Fundamentals of Evidence-Based Health Care and Translational Science PDF Download

Author: Francesco Chiappelli
Publisher:
ISBN: 9783642418587
Category :
Languages : en
Pages : 424

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Author: Francesco Chiapelli
Publisher:
ISBN: 9781536145984
Category : Medical care
Languages : en
Pages : 0

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Book Description
The future of healthcare lies in the continued progress and acceleration of adopting translational science. The two principal constructs, translational research and translational effectiveness, collectively strive towards patient-centered, effectiveness-focused and evidence-based care. Translational research is the application of scientific methods into healthcare decision-making and practice. Through these applications and methods used on the patient, translational research obtains new information that directly benefits that patient in return. This bench-to-bedside approach is specifically designed to improve health outcomes and standards of practice in healthcare to better serve the patients. It is through the utilization, dissemination, and implementation of the best evidence-based practices that will help in the understanding of intervention effectiveness. The chapters in this book highlight the transfer of basic science discovered and cutting-edge developments into clinical applications. Emphasis on continuing research, increasing transparency and accelerating the adoption of translational science into clinical practice is needed to provide the best possible care. The chapters focus on the future direction of all fields of healthcare which lies on the bench-to-bedside approach from medicine to dentistry to nursing. Translational research is at the forefront of efforts to improve patient care and is the engine of change for bringing new decision-making, practice, and technology into the field of healthcare in this new age.

Author:
Publisher:
ISBN: 9781451161687
Category : Evidence-based medicine
Languages : en
Pages : 65

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Book Description
This book seeks to examine the translational research process in relation to the JBI Model of Evidence Based Health Care and to clarify how the three translation gaps identified in the text and the elements of the JBI Model serve to complement each other in modelling the relationship between the translation science cycle and the pragmatic evidence-based healthcare cycle.

Author: Barbara Alving
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318022845
Category : Science
Languages : en
Pages : 136

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Book Description
This book is the first to provide an aerial view, as well as detailed information, on 'how' activities in translational medicine are under development in countries such as the USA, China, the UK, and Taiwan. Institutions in each country are training investigators to work as sophisticated interdisciplinary teams. Investigators from 11 US academic health centers explain how they are incentivizing collaborations through pilot project programs, forming partnerships with business schools to promote efficient management of basic and clinical research, creating ethical, high- value public-private (industry) partnerships, improving efficiency with utilization of informatics, and engaging the community in research. The essential role of evaluation is explained in a clear and concise manner. The readers will also learn about the role of private funding in Taiwan and the vision of the government in China in developing multiple translational research centers. The UK is developing methodical approaches to patient needs across their lifespans; ongoing innovation is encouraged through incubator programs. With the emphasis on open innovation and sharing, the concepts and practice of translational medicine are spreading rapidly on an international scale.

Author: Sharon E. Straus
Publisher: John Wiley & Sons
ISBN: 1118413571
Category : Medical
Languages : en
Pages : 296

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Book Description
Knowledge Translation in Health Care is a practical introduction to knowledge translation for everyone working and learning within health policy and funding agencies, and as researchers, clinicians and trainees. Using everyday examples, it explains how to use research findings to improve health care in real life. This new second edition defines the principles and practice of knowledge translation and outlines strategies for successful knowledge translation in practice and policy making. It includes relevant real world examples and cases of knowledge translation in action that are accessible and relevant for all stakeholders including clinicians, health policy makers, administrators, managers, researchers, clinicians and trainees. From an international expert editor and contributor team, and fully revised to reflect current practice and latest developments within the field, Knowledge Translation in Health Care is the practical guide for all health policy makers and researchers, clinicians, trainee clinicians, medical students and other healthcare professionals seeking to improve healthcare practice.

Author: David Robertson
Publisher: Academic Press
ISBN: 012802111X
Category : Science
Languages : en
Pages : 812

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Book Description
Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

Author:
Publisher:
ISBN: 9783642050442
Category :
Languages : en
Pages : 268

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Author: Kameshwar Prasad
Publisher: Springer Science & Business Media
ISBN: 8132208315
Category : Medical
Languages : en
Pages : 165

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Book Description
This is a basic book on evidence-based medicine (EBM). It starts with an introduction to the topic. It outlines the relationship between EBM and research and quality of care. Then It goes on to cover the most commonly used modules of EBM, i.e. therapy, diagnosis, prognosis and meta-analysis. Each module starts with an introduction to fundamental concepts, and description of the related research process, and then follows the critical appraisal of related type of research artcle. At the end, it covers the different systems of grading of level of evidence and strength of recommendations. The book also has three examples of critical appraisal on diagnosis, therapy, and meta-analysis.​

Author: Francesco Chiappelli
Publisher: Springer Science & Business Media
ISBN: 3642418570
Category : Medical
Languages : en
Pages : 413

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Book Description
Comparative effectiveness research – the conduct and synthesis of systematic research in order to compare the benefits and harms of alternative treatment options – is of critical importance in enabling informed health care decisions to be made. This user-friendly, practical handbook examines in depth how best to perform such comparative effectiveness research. A wide range of topics and methods are discussed, including research synthesis, sampling analysis, assessment of evidence design, systematic evaluation of statistical analysis, and meta-analysis. The discussion extends well beyond the fundamentals by encompassing “complex” systematic reviews, “cumulative” meta-analyses, and logic-based versus utility-based decision making. Health care providers, researchers, instructors, and students will all find this to be an invaluable reference on the compelling current issues and important analytical tools in comparative effectiveness research.

Author: Thomas L. Christenbery, PhD, RN, CNE
Publisher: Springer Publishing Company
ISBN: 0826127592
Category : Medical
Languages : en
Pages : 392

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Book Description
A fundamental, reader-friendly guide to evidence-based practice (EBP) for BSN, MSN, and DNP nursing students, Evidence-Based Practice in Nursing explains the conceptual underpinnings of EBP and demonstrates how nurses can put EBP concepts into practice. Replete with critical knowledge, skills, tools, and scholarly development to enable nurses to fully and confidently deliver the highest-quality EBP care, this book eschews a one-size-fits-all approach unique systematic guidelines for understanding and applying EBP. Building blocks of information grow progressively more complex to apply to any point along nursing’s academic trajectory. Thoughtfully organized to fit a variety of EBP-related course objectives, Evidence Based Practice in Nursing easily adapts for standalone EBP courses at any level as well as advanced practice specialty courses that integrate EBP content. This book addresses the needs of all nursing instructors, including those who teach at multiple levels simultaneously. Key content discusses requisite conceptual knowledge of EBP for building clinical decision-making skills; conceptualizing, implementing, and evaluating EBP projects; conducting translational research and quality improvement for implementation and evaluation of EBP; developing leadership and structural empowerment strategies; and analyzing how students at each degree/level work with EBP independently, inter-professionally, and intraprofessionally. Chapters align with AACN essentials. Key Features: Follows a methodical systematic trajectory building from simple to complex concepts Includes abundant examples demonstrating both negative and positive EBP applications Enables instructors to adopt one textbook for BSN, MSN, and DNP students Includes practical design templates for developing EBP information plans with critical guideposts Provides a quality improvement toolkit, key words and concepts, illustrative tables, and figures