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Author: Francisco José Galindo-Rosales Publisher: Springer ISBN: 3319595938 Category : Technology & Engineering Languages : en Pages : 116
Book Description
This monograph contains expert knowledge on complex fluid-flows in microfluidic devices. The topical spectrum includes, but is not limited to, aspects such as the analysis, experimental characterization, numerical simulations and numerical optimization. The target audience primarily comprises researchers who intend to embark on activities in microfluidics. The book can also be beneficial as supplementary reading in graduate courses.
Author: Yu Song Publisher: John Wiley & Sons ISBN: 3527341064 Category : Science Languages : en Pages : 576
Book Description
The first book offering a global overview of fundamental microfluidics and the wide range of possible applications, for example, in chemistry, biology, and biomedical science. As such, it summarizes recent progress in microfluidics, including its origin and development, the theoretical fundamentals, and fabrication techniques for microfluidic devices. The book also comprehensively covers the fluid mechanics, physics and chemistry as well as applications in such different fields as detection and synthesis of inorganic and organic materials. A useful reference for non-specialists and a basic guideline for research scientists and technicians already active in this field or intending to work in microfluidics.
Author: Eric Brouzes Publisher: MDPI ISBN: 3036501843 Category : Science Languages : en Pages : 114
Book Description
Droplet microfluidics has dramatically developed in the past decade and has been established as a microfluidic technology that can translate into commercial products. Its rapid development and adoption have relied not only on an efficient stabilizing system (oil and surfactant), but also on a library of modules that can manipulate droplets at a high-throughput. Droplet microfluidics is a vibrant field that keeps evolving, with advances that span technology development and applications. Recent examples include innovative methods to generate droplets, to perform single-cell encapsulation, magnetic extraction, or sorting at an even higher throughput. The trend consists of improving parameters such as robustness, throughput, or ease of use. These developments rely on a firm understanding of the physics and chemistry involved in hydrodynamic flow at a small scale. Finally, droplet microfluidics has played a pivotal role in biological applications, such as single-cell genomics or high-throughput microbial screening, and chemical applications. This Special Issue will showcase all aspects of the exciting field of droplet microfluidics, including, but not limited to, technology development, applications, and open-source systems.
Author: Sebastian Seiffert Publisher: Walter de Gruyter GmbH & Co KG ISBN: 3110487845 Category : Technology & Engineering Languages : en Pages : 392
Book Description
Microfluidics introduces the theory and practice of fluid flow on small scales. The exquisite control of such flow at low Reynolds numbers allows liquids to be processed in either a well-defined co-flow or a well-defined segmented-flow fashion. Both lays a ground for high-throughput analytics and advanced materials design. With that, this book is ideal for research scientists and Ph.D. students in the fields of chemistry, chemical engineering, biotechnology, and materials science.
Author: Pengtao Yue Publisher: MDPI ISBN: 3039282964 Category : Technology & Engineering Languages : en Pages : 142
Book Description
The presence of drops, bubbles, and particles affects the behavior and response of complex multiphase fluids. In many applications, these complex fluids have more than one non-Newtonian component, e.g., polymer melts, liquid crystals, and blood plasma. In fact, most fluids exhibit non-Newtonian behaviors, such as yield stress, viscoelastity, viscoplasticity, shear thinning, or shear thickening, under certain flow conditions. Even in the complex fluids composed of Newtonian components, the coupling between different components and the evolution of internal boundaries often lead to a complex rheology. Thus the dynamics of drops, bubbles, and particles in both Newtonian fluids and non-Newtonian fluids are crucial to the understanding of the macroscopic behavior of complex fluids. This Special Issue aims to gather a wide variety of papers that focus on drop, bubble and particle dynamics in complex fluids. Potential topics include, but are not limited to, drop deformation, rising drops, pair-wise drop interactions, drop migration in channel flows, and the interaction of particles with flow systems such as pastes and slurries, glasses, suspensions, and emulsions. We emphasize numerical simulations, but also welcome experimental and theoretical contributions.
Author: Pooyan Tirandazi Publisher: ISBN: Category : Computational fluid dynamics Languages : en Pages : 151
Book Description
"Understanding the dynamics of fluids has enabled humans to devise strategies for a myriad of global challenges on a wide range of scales, from nanotechnology to space exploration. By designing and developing systems for manipulating fluid flows, researchers not only constantly optimize many of the conventional approaches to older engineering tasks, but also establish novel methods to tackle new and unsolved problems in science and technology. The advent of microfabrication and microfluidics along with improvements in numerical methodologies and computational power have equipped researchers with unprecedented resources to address these problems. In this work, I aim to investigate two areas where fluids engineering plays a critical role: droplet generation in microfluidic systems and fluid drag reduction of microtextured surfaces. In the first part, I study a relatively new area - droplet generation in microchannels using a high-speed gas phase flow. The use of microdroplets has become ubiquitous in many Lab-on-a-Chip applications ranging from material synthesis to biochemical sensing and testing. Droplet-microfluidics offers a promising approach for controlled generation and manipulation of uniform fluid entities. Despite the versatility and unparalleled control of the droplet formation and transport, the range of droplet microfluidic applications could be greatly expanded by enhancing the per-channel throughput and improving the interaction of droplets and jets with the continuous flow and the microchannel. I investigate a new class of droplet-based systems that uses a high-speed gaseous flow to generate uniform liquid droplets in a flow-focusing geometry. The interaction of the liquid and gas inside the microchannel creates distinct flow patterns. By characterizing the operation extent of resulting flow maps, I then focus on the Dripping and Jetting modes of droplet formation. To improve the performance of the droplet generation, I design and fabricate a three-dimensional microchannel architecture to facilitate formation of a contact-less liquid jet within the air flow inside the microchannel. Droplet generation frequency in this non-planar microchannel increase by at least one order of magnitude in comparison to conventional liquid-liquid droplet systems. The high-speed nature of the flows in this system, however, poses new challenges, namely inertial and compressibility effects on precise control of the jets and droplets. I use numerical simulations to further investigate the flow dynamics and determine the local pressure and velocity of the air inside the microchannel. The knowledge gained from this discussion of the fundamentals and physics is subsequently leveraged in applications that can benefit from this system. I propose a novel technique to use droplets as isolated micro-reactors for absorbing and detecting airborne targets and provide a proof-of-concept for sensing gaseous ammonia using sample digitization with microdroplets. In addition, I present the potential of using gas-liquid droplets as a template for polymer particle fabrication by showing experimental results that demonstrate the generation of calcium alginate microgels purely in air. At the end of this part, I discuss the current challenges in each application and suggest possible solutions towards effective implementation of this system for next generation microfluidic systems in particle synthesis and biochemical diagnostics. In the second part, I revisit a relatively old problem - understanding the dynamics of the laminar flow over textured surfaces for drag reduction applications. Inspired by the natural skins of certain plants and animals, introducing surface corrugations is a proven strategy to reduce the fluid drag and create a superhydrophobic effect, which has potential environmental and economic benefits. I examine the effects of periodic transverse grooves on the laminar boundary layer flow for mid- to high-Reynolds numbers (1000-25000). The width-to-depth aspect ratio of the grooves (AR) is a critical parameter that determines flow behavior near the grooves. Using finite element simulations, I study the local and temporal pressure and velocity fields in rectangular grooves for a wide range of aspect ratios (0.2
Author: Andreas Grimmer Publisher: Springer ISBN: 3030207137 Category : Technology & Engineering Languages : en Pages : 145
Book Description
This book describes automatic methods for the design of droplet microfluidic networks. The authors discuss simulation and design methods which support the design process of droplet microfluidics in general, as well as design methods for a dedicated droplet routing mechanism, namely passive droplet routing. The methods discussed allow for simulating a microfluidic design on a high-abstraction level, which facilitates early validation of whether a design works as intended, automatically dimensioning a microfluidic design, so that constraints like flow conditions are satisfied, and automatically generating meander designs for the respective needs and fabrication settings. Dedicated methods for passive droplet routing are discussed and allow for designing application-specific architectures for a given set of experiments, as well as generating droplet sequences realizing the respective experiments. Together, these methods provide a comprehensive “toolbox" for designers working on droplet microfluidic networks in general and an integrated design flow for the passive droplet routing mechanism in particular. Provides both a comprehensive “toolbox" for designers working on droplet microfluidic networks in general and an integrated design flow for the passive droplet routing mechanism in particular; Describes for the first time CAD methods for droplet microfluidic networks, along with the first integrated design process; Includes open source implementations, in order to reach the largest possible user group within the domain of microfluidics.
Author: Leon P. Berton Publisher: Nova Publishers ISBN: 9781600214868 Category : Technology & Engineering Languages : en Pages : 412
Book Description
Chemical engineering deals with the application of physical science (in particular chemistry and physics) and mathematics to the process of converting raw materials or chemicals into more useful or valuable forms. As well as producing useful materials, chemical engineering is also concerned with pioneering valuable new materials and techniques; an important form of research and development with direct applications in pharmaceuticals, semiconductors, artificial kidneys, oil refineries, solar panels, clean water, and biocompatible polymers! This book presents important research in this explosive field.
Author: Yong Ren Publisher: BoD – Books on Demand ISBN: 1789844185 Category : Technology & Engineering Languages : en Pages : 184
Book Description
Microfluidics have aroused a new surge of interest in recent years in environmental and energy areas, and inspired novel applications to tackle the worldwide challenges for sustainable development. This book aims to present readers with a valuable compendium of significant advances in applying the multidisciplinary microfluidic technologies to address energy and environmental problems in a plethora of areas such as environmental monitoring and detection, new nanofluid application in traditional mechanical manufacturing processes, development of novel biosensors, and thermal management. This book will provide a new perspective to the understanding of the ever-growing importance of microfluidics.