, neuroscience, and exercise and nutrition - Defines a new approach that focuses on foods, dietary supplements, exercise, behavior, and lifestyle in health promotion and symptoms management for MS

Multiple Sclerosis

Multiple Sclerosis PDF Author: Alireza Minagar
Publisher: Academic Press
ISBN: 0128010053
Category : Science
Languages : en
Pages : 540

Book Description
Multiple Sclerosis: A Mechanistic View provides a unique view of the pathophysiology of multiple sclerosis (MS) and related disorders. As the only book on the market to focus on the mechanisms of MS rather than focusing on the clinical features and treatment of the disease, it describes the role of genetic and environmental factors in the pathogenesis of MS, the role of specific cells in the pathophysiology of the disease, and the pathophysiology of inflammatory and neurodegenerative disorders related to MS. The book provides discussion of neurodegeneration and neuroregeneration, two critical emerging areas of research, as well as detailed discussion of the mechanisms of action of the approved and investigational drugs for treatment of MS and the emerging role of magnetic resonance spectroscopy (MRI) in investigations into MS. It is the only book on the market to offer comprehensive coverage of the known mechanisms of MS and related diseases, and contains contributions from physicians and researchers who are worldwide experts in the field of study. - Focuses on the pathophysiologic mechanisms of multiple sclerosis and the mechanisms of action in agents for the treatment of MS - Discusses the roles of neurodegeneration and neuroregeneration in MS and related diseases - Authored and edited by international leaders in the field of MS research

Neuro-Immune Interactions in Inflammation and Autoimmunity

Neuro-Immune Interactions in Inflammation and Autoimmunity PDF Author: Valentin A. Pavlov
Publisher: Frontiers Media SA
ISBN: 2889455335
Category :
Languages : en
Pages : 222

Book Description
The nervous system plays an important role in the regulation of immunity and inflammation. On the other hand unbalanced immune responses in inflammatory and autoimmune conditions may have a deleterious impact on neuronal integrity and brain function. Recent studies have characterized neural pathways communicating peripheral inflammatory signals to the CNS, and brain- and spinal cord-derived circuitries controlling various innate and adaptive immune responses and inflammation. A prototypical neural reflex circuit that regulates immunity and inflammation is the vagus nerve-based “inflammatory reflex”. Ongoing research has revealed cellular and molecular mechanisms underlying these neural circuits and indicated new therapeutic approaches in inflammatory and autoimmune disorders. Pharmacological and bioelectronic modulation of neural circuitry has been successfully explored in preclinical settings of sepsis, arthritis, inflammatory bowel disease, obesity-driven disorders, diabetes and other diseases. These studies paved the way to successful clinical trials with bioelectronic neuronal modulation in rheumatoid arthritis and inflammatory bowel disease. Dysregulated release of cytokines and other inflammatory molecules may have a severe impact on brain function. Brain inflammation (neuroinflammation), imbalances in brain neuronal integrity and neurotransmitter systems, and cognitive impairment are characteristic features of post-operative conditions, sepsis, liver diseases, diabetes and other disorders characterized by immune and metabolic dysregulation. Derangements in cytokine release also play a pivotal role in depression. Characteristic brain reactive antibodies in autoimmune conditions, including systemic lupus erythematosus and neuromyelitis optica, significantly contribute to brain pathology and cognitive impairment. These studies, and the simultaneous characterization of neuro-protective cytokines, identified new therapeutic approaches for treating neurological complications in inflammatory and autoimmune disorders. This Frontiers Research Topic is a forum for publishing research findings and methodological and conceptual advances at the intersection of immunology and neuroscience. We hope that presenting new insight into bi-directional neuro-immune communication in inflammation and autoimmunity will foster further collaborations and facilitate the development of new efficient therapeutic strategies.

Understanding Pain

Understanding Pain PDF Author: Fernando Cervero
Publisher: MIT Press
ISBN: 0262304503
Category : Health & Fitness
Languages : en
Pages : 189

Book Description
An expert explores the biological and emotional nature of pain: why it hurts and why some pain is good and some pain is bad. If you touch something hot, it hurts. You snatch your hand away from the hot thing immediately. Obviously. But what is really happening, biologically—and emotionally? In Understanding Pain, Fernando Cervero explores the mechanisms and the meaning of pain. When you touch something hot, your brain triggers a reflex action that causes you to withdraw your hand, protecting you from injury. That kind of pain, Cervero explains, is actually good for us; it acts as an alarm that warns us of danger and keeps us away from harm. But, Cervero tells us, not all pain is good for you. There is another kind of pain that is more like a curse: chronic pain that is not related to injury. This is the kind of pain that fills pain clinics and makes life miserable. Cervero describes current research into the mysteries of chronic pain and efforts to develop more effective treatments. Cervero reminds us that pain is the most common reason for people to seek medical attention, but that it remains a biological enigma. It is protective, but not always. Its effects are not only sensory but also emotional. There is no way to measure it objectively, no test that comes back positive for pain; the only way a medical professional can gauge pain is by listening to the patient's description of it. The idea of pain as a test of character or a punishment to be borne is changing; prevention and treatment of pain are increasingly important to researchers, clinicians, and patients. Cervero's account brings us closer to understanding the meaning of pain.

Psychosomatic

Psychosomatic PDF Author: Elizabeth A. Wilson
Publisher: Duke University Press
ISBN: 0822386380
Category : Psychology
Languages : en
Pages : 137

Book Description
How can scientific theories contribute to contemporary accounts of embodiment in the humanities and social sciences? In particular, how does neuroscientific research facilitate new approaches to theories of mind and body? Feminists have frequently criticized the neurosciences for biological reductionism, yet, Elizabeth A. Wilson argues, neurological theories—especially certain accounts of depression, sexuality, and emotion—are useful to feminist theories of the body. Rather than pointing toward the conventionalizing tendencies of the neurosciences, Wilson emphasizes their capacity for reinvention and transformation. Focusing on the details of neuronal connections, subcortical pathways, and reflex actions, she suggests that the central and peripheral nervous systems are powerfully allied with sexuality, the affects, emotional states, cognitive appetites, and other organs and bodies in ways not fully appreciated in the feminist literature. Whether reflecting on Simon LeVay’s hypothesis about the brains of gay men, Peter Kramer’s model of depression, or Charles Darwin’s account of trembling and blushing, Wilson is able to show how the neurosciences can be used to reinvigorate feminist theories of the body.

Trending Topics in Multiple Sclerosis

Trending Topics in Multiple Sclerosis PDF Author: Alina Gonzalez-Quevedo
Publisher: BoD – Books on Demand
ISBN: 9535126563
Category : Medical
Languages : en
Pages : 340

Book Description
Multiple sclerosis (MS) is a chronic inflammatory disease characterized by progressive demyelination and neurodegeneration of the central nervous system (CNS), constituting the most common demyelinating disease of the CNS in humans. Although intensive research over many decades has unveiled many pathophysiological mechanisms in the development of MS, the cause is still unknown. Nevertheless, it does seem clear that genetic susceptibility and environmental factors play crucial roles. Trending Topics in Multiple Sclerosis is a book that provides an insight into some of the main problems currently debated in this area of research, focusing on topics that deal with genetic and environmental risk factors, pathophysiological mechanisms, neurocognitive findings, and neuroprotective strategies.

Conditioned Reflexes

Conditioned Reflexes PDF Author: I. P. Pavlov
Publisher: Courier Corporation
ISBN: 0486161218
Category : Psychology
Languages : en
Pages : 470

Book Description
The Nobel Prize-winning scientist offers a precise, full, and accessible exposition of his landmark work in experimental psychology. Pavlov details the technical means by which he established experiments and controls, the experiments, observations on formation of conditioned reflexes, external and internal reflex inhibitions, the function of cerebral hemispheres and cortex, and more. 18 figures.

New Insights Into Mechanotransduction by Immune Cells in Physiological and Pathological Conditions

New Insights Into Mechanotransduction by Immune Cells in Physiological and Pathological Conditions PDF Author: Shaik O. Rahaman
Publisher: Frontiers Media SA
ISBN: 2889763390
Category : Medical
Languages : en
Pages : 119

Book Description