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Author: Organizer Committee IPAP18 – Salamanca Publisher: Ediciones Universidad de Salamanca ISBN: 8490129762 Category : Medical Languages : es Pages : 358
Book Description
This book contains the summaries of the "Innovation in Pharmacy: Advances and Perspectives" that took place in Salamanca (Spain) in September 2018. The early science of chemistry and microbiology were the source of most drugs until the revolution of genetic engineering in the mid 1970s. Then biotechnology made available novel protein agents such as interferons, blood factors and monoclonal antibodies that have changed the modern pharmacy. Over the past year, a new pharmacy of oligonucleotides has emerged from the science of gene expression such as RNA splicing and RNA interference. The ability to design therapeutic agents from genomic sequences will transform treatment for many diseases. The science that created this advance and its future promise will be discussed. Phillip Allen Sharp is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for “the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence. He works in Institute Professor Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, US. Este libro recoge los resúmenes de la «Innovation in Pharmacy: Advances and Perspectives» que tuvo lugar en Salamanca (España) en septiembre de 2018. La ciencia primitiva de la química y la microbiología fue la fuente de la mayoría de las drogas hasta la revolución de la ingeniería genética a mediados de la década de 1970. Luego, la biotecnología puso a disposición agentes proteínicos novedosos como interferones, factores sanguíneos y anticuerpos monoclonales que han cambiado la farmacia moderna. Durante el año pasado, surgió una nueva farmacia de oligonucleótidos a partir de la ciencia de la expresión génica, como el empalme de ARN y la interferencia de ARN. La capacidad de diseñar agentes terapéuticos a partir de secuencias genómicas transformará el tratamiento de muchas enfermedades. La ciencia que creó este avance y su promesa futura será discutida. Phillip Allen Sharp es un genetista y biólogo molecular estadounidense que co-descubrió el empalme de ARN. Compartió el Premio Nobel de 1993 en Fisiología o Medicina con Richard J. Roberts por "el descubrimiento de que los genes en eucariotas no son cadenas contiguas, sino que contienen intrones, y que el empalme del ARN mensajero para eliminar esos intrones puede ocurrir de diferentes maneras, produciendo diferentes proteínas de la misma secuencia de ADN. Trabaja en el Instituto Profesor Koch Institute for Integrative Cancer Research, Instituto Tecnológico de Massachusetts (MIT), Cambridge, MA, EE. UU.
Author: Organizer Committee IPAP18 – Salamanca Publisher: Ediciones Universidad de Salamanca ISBN: 8490129762 Category : Medical Languages : es Pages : 358
Book Description
This book contains the summaries of the "Innovation in Pharmacy: Advances and Perspectives" that took place in Salamanca (Spain) in September 2018. The early science of chemistry and microbiology were the source of most drugs until the revolution of genetic engineering in the mid 1970s. Then biotechnology made available novel protein agents such as interferons, blood factors and monoclonal antibodies that have changed the modern pharmacy. Over the past year, a new pharmacy of oligonucleotides has emerged from the science of gene expression such as RNA splicing and RNA interference. The ability to design therapeutic agents from genomic sequences will transform treatment for many diseases. The science that created this advance and its future promise will be discussed. Phillip Allen Sharp is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for “the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence. He works in Institute Professor Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, US. Este libro recoge los resúmenes de la «Innovation in Pharmacy: Advances and Perspectives» que tuvo lugar en Salamanca (España) en septiembre de 2018. La ciencia primitiva de la química y la microbiología fue la fuente de la mayoría de las drogas hasta la revolución de la ingeniería genética a mediados de la década de 1970. Luego, la biotecnología puso a disposición agentes proteínicos novedosos como interferones, factores sanguíneos y anticuerpos monoclonales que han cambiado la farmacia moderna. Durante el año pasado, surgió una nueva farmacia de oligonucleótidos a partir de la ciencia de la expresión génica, como el empalme de ARN y la interferencia de ARN. La capacidad de diseñar agentes terapéuticos a partir de secuencias genómicas transformará el tratamiento de muchas enfermedades. La ciencia que creó este avance y su promesa futura será discutida. Phillip Allen Sharp es un genetista y biólogo molecular estadounidense que co-descubrió el empalme de ARN. Compartió el Premio Nobel de 1993 en Fisiología o Medicina con Richard J. Roberts por "el descubrimiento de que los genes en eucariotas no son cadenas contiguas, sino que contienen intrones, y que el empalme del ARN mensajero para eliminar esos intrones puede ocurrir de diferentes maneras, produciendo diferentes proteínas de la misma secuencia de ADN. Trabaja en el Instituto Profesor Koch Institute for Integrative Cancer Research, Instituto Tecnológico de Massachusetts (MIT), Cambridge, MA, EE. UU.
Author: Joachim Gottsmann Publisher: Springer ISBN: 331958412X Category : Nature Languages : en Pages : 313
Book Description
This open access book summarizes the findings of the VUELCO project, a multi-disciplinary and cross-boundary research funded by the European Commission's 7th framework program. It comprises four broad topics: 1. The global significance of volcanic unrest 2. Geophysical and geochemical fingerprints of unrest and precursory activity 3. Magma dynamics leading to unrest phenomena 4. Bridging the gap between science and decision-making Volcanic unrest is a complex multi-hazard phenomenon. The fact that unrest may, or may not lead to an imminent eruption contributes significant uncertainty to short-term volcanic hazard and risk assessment. Although it is reasonable to assume that all eruptions are associated with precursory activity of some sort, the understanding of the causative links between subsurface processes, resulting unrest signals and imminent eruption is incomplete. When a volcano evolves from dormancy into a phase of unrest, important scientific, political and social questions need to be addressed. This book is aimed at graduate students, researchers of volcanic phenomena, professionals in volcanic hazard and risk assessment, observatory personnel, as well as emergency managers who wish to learn about the complex nature of volcanic unrest and how to utilize new findings to deal with unrest phenomena at scientific and emergency managing levels. This book is open access under a CC BY license.
Author: Masanori Kaji Publisher: Oxford University Press, USA ISBN: 0190200073 Category : Law Languages : en Pages : 345
Book Description
A collection of comparative studies on the reception, response, and appropriation of the periodic system of elements in eleven countries.
Author: Martina Gerken Publisher: Göttingen University Press ISBN: 3863954084 Category : Agriculture (General) Languages : en Pages : 374
Book Description
Animal fibres from South American camelids and other fibre or wool bearing species provide important products for use by the human population. The contemporary context includes the competition with petrocarbon-based artificial fibres and concern about excessive persistence of these in the natural environment. Animal fibres present highly valuable characteristics for sustainable production and processing as they are both natural and renewable. On the other hand, their use is recognised to depend on availability of appropriate quality and quantity, the production of which is underpinned by a range of sciences and processes which support development to meet market requirements. This collection of papers combines international experience from South and North America, China and Europe. The focus lies on domestic South American camelids (alpacas, llamas) and also includes research on sheep and goats. It considers latest advances in sustainable development under climate change, breeding and genetics, reproduction and pathology, nutrition, meat and fibre production and fibre metrology. Publication of this book is supported by the Animal Fibre Working Group of the European Federation of Animal Science (EAAP). ‘Advances in Fibre Production Science in South American Camelids and other Fibre Animals’ addresses issues of importance to scientists and animal breeders, textile processors and manufacturers, specialised governmental policy makers and students studying veterinary, animal and applied biological sciences.
Author: Dina Prialnik Publisher: Elsevier ISBN: 0128175257 Category : Science Languages : en Pages : 480
Book Description
The Trans-Neptunian Solar System is a timely reference highlighting the state-of-the-art in current knowledge on the outer solar system. It not only explores the individual objects being discovered there, but also their relationships with other Solar System objects and their roles in the formation and evolution of the Solar System and other planets. Integrating important findings from recent missions, such as New Horizons and Rosetta, the book covers the physical properties of the bodies in the Trans-Neptunian Region, including Pluto and other large members of the Kuiper Belt, as well as dynamical indicators for Planet 9 and related objects and future prospects. Offering a complete look at exploration and findings in the Kuiper Belt and the rest of the outer solar system beyond Neptune, this book is an important resource to bring planetary scientists, space scientists and astrophysicists up-to-date on the latest research and current understandings. - Provides the most up-to-date information on the exploration of the Trans-Neptunian Solar System and what it means for the future of outer solar system research - Contains clear sections that provide comprehensive coverage on the most important facets of the outer Solar System - Includes four-color images and data from important missions, including New Horizons and Rosetta - Concludes with suggestions and insights on the future of research on Trans-Neptunian objects
Author: Piet Lens Publisher: IWA Publishing ISBN: 1843391007 Category : Science Languages : en Pages : 545
Book Description
Soil and Sediment Remediation discusses in detail a whole set of remediative technologies currently available to minimise their impact. Technologies for the treatment of soils and sediments in-situ (landfarming, bioscreens, bioventing, nutrient injection, phytoremediation) and ex-situ (landfarming, bio-heap treatment, soil suspension reactor) will be discussed. The microbiological, process technological and socio-economical aspects of these technologies will be addressed. Special attention will be given to novel biotechnological processes that utilise sulfur cycle conversions, e.g. sulfur and heavy metal removal from soils. Also the potential of phytoremediation will be highlighted. In addition, treatment schemes for the clean-up of polluted megasites, e.g. harbours and Manufactured Gaswork Plants (MGP), will be elaborated. The aim of Soil and Sediment Remediation is to introduce the reader in: the biogeochemical characteristics of soil and sediments- new techniques to study soil/sediment processes (molecular probes, microelectrodes, NMR) clean up technologies for soils polluted with organic (PAH, NAPL, solvents) or inorganic (heavy metals) pollutants- preventative and remediative strategies and technologies available in environmental engineering novel process applications and bioreactor designs for bioremediation the impact of soil pollution on society and its economic importance.
Author: Publisher: ISBN: Category : Languages : en Pages : 0
Book Description
This book is devoted to an increasingly important educational problem in the modern societies: school achievement and failure. School failure is presently a problem in developed as well as in developing countries. In the Spanish and Portuguese speaking countries in Europe and Latin America, school achievement and failure is consequently an important topic of political, social and scientific discussion. The following papers revise the latest research in the field, from the perspective of Psychology.
Author: Jorge Garza Ulloa Publisher: Academic Press ISBN: 0128125950 Category : Technology & Engineering Languages : en Pages : 664
Book Description
Applied Biomechatronics Using Mathematical Models provides an appropriate methodology to detect and measure diseases and injuries relating to human kinematics and kinetics. It features mathematical models that, when applied to engineering principles and techniques in the medical field, can be used in assistive devices that work with bodily signals. The use of data in the kinematics and kinetics analysis of the human body, including musculoskeletal kinetics and joints and their relationship to the central nervous system (CNS) is covered, helping users understand how the complex network of symbiotic systems in the skeletal and muscular system work together to allow movement controlled by the CNS. With the use of appropriate electronic sensors at specific areas connected to bio-instruments, we can obtain enough information to create a mathematical model for assistive devices by analyzing the kinematics and kinetics of the human body. The mathematical models developed in this book can provide more effective devices for use in aiding and improving the function of the body in relation to a variety of injuries and diseases. - Focuses on the mathematical modeling of human kinematics and kinetics - Teaches users how to obtain faster results with these mathematical models - Includes a companion website with additional content that presents MATLAB examples
Author: Organizer Committee IPAP18 – Salamanca
Author: Organizer Committee IPAP18 – Salamanca
Author: Joachim Gottsmann
Author: Santiago Ramón y Cajal
Author: Masanori Kaji
Author: Martina Gerken
Author: Jane Haldimand Marcet
Author: Dina Prialnik
Author: Piet Lens
Author: 
Author: Jorge Garza Ulloa