Author: Ann-Marie CarberyPublisher:
ISBN:
Category :
Languages : en
Pages : 267
Book Description
Function of Suppressor of Deltex During Drosophila Oogenesis
Author: Ann-Marie CarberyRole of Deltex in Drosophila Oogenesis
Author: Yvonne Hue Yee HungThe Regulation and Function of Daughterless During Drosophila Oogenesis
Author: John Edward SmithNotch Signaling in Embryology and Cancer
Author: Jörg ReichrathPublisher: Springer Nature
ISBN: 3030550311
Category : Medical
Languages : en
Pages : 228
Book Description
This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more. Taken as a whole, with its companion books -- Notch Signaling and Embryologic Development and Molecular Basis of Notch Signaling – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.
Molecular Mechanisms of Notch Signaling
Author: Tilman BorggrefePublisher: Springer
ISBN: 3319895125
Category : Science
Languages : en
Pages : 417
Book Description
This book describes the Notch signaling pathway with a focus on molecular mechanisms. The Notch signaling pathway is a seemingly simple pathway that does not involve any second messenger. Upon ligand binding two consecutive proteolytic cleavages of the NOTCH receptor release the Notch intracellular domain from the membrane. The Notch intracellular domain migrates into the nucleus and activates gene expression. Recently, new technologies allowed us to better understand this pivotal signaling cascade and revealed new regulatory mechanisms. The different chapters cover many aspects of the Notch signaling focusing on the mechanisms governing the receptor/ligand interaction as well as on the downstream intracellular signaling events. Aspects of both canonical and non-canonical signaling are discussed and the function of Notch signaling in physiological and pathological contexts are elucidated. This book is not only intended for experts but it should also be a useful resource for young, sprouting scientists or interested scientists from other research areas, who may use this book as a stimulating starting point for further discoveries and developments.
Entomology Abstracts
Author: Chemical Abstracts
Author: The Analysis of a Case of Continuous Variation in Drosophila by a Study of Its Linkage Relations ...
Author: John Smith DexterPublisher:
ISBN:
Category : Animals
Languages : en
Pages : 58
Book Description
Index Medicus
Author: Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 2454
Book Description
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author: