Focus on Meningitis Research

Focus on Meningitis Research PDF Author: Phyllis V. Strong
Publisher: Nova Publishers
ISBN: 9781590339442
Category : Meningitis
Languages : en
Pages : 282

Book Description
Meningitis is an infection of the fluid of a person's spinal cord and the fluid that surrounds the brain. People sometimes refer to it as spinal meningitis. Meningitis is usually caused by a viral or bacterial infection. Knowing whether meningitis is caused by a virus or bacterium is important because the severity of illness and the treatment differ. Viral meningitis is generally less severe and resolves without specific treatment, while bacterial meningitis can be quite severe and may result in brain damage, hearing loss, or learning disability. For bacterial meningitis, it is also important to know which type of bacteria is causing the meningitis because antibiotics can prevent some types from spreading and infecting other people. Before the 1990s, Haemophilus influenzae type b (Hib) was the leading cause of bacterial meningitis, but new vaccines being given to all children as part of their routine immunizations have reduced the occurrence of invasive disease due to H. influenzae. Today, Streptococcus pneumoniae and Neisseria meningitides are the leading causes of bacterial meningitis.

Bacterial Meningitis—Advances in Research and Application: 2012 Edition

Bacterial Meningitis—Advances in Research and Application: 2012 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 1481638661
Category : Medical
Languages : en
Pages : 20

Book Description
Bacterial Meningitis—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Bacterial Meningitis in a compact format. The editors have built Bacterial Meningitis—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bacterial Meningitis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Bacterial Meningitis—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Management of Subarachnoid Hemorrhage

Management of Subarachnoid Hemorrhage PDF Author: Adel E. Ahmed Ganaw
Publisher: Springer Nature
ISBN: 3030813339
Category : Medical
Languages : en
Pages : 227

Book Description
This book focuses on subarachnoid hemorrhage (SAH), describing in detail the neurophysiology, anatomy, epidemiology, grading, anesthesia management, coiling and interventional treatment of this dangerous disease. Written by leading international experts, it highlights the state-of-the-art techniques for the diagnosis and treatment (non-surgical and surgical) of SAH and the clinical variations. It also examines the reliability of the new techniques versus the standard clinical methods to predict problems related to SAH and its recent diagnosis and management. The book starts with a brief discussion of the epidemiology of SAH, cerebral circulation, anatomy of brain blood vessels and neurophysiology related to this fatal disease. Then, in the following chapters it covers grading of subarachnoid hemorrhage, anesthesia management of SAH, treatment, subarachnoid hemorrhage coiling and radiological intervention. Lastly, it explores surgical treatment of intracranial aneurysms in more detail, and addresses complications, critical care management and headache in SAH, traumatic SAH and prognosis. Featuring numerous images, tables, schema, illustrations and videos, the book is intended for junior and senior anesthesiologists, neuroscientists, intervention radiologists, intensivists and neurosurgeons.

Bacterial Infections of the Central Nervous System

Bacterial Infections of the Central Nervous System PDF Author: Karen L. Roos
Publisher: Elsevier Health Sciences
ISBN: 0444520155
Category : Medical
Languages : en
Pages : 293

Book Description
Bacterial Infections of the Central Nervous System aims to provide information useful to physicians taking care of patients with bacterial infections in the central nervous system (CNS), which can lead to morbidity and mortality. The increased number of patients suffering from this infection has led to the development of vaccines and antibiotics. Comprised of four chapters, the book explains the general approach to patients with bacterial CNS infection. It also discusses various CNS infection concepts and terms. These include the characteristic neuroimaging appearance of specific bacterial infections, the limitations of neuroimaging, the cerebrospinal fluid analysis, the pathogenesis and pathophysiology of bacterial CNS infections, the developments of specific adjunctive strategies, and the principles of antimicrobial therapy. It also includes discussions on various diseases that target the CNS, such as meningitis, focal CNS infections, neurological complications of endocarditis, suppurative venous sinus thrombosis, infections in the neurosurgical patient, and CNS diseases caused by selected infectious agents and toxins. This book will serve as a guide for clinical physicians who have patients suffering from bacterial CNS infection.

Handbook of Meningococcal Disease

Handbook of Meningococcal Disease PDF Author: Matthias Frosch
Publisher: John Wiley & Sons
ISBN: 3527614451
Category : Medical
Languages : en
Pages : 592

Book Description
A comprehensive overview of recent advances, from current basic research and epidemiology, to novel therapeutic strategies and clinical management. Here, the leading scientists who have made major advances in the field provide up-to-date reviews and describe their current knowledge and concepts. As such, this is the first volume to summarize the implications of the meningococcus genome-sequencing project, emphasizing the novel strategies in vaccine development. Following a look at the history, the authors go on to treat the epidemiology of meningococcal disease, as well as the genetics, structure and function of virulence factors. Further chapters cover cross-talk between meningococci and host cells, genomics and immunobiology. The result is a standard handbook for all scientists working in the field. While aimed at advanced specialists in basic research, epidemiologists, public health workers, vaccine developers and clinicians, the book is equally appropriate as introductory reading for graduates embarking on their career in this field.

Bacterial Meningitis

Bacterial Meningitis PDF Author: Diana E. Lang
Publisher: Nova Science Publishers
ISBN: 9781634632256
Category : Allergy
Languages : en
Pages : 0

Book Description
Despite advances in medical care, improvement of anti-microbial and anti-inflammatory therapy and worldwide immunisation programs, bacterial meningitis is still responsible for substantial morbidity and mortality in both developed and developing countries. A worldwide reported mortality rate from bacterial meningitis continue to be high, ranging between 2% to 30%. Twenty percent of survivors develop neurological sequelae. During the last decades, the disease epidemiology has changed dramatically in the countries that implemented the conjugate vaccines against the most common meningeal pathogens. Also in developing countries, gradual changes have been observed in the epidemiology of bacterial meningitis that are unrelated to the introduction of new vaccines, but are partly due to the improvement of living conditions. This book examines the modes of transmission of bacterial meningitis, as well as the clinical characteristics, and treatment options.

Tuberculosis of the Central Nervous System

Tuberculosis of the Central Nervous System PDF Author: Mehmet Turgut
Publisher: Springer
ISBN: 3319507125
Category : Medical
Languages : en
Pages : 615

Book Description
Written and edited by leading international authorities in the field, this book provides an in-depth review of knowledge of tuberculosis of the central nervous system, with emphasis on clinical, diagnostics, and therapeutic features. Tuberculosis, one of the most lethal diseases in human history, still poses a serious threat in the world together with economic and social problems, although a great progress in the fight against this infectious disease in the last century. It covers the full range of tuberculosis of central nervous system and the chapters are organized into six sections: (1) the cranial; (2) the spinal; and (3) the peripheral portions of the nervous system; followed by (4) a section on the laboratory studies in tuberculosis; (5) a section on medical and surgical therapy; and (6) further insights into tuberculosis. This comprehensive reference book will be an ideal source for neurosurgeons, neurologists and specialists upon infectious diseases seeking both basic and more sophisticated information and surgical procedures relating to the complications associated with tuberculosis involving the spine, brain and peripheral nerves.

Meningitis and Encephalitis

Meningitis and Encephalitis PDF Author: Rodrigo Hasbun
Publisher: Springer
ISBN: 3319926780
Category : Medical
Languages : en
Pages : 238

Book Description
Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae. The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs, overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportion of unknown etiologies, low sensitivity of current microbiological techniques especially in the setting of previous antibiotic therapy, underutilization of available molecular diagnostic tests, and empiric antibiotic therapy and hospitalization for viral meningitis cases. Even though there are published guidelines, compliance with them is not optimal and physicians do not follow standardized algorithms in their empirical approach. As meningitis and encephalitis is associated with high rates of adverse clinical outcomes, prevention, when feasible is of upmost importance. Adherence to protocols to prevent health-care associated meningitis and ventriculitis are effective but compliance with them is not uniformly performed. This book seeks to improve outcomes for meningitis and encephalitis cases handled by physicians who may or may not be thoroughly trained for these challenges. The text introduces the current guidelines but also discusses the gaps that leave clinicians struggling to implement the most appropriate approaches for these particular neurological infections. Each chapter delivers the tools necessary to identify and adhere to the most appropriate diagnostic technique, management protocols, and prevention approach for each situation. All chapters conclude with discourse on future directions in research and quality improvement. Written by experts in infectious diseases, the book covers topics that are the most devastating, including healthcare-acquired infections, autoimmune encephalitis, and infections as they present in HIV patients. Meningitis and Encephalitis is a well-rounded resource for all medical professionals encountering these neurological syndromes, including infectious disease specialists, neurologists, primary care physicians, and immunologists.

Continual Raving

Continual Raving PDF Author: Janet R. Gilsdorf
Publisher: Oxford University Press
ISBN: 0190677333
Category : Medical
Languages : en
Pages : 256

Book Description
Not all scientific discoveries are genius. Continual Raving tells the combined stories of how scientists across the 19th and 20th centuries defeated meningitis -- not through flawless scientific research, but often through a series of serendipitous events, misplaced assumptions, and flawed conclusions. The result is a story of not just a vanquished disease, but how scientific accomplishment sometimes occurs where it's least expected. Although symptoms of meningitis were recorded as early as Hippocrates and the ancient Greeks, our understanding of the disease's origins and mechanisms remained obscure for most of human history. That changed in 1892, when German physician Richard Pfeiffer observed and isolated bacteria ultimately shown to cause meningitis in children -- and concluded that those bacteria cause influenza. Haemophilus influenzae, as thee meningitis-causing bacteria have been erroneously named ever since, continued their strange journey to discovery in the decades that followed. Continual Raving traces the disease's strange encounters with science, including: · Heinrich Quincke, the German internist who first used a needle to draw spinal fluid from between a patient's back bones · Simon Flexner's management of American meningitis epidemics using immune serum from a horse · American bacteriologist Margaret Pittman's discovery (during the Great Depression, no less) of a sugar overcoat that protects the bacteria from white blood cells · Pediatrician Ashley Weech, who gave the first antibiotic used in America (based on instructions written in German) to a young patient sick with meningitis · Microbiologist Hattie Alexander, who learned why these antibiotics sometimes fail in such patients · Four scientists, in two teams, as they vied to be the first to create the right vaccine to prevent meningitis in infants In each of these deeply human stories, variables of chance, circumstance, and incorrect assumptions intervene to shape not just the arc of the scientists' lives, but the trajectory of how humans have come to understand one of our most pernicious diseases. Continual Raving is a mosaic tale of how science conquered meningitis -- and a larger story of the sometimes winding road to discovery.

Meningitis

Meningitis PDF Author: Anthony L. Shrader
Publisher: Nova Science Publishers
ISBN: 9781631171369
Category : Meningitis
Languages : en
Pages : 0

Book Description
In this book the authors present current research in the study of meningitis. Topics discussed in this compilation include the drug induced aseptic meningitis; bacterial meningitis; the role of prophylactic antibiotics in posttraumatic meningitis; meningitis associated with auto-immune diseases; sepsis and bacteremia, meningitis, influenza infection, and infectious diarrhoea.