Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download From Sound to Synapse PDF full book. Access full book title From Sound to Synapse by C. Daniel Geisler. Download full books in PDF and EPUB format.
Author: C. Daniel Geisler Publisher: Oxford University Press, USA ISBN: 9780195100259 Category : Medical Languages : en Pages : 410
Book Description
This comprehensive introduction to the functions of the mammalian ear describes the major steps by which sound is transformed into nerve impulses. The author leads the reader along the pathway followed by the acoustic signal. He starts with the collection of sound by the outer ear, proceeds to its transfer by the middle ear, and finally analyzes its modification in the inner ear, where the sound waves are transformed into nerve impulses. The book concludes with descriptions of some common ear impairments and a brief survey of the treatments available for them. At each stage of the ear's sound processing, Professor Geisler discusses the basic mechanisms, covering current theories and illustrating the discussions with experimental data. Although he uses an extensive array of analogies and mathematical models, he considers only the basic theory and the outputs of the models, not their derivation or formal usage. Where appropriate, related mechanisms in the ears of other vertebrates are considered. From Sound to Synapse is written in lucid, accessible style that makes no assumptions about the scientific background of the reader apart from a basic familiarity with pulse generation by neurons. It will be of value to researchers and students in sensory physiology, neurophysiology, acoustics, bioengineering, psychoacoustics, and neuroscience. It will also benefit neurologists, audiologists, otolaryngologists, and other clinicians interested in a more detailed description of sound processing.
Author: C. Daniel Geisler Publisher: Oxford University Press, USA ISBN: 9780195100259 Category : Medical Languages : en Pages : 410
Book Description
This comprehensive introduction to the functions of the mammalian ear describes the major steps by which sound is transformed into nerve impulses. The author leads the reader along the pathway followed by the acoustic signal. He starts with the collection of sound by the outer ear, proceeds to its transfer by the middle ear, and finally analyzes its modification in the inner ear, where the sound waves are transformed into nerve impulses. The book concludes with descriptions of some common ear impairments and a brief survey of the treatments available for them. At each stage of the ear's sound processing, Professor Geisler discusses the basic mechanisms, covering current theories and illustrating the discussions with experimental data. Although he uses an extensive array of analogies and mathematical models, he considers only the basic theory and the outputs of the models, not their derivation or formal usage. Where appropriate, related mechanisms in the ears of other vertebrates are considered. From Sound to Synapse is written in lucid, accessible style that makes no assumptions about the scientific background of the reader apart from a basic familiarity with pulse generation by neurons. It will be of value to researchers and students in sensory physiology, neurophysiology, acoustics, bioengineering, psychoacoustics, and neuroscience. It will also benefit neurologists, audiologists, otolaryngologists, and other clinicians interested in a more detailed description of sound processing.
Author: Laurence O. Trussell Publisher: Springer Science & Business Media ISBN: 144199517X Category : Science Languages : en Pages : 242
Book Description
Synaptic Mechanisms in the Auditory System will provide a basic reference for students, clinicians, and researchers on how synapses in the auditory system function to encode acoustic signals. These mechanisms are the groundwork for all auditory processing, and understanding them requires knowledge of the microphysiology of synapses, cellular biophysics, receptor pharmacology, and an appreciation for what these synapses must do for a living, what unique jobs they carry out.
Author: Özge Demet Özçete Publisher: ISBN: Category : Languages : en Pages : 0
Book Description
The inner hair cell (IHC) synapse, the first relay station of the auditory system, is able to encode sound with sub-millisecond precision and without any signs of fatigue (Matthews and Fuchs, 2010; Pangršicˇ et al., 2012; Safieddine et al., 2012). Consequently, the IHC synapse manages a high rate of neurotransmitter release per active zone (AZ), which requires a fine balance between fast exocytosis and subsequent endocytosis (Pangrsic et al., 2010; Pangrsic and Vogl, 2018). The molecular physiology of this synapse is unconventional and far from understood. Furthermore, for a given sound fre...
Author: Stefanie Krinner Publisher: ISBN: Category : Languages : en Pages :
Book Description
To achieve accurate encoding of sounds, inner hair cell (IHC) ribbon-type synapses are highly specialized to release synaptic vesicles (SVs) with high rates and temporal precision. A sophisticated, by far not yet fully disentangled unconventional molecular machinery at the synapse active zone (AZ) realizes this impressive performance. It regulates the number of synaptic CaV1.3 Ca2+-channels, their tight coupling to SVs, and fast re-supply of SVs for sustained rates of exocytosis. Sound-evoked glutamate release from an IHC synapse is sensed by the postsynaptic spiral ganglion neurons (SGNs)....
Author: Laurence O. Trussell Publisher: Springer ISBN: 9781441995186 Category : Science Languages : en Pages : 234
Book Description
Synaptic Mechanisms in the Auditory System will provide a basic reference for students, clinicians, and researchers on how synapses in the auditory system function to encode acoustic signals. These mechanisms are the groundwork for all auditory processing, and understanding them requires knowledge of the microphysiology of synapses, cellular biophysics, receptor pharmacology, and an appreciation for what these synapses must do for a living, what unique jobs they carry out.
Author: Gokhan Dalgin Publisher: Frontiers Media SA ISBN: 2889632482 Category : Languages : en Pages : 157
Book Description
There are only a few vertebrate systems that can be used to model human diseases for biomedical discovery. The zebrafish model provides key advantages over existing models. Their externally developing embryos provide high-throughput non-invasive imaging, chemical screening, forward and reverse genetics, and their regeneration capacity make zebrafish a valuable system for novel discovery. Developmental studies using zebrafish has influenced discoveries in many human health-related conditions. This Research Topic covers all aspects of zebrafish studies, providing developmental mechanisms to human health conditions. The aim of the Research Topic was to foster a platform to bring all levels of zebrafish research including but not limited to development, disease, regeneration, drug screening, bioinformatics and Omics studies.
Author: Karam F.A. Soliman Publisher: CRC Press ISBN: 1000835200 Category : Medical Languages : en Pages : 293
Book Description
The nuclear factor erythroid 2-related factor 2 (Nrf2) was described as a master regulator of the cellular antioxidant response. Moreover, many critical biological functions linked to cell viability, metabolism, autophagy, inflammation, immunity, and differentiation have been attributed to Nrf2, which regulates over 600 genes. It is well known that oxidative stress, which Nrf2 can ameliorate, plays a key role in many pathologic processes such as aging, obesity, diabetes, cancer, and neurodegenerative diseases. Flavonoids, on the other hand, through their ability to activate and upregulate Nrf2, can have anti-oxidative, anti-inflammatory, anti-mutagenic, and anti-carcinogenic properties. Flavonoids are an essential ingredient in nutraceuticals, functional foods, and pharmaceuticals. The present book Flavonoids and Anti-Aging: The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2 focuses on the interaction between Nrf2 and flavonoids and their applications in various conditions such as aging, osteoporosis, cardiovascular diseases, and neurodegenerative disease and many other areas. Key Features: Focuses on the mechanisms and use of flavonoids in activating Nrf2 as an anti-aging and "WELLNESS" molecule Provides a specific approach to flavonoid activation of Nrf2 and its implications in aging and various disease conditions and its applications as nutraceuticals Presents flavonoid-based functional foods Discusses the flavonoid nutraceuticals market and future trends Written by experts in the field, this book provides a unique approach to understanding the flavonoid activation of the transcription factor Nrf2, which is responsible for many different disease conditions due to increased reactive oxidative species in the body caused by some physiological triggers.
Author: Enrico Coen Publisher: Princeton University Press ISBN: 0691149674 Category : Education Languages : en Pages : 342
Book Description
A compelling investigation into the relationships between our biological past and cultural progress, "Cells to Civilizations" presents a remarkable story of living change.
Author: David Sulzer Publisher: Columbia University Press ISBN: 0231550502 Category : Mathematics Languages : en Pages : 180
Book Description
Why does a clarinet play at lower pitches than a flute? What does it mean for sounds to be in or out of tune? How are emotions carried by music? Do other animals perceive sound like we do? How might a musician use math to come up with new ideas? This book offers a lively exploration of the mathematics, physics, and neuroscience that underlie music in a way that readers without scientific background can follow. David Sulzer, also known in the musical world as Dave Soldier, explains why the perception of music encompasses the physics of sound, the functions of the ear and deep-brain auditory pathways, and the physiology of emotion. He delves into topics such as the math by which musical scales, rhythms, tuning, and harmonies are derived, from the days of Pythagoras to technological manipulation of sound waves. Sulzer ranges from styles from around the world to canonical composers to hip-hop, the history of experimental music, and animal sound by songbirds, cetaceans, bats, and insects. He makes accessible a vast range of material, helping readers discover the universal principles behind the music they find meaningful. Written for musicians and music lovers with any level of science and math proficiency, including none, Music, Math, and Mind demystifies how music works while testifying to its beauty and wonder.
Author: C. Daniel Geisler
Author: C. Daniel Geisler
Author: Laurence O. Trussell
Author: Özge Demet Özçete
Author: Stefanie Krinner
Author: Laurence O. Trussell
Author: Tejbeer Kaur
Author: Gokhan Dalgin
Author: Karam F.A. Soliman
Author: Enrico Coen
Author: David Sulzer