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Author: Ch Kunz Publisher: ISBN: Category : Languages : en Pages : 73
Book Description
In field studies 27 virus strains were isolated from ticks. A focus of TBE virus was found considerably further west than any other focus previously detected. Sera of small mammals showed a low incidence and sera of game showed a high incidence of antibodies to TBE virus. Virus strain could be rapidly identified with fluorescent antibodies. The innate resistance to TBE virus of Mus musculus spicilegus is probably due to a single dominant gene. The mouse brain lipid capable of inhibiting hemagglutination of TBE virus is most probably phosphatydilinositol-diphosphate. Its full action requires the presence of auxiliary lipids containing a trimethyl-ammonium group. Preliminary results indicate that the lipid can also inhibit the virus adsorption onto tissue culture cells. In sera from both the acute stage of TBE and from convalescence complement-fixing antibodies were predominantly found in the 7 S gamma globulin fraction. From 39 persons 38 still had complement-fixing and all had hemagglutination-inhibiting antibodies 6-9 years after overt TBE. Continuous propagation of a TBE virus strain led to overattenuation of the virus. In 1966, 136 TBE cases from Austria and 5 cases from Western Germany were diagnosed.
Author: Ch Kunz Publisher: ISBN: Category : Languages : en Pages : 73
Book Description
In field studies 27 virus strains were isolated from ticks. A focus of TBE virus was found considerably further west than any other focus previously detected. Sera of small mammals showed a low incidence and sera of game showed a high incidence of antibodies to TBE virus. Virus strain could be rapidly identified with fluorescent antibodies. The innate resistance to TBE virus of Mus musculus spicilegus is probably due to a single dominant gene. The mouse brain lipid capable of inhibiting hemagglutination of TBE virus is most probably phosphatydilinositol-diphosphate. Its full action requires the presence of auxiliary lipids containing a trimethyl-ammonium group. Preliminary results indicate that the lipid can also inhibit the virus adsorption onto tissue culture cells. In sera from both the acute stage of TBE and from convalescence complement-fixing antibodies were predominantly found in the 7 S gamma globulin fraction. From 39 persons 38 still had complement-fixing and all had hemagglutination-inhibiting antibodies 6-9 years after overt TBE. Continuous propagation of a TBE virus strain led to overattenuation of the virus. In 1966, 136 TBE cases from Austria and 5 cases from Western Germany were diagnosed.
Author: Ibrahim Abubakar Publisher: Oxford University Press ISBN: 0191030554 Category : Medical Languages : en Pages : 295
Book Description
Infectious Disease Epidemiology is a concise reference guide which provides trainees and practicing epidemiologists with the information that they need to understand the basic concepts necessary for working in this specialist area. Divided into two sections, part one comprehensively covers the basic principles and methods relevant to the study of infectious disease epidemiology. It is organised in order of increasing complexity, ranging from a general introduction to subjects such as mathematical modelling and sero-epidemiology. Part two examines key major infectious diseases that are of global significance. Grouped by their route of transmission for ease of reference, they include diseases that present a particular burden or a high potential for causing mortality. This practical guide will be essential reading for postgraduate students in infectious disease epidemiology, health protection trainees, and practicing epidemiologists.
Author: Didier Raoult Publisher: CRC Press ISBN: 142001997X Category : Medical Languages : en Pages : 400
Book Description
The only available reference to comprehensively discuss the common and unusual types of rickettsiosis in over twenty years, this book will offer the reader a full review on the bacteriology, transmission, and pathophysiology of these conditions. Written from experts in the field from Europe, USA, Africa, and Asia, specialists analyze specific patho
Author: Prof. Dr. Gerhard Dobler Publisher: Global Health Press ISBN: 9811409145 Category : Medical Languages : en Pages : 470
Book Description
While the number of vector-borne diseases and their incidence in Europe is much less than in tropical and/or developing countries, there are nevertheless a substantial number of such infections in Europe. The most important one is the zoonotic arbovirus infection Tick-Borne Encephalitis (TBE), a virus transmitted to humans by ticks or by consumption of unpasteurized dairy products from infected cows, goats, or sheep. TBE is endemic in the non-tropical Eurasian forest belt with most cases occurring in Russia and in central and eastern parts of Europe. In endemic areas, TBE is one of the most important causes of viral meningitis/encephalitis and a major public health concern. Moreover, TBE is becoming more and more frequent in Europe due to the appearance of new endemic areas and increasing awareness. However, it might be difficult to diagnose TBE, because clinical manifestations tend to be relatively nonspecific. Although a standardized case definition across the European Union has existed now for a few years, national implementation of TBE programs, including regular screening and diagnosis, are done in only very few countries. Therefore, wide differences in the intensity and quality of national surveillance of TBE cases still exist, and the true burden of disease and the areas with circulation of the TBE viral subtypes in Europe and Asia are not fully known. Moreover, although safe and effective vaccines are available, vaccination uptake in most endemic countries is too low to reduce the TBE burden significantly. The authors of “The TBE Book’ therefore have tried to compile in this “working book” the most recent and relevant aspects of TBE.
Author: Lisa A. Beltz Publisher: Elsevier Health Sciences ISBN: 0323825028 Category : Medical Languages : en Pages : 212
Book Description
Offering up-to-date coverage of familiar flaviviruses that are spreading into new regions or are causing increasingly severe disease, as well as viruses that are almost unknown in most developed nations, Zika and Other Neglected and Emerging Flaviviruses brings together information that allows for easy comparison of similarities and differences of this viral group in a single, convenient volume. Each chapter includes a brief Introduction, history, the diseases, the virus, the immune response, prevention or treatment, an extensive list of references, and a summary overview. The book concludes with a chapter tying together information about flaviviruses and other potential new microbial threats. Covers familiar flaviviruses that are spreading into new regions or are causing increasingly severe disease (such as Zika, dengue and West Nile viruses), as well as lesser-knowns viruses such as tick-borne encephalitis virus, Powassan virus, Omsk hemorrhagic fever, and Murray Valley encephalitis virus. Allows health-related personnel to search for potential treatments and protective responses by examining what measure did or did not work with other, related flaviviruses. Helps readers understand how to prevent or contain newly emerging viral threats—a particularly timely topic regarding the global spread of COVID-19 and the potential of tick-borne encephalitis to rapidly spread and cause severe illness, panic, and disruption of economies. Consolidates today’s available information on this timely topic into a single, convenient resource.
Author: Alan S. Bowman Publisher: Cambridge University Press ISBN: 1107321077 Category : Science Languages : en Pages : 1068
Book Description
Widespread and increasing resistance to most available acaracides threatens both global livestock industries and public health. This necessitates better understanding of ticks and the diseases they transmit in the development of new control strategies. Ticks: Biology, Disease and Control is written by an international collection of experts and covers in-depth information on aspects of the biology of the ticks themselves, various veterinary and medical tick-borne pathogens, and aspects of traditional and potential new control methods. A valuable resource for graduate students, academic researchers and professionals, the book covers the whole gamut of ticks and tick-borne diseases from microsatellites to satellite imagery and from exploiting tick saliva for therapeutic drugs to developing drugs to control tick populations. It encompasses the variety of interconnected fields impinging on the economically important and biologically fascinating phenomenon of ticks, the diseases they transmit and methods of their control.
Author: Ch Kunz
Author: Ch Kunz
Author: Pontus Lindblom
Author: Ibrahim Abubakar
Author: National Library of Medicine (U.S.)
Author: Didier Raoult
Author: Defense Documentation Center (U.S.)
Author: Prof. Dr. Gerhard Dobler
Author: National Library of Medicine (U.S.)
Author: Lisa A. Beltz
Author: Alan S. Bowman