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Author: William E. Paul Publisher: Lippincott Williams & Wilkins ISBN: 1451182031 Category : Medical Languages : en Pages : 1313
Book Description
This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book’s fully revised and updated content reflects the latest advances in the field. Current insights enhance readers’ understanding of immune system function. The text’s unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text and image bank! This is the tablet version of Fundamental Immunology which does not include access to the supplemental content mentioned in the text.
Author: Otto G. Bier Publisher: Springer Science & Business Media ISBN: 3642703933 Category : Medical Languages : en Pages : 474
Book Description
The good acceptance of this textbook is an indication that it has served its purpose. The present edition has been prepared in order to cover the main progress achieved in the five years that have elapsed since the first edition. The structure of the book remains essentially the same but a con siderable amount of new material has been introduced, particularly in certain areas such as the genetics of immunoglobulins and T cell receptor, the regulation of the immune response, hypersensitivity reactions, and cellular immunology. Today, immunology is essential for biologists in general and in particular for physicians, veterinarians, and pathologists. The great progress and diversification that has taken place in the last few years is due to its enormous value both for the understanding of theoretical biology and for the practical resolution of biochemical, genetic, pathological, and biological problems. Greatly contributing to this progress have been relatively sophisticated techniques, such as immunofluorescence, radioimmune assay, transmission electron micro scopy, scanning electron microscopy, isoelectric focusing, quantitative cytofluorimetry, affinity chromatography, and techniques that allow separation of the different lymphocyte subpopulations. A potentially fabulous field was recently opened with the development of techniques for obtaining monoclonal antibodies by fusion of immunologically active lymphocytes with myeloma cells. These hybrid cells produce large amounts of monoclonal antibodies or other lymphocyte factors. The establishment of this hybridoma technology, that is already routine in most laboratories, is being used in the resolution of general biology problems, particularly in the study of the various cell surface molecules.
Author: William E. Paul Publisher: Lippincott Williams & Wilkins ISBN: 1451117833 Category : Medical Languages : en Pages : 1313
Book Description
Fundamental Immunology Seventh Edition This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book's fully revised and updated content reflects the latest advances in the field. Current insights enhance readers' understanding of immune system function. The text's unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed. Look inside and discover... * Fully revised and updated content reflects the latest advances in the field. * Current insights enhance readers' understanding of immune system function * Unique approach bridges the gap between basic immunology and the disease process. * Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. * Abundant illustrations and tables deliver essential information at a glance. PLUS... A convenient companion website features the fully searchable text with all references linked to PubMed. Pick up your copy today!
Author: Manzoor Ahmad Mir Publisher: ISBN: 9781536166392 Category : Languages : en Pages :
Book Description
Immunology is a distinctive subject that rose in the mid-20th century. The subject developed as scientists started to unravel the mysteries about the defense system against pathogens. Researchers started to understand the mechanisms employed by the innate and the adaptive immune system in defense against pathogens. During the last decade, the subject of immunology has been in sharp focus as the immunotherapies against diseases like cancer and AIDS seems last hope. Employing the body's own defense system against diseases like cancer and AIDS by activating specific cells of the immune system looks promising, and therapies like CAR-T cell therapy have been approved. In the first edition of the book "The Fundamentals of Immunology" we have explained the basics of the defense system of our body. The book is organised into four volumes. The first volume comprises of ten chapters and it describes the rise, history and scope of immunology and the building blocks of the immune system viz., cells, molecules and organs of the immune system. The second chapter describes the cells of the innate and the adaptive immune system and how the granulocytes and macrophages employ defense mechanisms to protect the body against pathogenic invasions. In the third chapter of this book, we have described the organs of the immune systems and how different organs are involved in the differentiation and maturation of immune cells. The chapter also focused on the structure of lymph nodes and their function in concentrating the antigens. In chapter four of this book, we have described the terms like antigens, immunogens, antigenicity, immunogenicity and how immunogenicity of an antigen is affected and how antigenicity of an immunogens is related to the immune response. The innate and adaptive immune systems and the different types of cells and molecules employed by the two branches of immunity have been described in a separate chapter. The structure and biology of immunoglobulins, their types and function in antigen binding and antibody dependent cellular cytotoxicity (ADCC) have been described well in chapter six. Focus has been laid on the distinction between an antibody and an immunoglobulin. The structure and function and major histocompatibility complex (MHC) has been described. The education of cells about self and non-self during their maturation and the processing and presentation of antigens by MHC bearing cells and how MHC coordinates both humoral and cell-mediated immune responses has been explained well throughout the book. The book has explained the complement system and its components, mechanisms and functions in a separate chapter. At the end of the book, we have given an insight about the vaccines, their history, development and how they are useful and helpful in the defense against diseases. The book also discusses the immune disfunction and diseases associated with the dysregulation of immune responses.
Author: Martin Flajnik Publisher: Lippincott Williams & Wilkins ISBN: 1975142527 Category : Medical Languages : en Pages : 3597
Book Description
Selected as a Doody's Core Title for 2022! Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.
Author: William E. Paul Publisher: Lippincott Williams & Wilkins ISBN: 1451182031 Category : Medical Languages : en Pages : 1313
Book Description
This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book’s fully revised and updated content reflects the latest advances in the field. Current insights enhance readers’ understanding of immune system function. The text’s unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text and image bank! This is the tablet version of Fundamental Immunology which does not include access to the supplemental content mentioned in the text.
Author: O.G. Bier Publisher: Springer Science & Business Media ISBN: 1468401165 Category : Medical Languages : en Pages : 442
Book Description
This textbook of basic and clinical immunology has been written primarily for medical and biology students who are receiving their first introduction to this fascinating field. Although we have presumed some knowledge of basic biology (particularly physiology and biochemistry), our primary intent has not been to cover in depth the latest research findings. Rather, we have sought to lay a firm foundation for subsequent reading in the laboratory and clinical sciences: internal medicine, pediatrics, microbiology, serology, physiology, cell biology, and genetics. Hence the first part of the text presents the various components of basic immunology, while the second shows how these elements interact under both normal physiologic and pathologic condi tions. To facilitate comprehension of the relationship between basic and clinical immunology, we have introduced cross-references throughout the book. A glossary of important terms has also been included. Selected references are provided with each chapter to guide the student to additional information on topics of special interest. Throughout the book we have attempted to convey to new students of immunology some of the excitement which the subject has long held for us. If we have succeeded, the task of writing will have been worthwhile.
Author: Angela Hall Publisher: Oxford University Press, USA ISBN: 0199534969 Category : Medical Languages : en Pages : 288
Book Description
Immunology gives the new biomedical scientist an insight into the function of the immune system, the front line of defence against pathological disease, and the diagnostic techniques used to identify associated malfunctions and disorders.