Functional surfaces and biomaterials PDF Download

Author: Yuangang Liu
Publisher: Frontiers Media SA
ISBN: 2832515061
Category : Science
Languages : en
Pages : 257

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Author: Rachel Williams
Publisher: Elsevier
ISBN: 0857090763
Category : Medical
Languages : en
Pages : 438

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Book Description
The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a material's surface can be tailored to improve biocompatibility, adhesion and cell interactions. Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface modification of biomaterials reviews both established surface modifications and those still in the early stages of research and discusses how they can be used to optimise biological interactions and enhance clinical performance.Part one begins with chapters looking at various types and techniques of surface modification including plasma polymerisation, covalent binding of poly (ethylene glycol) (PEG), heparinisation, peptide functionalisation and calcium phosphate deposition before going on to examine metal surface oxidation and biomaterial surface topography to control cellular response with particular reference to technologies, cell behaviour and biomedical applications. Part two studies the analytical techniques and applications of surface modification with chapters on analysing biomaterial surface chemistry, surface structure, morphology and topography before moving onto discuss modifying biomaterial surfaces to optimise interactions with blood, control infection, optimise interactions with soft tissues, repair and regenerate nerve cells, control stem cell growth and differentiation and to optimise interactions with bone.The distinguished editor and international team of contributors to Surface modification of biomaterials have produced a unique overview and detailed chapters on a range of surface modification techniques which will provide an excellent resource for biomaterials researchers and scientists and engineers concerned with improving the properties of biomaterials. It will also be beneficial for academics researching surface modification. - Reviews both established surface modifications and those still in the early stages of research and how they can be used to optimise biological interactions and enhance clinical performance - Studies analytical techniques and applications of surface modification with chapters assessing biomaterial surface chemistry, surface structure, morphology and topography - Discusses modifying biomaterial surfaces to optimise interactions with blood and soft tissues and also to repair and regenerate nerve cells and control infection

Author: Rui Vilar
Publisher: Woodhead Publishing
ISBN: 0081009429
Category : Technology & Engineering
Languages : en
Pages : 352

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Book Description
Laser Surface Modification of Biomaterials: Techniques and Applications covers this expanding field, which has many potential applications, including biomaterials. Laser surface modification of biomaterials enables the production of hybrid materials with different functionality in the bulk as well as the thin, sub-micrometer surface layer. This book will provide readers with a comprehensive review of the technology and its applications. Chapters in Part 1 look at the techniques and considerations of laser surface modification, while Part 2 reviews laser surface modification techniques of the most important classes of biomaterials, with a final set of chapters discussing application specific laser surface modification. - Offers a comprehensive review of laser surface modification techniques - Presents recent developments, fundamentals, and progress in laser surface modification - Reviews laser surface modification applications across a range of materials - Emphasizes applications in biomaterials

Author: Tamilselvan Mohan
Publisher: John Wiley & Sons
ISBN: 3527827668
Category : Technology & Engineering
Languages : en
Pages : 718

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Book Description
A succinct handbook explaining interdisciplinary processing, methods, and applications of bio-based materials This book merges the two most important trends in biomaterials: functionalization and renewable chemistry. It covers a variety of biopolymers and various approaches for the transformation of these biopolymers into functional units. Sample topics covered by the two well-qualified authors include: Fundamental knowledge of biopolymers–natural ones, such as cellulose and other polysaccharides, and synthetic ones, such as polyethylene The origin, classifications, chemical nature, and isolation methods of specific biopolymers The different classical and modern approaches for the transformation of biopolymers into different shapes, ranging from thin films (model surfaces), to nanoparticles, to nanofibers, all the way to 3D scaffolds The morphology, structure, shape, thermal, electrical, and surface properties of biomaterials This all-inclusive reference guide, which covers fundamentals, methods, and applications alike, is a key resource for both students and practicing scientists involved in programs of study or disciplines that intersect with the field of biomaterials.

Author: Ajaykumar Vishwakarma
Publisher: Academic Press
ISBN: 0128027568
Category : Science
Languages : en
Pages : 644

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Book Description
Biology and Engineering of Stem Cell Niches covers a wide spectrum of research and current knowledge on embryonic and adult stem cell niches, focusing on the understanding of stem cell niche molecules and signaling mechanisms, including cell-cell/cell-matrix interactions. The book comprehensively reviews factors regulating stem cell behavior and the corresponding approaches for understanding the subsequent effect of providing the proper matrix molecules, mechanical cues, and/or chemical cues. It encompasses a variety of tools and techniques for developing biomaterials-based methods to model synthetic stem cell niches in vivo, or to enhance and direct stem cell fate in vitro. A final section of the book discusses stem cell niche bioengineering strategies and current advances in each tissue type. - Includes the importance of Cell-Cell and Cell Matrix Interactions in each specific tissue and system - Authored and edited by authorities in this emerging and multidisciplinary field - Includes valuable links to 5-10 minute YouTube© author videos that describe main points

Author: Christopher Siedlecki
Publisher: Woodhead Publishing
ISBN: 0081004990
Category : Science
Languages : en
Pages : 486

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Book Description
Hemocompatibility of Biomaterials for Clinical Applications: Blood-Biomaterials Interactions summarizes the state-of-the-art on this important subject. The first part of the book reviews the latest research on blood composition and response, mechanisms of coagulation, test standards and methods. Next, the book assesses techniques for modifying biomaterial surfaces and developing coatings to improve hemocompatibility. In the final sections, users will find discussions on ways to improve the hemocompatibility of particular classes of biomaterials and a review of methods for improving medical devices. - Provides comprehensive information on the fundamentals of hemocompatibility and new technologies - Combines research in the biomaterials field in a digestible format for clinical applications - Provides a complete overview biomaterials in current use and test methods

Author: Syed Tofail
Publisher: Royal Society of Chemistry
ISBN: 1849733368
Category : Technology & Engineering
Languages : en
Pages : 277

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Book Description
When a biomaterial is placed inside the body, a biological response is triggered almost instantaneously. With devices that need to remain in the body for long periods, such interactions can cause encrustation, plaque formation and aseptic loosening on the surface. These problems contribute to the patient's trauma and increase the risk of death. Electrical properties, such as local electrostatic charge distribution, play a significant role in defining biological interactions, although this is often masked by other factors. This book describes the fundamental principles of this phenomenon before providing a more detailed scientific background. It covers the development of the relevant technologies and their applications in therapeutic devices such as MRSA-resistant fabrics, cardiovascular and urological stents, orthopaedic implants, and grafts. Academic and graduate students interested in producing a selective biological response at the surface of a given biomaterial will find the detailed coverage of interactions at the nanometre scale useful. Practitioners will also benefit from guidance on how to pre-screen many inappropriate designs of biomedical devices long before any expensive, animal or potentially risky clinical trials. Enhanced by the use of case studies, the book is divided in to four topical sections. The final section is dedicated to the application of related topics making the book unique in its pragmatic approach to combining high end interdisciplinary scientific knowledge with commercially viable new technologies. Contributing to the newly emerging discipline of 'nanomedicine', the book is written not only by experts from each relevant specialty but also by practitioners such as clinicians and device engineers from industry.

Author: Buddy D. Ratner
Publisher: Springer Science & Business Media
ISBN: 9780306455124
Category : Medical
Languages : en
Pages : 214

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Book Description
Proceedings of the American Chemical Society Division of Polymer Chemistry International Symposium held in Anaheim, California, April 2-6, 1995

Author: Manjie Zhang
Publisher: Frontiers Media SA
ISBN: 2832552196
Category : Science
Languages : en
Pages : 154

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Book Description
Early diagnosis of cancer is still a major challenge in cancer therapy. In recent years, the development of multifunctional nanomaterials has provided a new diagnosis and treatment platform to combat cancer. Polymer-inorganic nanomaterials with novel structures such as bowl-shaped/Janus/core-shell have drawn much attention owing to their diversity in composition or asymmetry in structure. More importantly, imparting unique optical, electrical, and magnetic properties to these nanocomposites can further extend their function repertoire. However, to fulfill this vision, fundamental understandings regarding strategies of precise synthesis, mechanisms of structure formation, in vivo synergistic effects in bioapplications, and biosafety of these materials are needed. Besides, nanomaterials with novel structures are well positioned for imaging-guided cancer theranostic. On one hand, nanomaterials themselves are suitable for imaging because of their intrinsic properties such as fluorescent or magnetic properties. On the other hand, nanomaterials can serve as functional platforms that integrate various therapeutic modalities including photothermal therapy, chemodynamic/ion-interference therapy, photodynamic therapy, and cuproptosis to efficiently kill cancer cells. This Research Topic aims at collecting works about synthesis, and biomedical applications of polymer/mesoporous inorganic nanomaterials, especially in the aspect of novel synthetic approaches for fabricating nanomaterials with unique structures. Additionally, we hope that in-depth research articles on this topic can provide insights into the mechanism of nanomaterials acting in cancer diagnosis and therapy. These include the mechanisms of customized drug load/release and synergistic effects in theranostics of these materials. Meanwhile, elucidations of key proteins’ roles in cancer development are also anticipated. Lastly, we hope that this topic can brew new ideas for the adaption of nanomaterials as platforms that allow for multimodal therapeutic modalities. The current Research Topic centers on the design, precise synthesis, and biomedical applications of nanomaterials. It aims to cover novel and promising research trends in nanomaterials with different morphology for cancer theranostics. Manuscripts from the following aspects, but not limited to, are welcomed: • Tailoring of asymmetrically structured (bowl-shaped, Janus, Yin Yang-like) polymer-inorganic nanomaterials; • Inorganic functional nanocrystals and functionalized mesoporous nanomaterials; • Design and synthesis of functional biomaterials, including lipids, polymers, and 2D materials • Non-viral DNA/mRNA delivery or drug/molecular inhibitor delivery; • Synthesizing biomaterials with novel nanostructures such as bowl-shaped, core-shell, spherical, Janus, and quantum dots; • Conquering drug resistance issues, tumor metastasis, and recurrence, as well as designing combination nanomedicines; • Dissecting the role of menin in prostate cancer and breast cancer: crosstalk between menin and AR signaling; • Multi-stimulus-responsive drug release and biological molecules.

Author: Ajit Behera
Publisher: CRC Press
ISBN: 1003848346
Category : Technology & Engineering
Languages : en
Pages : 641

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Book Description
Surface engineering provides one of the most important means of engineering product differentiation in terms of quality, performance, and lifecycle cost. It is essential to achieve predetermined functional properties of materials such as mechanical strength, biocompatibility, corrosion resistance, wear resistance, and heat and oxidation resistance. Surface Engineering of Biomaterials addresses this topic across a diverse range of process technologies and healthcare applications. Introduces biomaterial surface science and surface engineering and includes criteria for biomaterial surface selection Focuses on a broad array of materials including metals, ceramics, polymers, alloys, and composites Discusses corrosion, degradation, and material release issues in implant materials Covers various processing routes to develop biomaterial surfaces, including for smart and energy applications Details techniques for post-modification of biomaterial surfaces This reference work helps researchers working at the intersection of materials science and biotechnology to engineer functional biomaterials for a variety of applications.