Author: Sinuhe HahnPublisher:
ISBN:
Category :
Languages : en
Pages : 78
Book Description
Fetal Cells and Fetal Nucleic Acids in Maternal Blood
Author: Sinuhe HahnFetal Cells and Fetal DNA in Maternal Blood
Author: Sinuhe HahnPublisher: Karger Medical and Scientific Publishers
ISBN: 3805572220
Category : Medical
Languages : en
Pages : 145
Book Description
Is noninvasive, risk-free prenatal diagnosis of fetal genetic characteristics still a fantasy, or will it soon become reality? The current status of both the leading European research groups as well as the NIH-funded NIFTY study are reported here, indicating that certain fetal genetic traits can now be examined efficiently in a noninvasive manner. Considerable focus is placed on new laser-mediated systems for the effective micro-manipulation of single fetal cells, as well as their analysis by single-cell PCR and the pitfalls to avoid when performing such analyses. Other issues addressed in depth include: novel enrichment techniques, optimal fetal cell recognition, fetal cell culture, as well as the exciting finding that fetal cell traffic is elevated in certain pregnancy-related disorders, most prominently in preeclampsia. This publication is of interest to researchers in the field, genetic counsellors, gynecologists and obstetricians, and researchers in microchimerism, transplantation and transfusion medicine.
Fetal Cells and Fetal DNA in Maternal Blood
Author: S. HahnPublisher:
ISBN: 9783318006995
Category : Medical
Languages : en
Pages : 0
Book Description
Is noninvasive, risk-free prenatal diagnosis of fetal genetic characteristics still a fantasy, or will it soon become reality? The current status of both the leading European research groups as well as the NIH-funded NIFTY study are reported here, indicating that certain fetal genetic traits can now be examined efficiently in a noninvasive manner. Considerable focus is placed on new laser-mediated systems for the effective micro-manipulation of single fetal cells, as well as their analysis by single-cell PCR and the pitfalls to avoid when performing such analyses. Other issues addressed in depth include: novel enrichment techniques, optimal fetal cell recognition, fetal cell culture, as well as the exciting finding that fetal cell traffic is elevated in certain pregnancy-related disorders, most prominently in preeclampsia. This publication is of interest to researchers in the field, genetic counsellors, gynecologists and obstetricians, and researchers in microchimerism, transplantation and transfusion medicine.
Fetal Cells in Maternal Blood
Author: Joe Leigh SimpsonPublisher:
ISBN:
Category : Health & Fitness
Languages : en
Pages : 296
Book Description
Several lines of evidence indicate that foetal cells - lymphocytes, nucleated red cells, trophoblasts - exist in maternal blood during pregnancy. The potential thus exists for recovering foetal cells from maternal blood and then analysing these cells for foetal genetic abnormalities. This volume explores the biology and maternal foetal transfer of the three cell types during pregnancy, the use of flow cytometry and other techniques to enrich the yield of these cells from maternal blood, the application of diagnostic techniques for identifying cytogenetic and other genetic abnormalities, and public health and other issues involved in the implementation of such testing.
Circulating Nucleic Acids in Early Diagnosis, Prognosis and Treatment Monitoring
Author: Peter B. GahanPublisher: Springer
ISBN: 9401791686
Category : Medical
Languages : en
Pages : 476
Book Description
DNA and RNA fractions can be isolated from a variety of body fluids including whole blood, serum, plasma, urine, saliva and cerebrospinal fluid from both patients and healthy individuals. Such isolates can be exploited in the early detection of clinical disorders, stratification of patients for treatment, treatment monitoring and clinical follow-up. In addition, the use in fetal medicine allows the early detection of fetal sex, Rh factor and aneuploid disorders as well as following both fetal and premature born infant development. This volume is intended as a primer for those who are interested in entering the field of circulating nucleic acids. The areas covered in this volume include: · Background and general biology of circulating nucleic acids · Methodology · Applications of circulating nucleic acids · Quality Assurance · Ethics
Clinical Maternal-Fetal Medicine
Author: Hung N. WinnPublisher: CRC Press
ISBN: 1000533735
Category : Medical
Languages : en
Pages : 855
Book Description
This is a comprehensive, one-stop online book relating to all areas of pregnancy and birth. The second edition of this easily searchable guide is edited by eminent experts in the field and includes new contributions from international authors. It will be an ideal reference for Maternal-Fetal Specialists and Generalists wanting an authoritative answer on any point. Key features: •Grouped in to six topics (modules) for convenience •Electronic search facility across all chapters •Approximately 700,000 words of text, 7000 references, 300 figures (including 100 in full colour), and 200 tables available to search Key topics: •All common pregnancy and birth related problems such as diabetes and pregnancy •Many rarer complications such as protozoan infections •Fetal assessment, which is absolutely central to MFM practice •Medico-legal aspects •Sickle cell disease – a major problem for patients of African descent New chapters include: •Recurrent early pregnancy losses •Invasive hemodynamic monitoring •Chronic and acute hypertension •Neurological disorders •Maternal obesity •Assessment of fetal genetic disorders •First and second trimester screening
Genetic Analysis of Fetal Cells in Maternal Blood
Author: Yuk-Ming Dennis LoPublisher:
ISBN:
Category : Fetal cells from maternal blood
Languages : en
Pages : 0
Book Description
Variation in the Amount of Fetal Cells and Cell-free Fetal DNA in Maternal Blood
Author: Jacob Mørup SchlütterGenetic Analysis of Fetal Cells in Maternal Blood
Author: Yuk-Ming Dennis LoPublisher:
ISBN:
Category : Fetal cells from maternal blood
Languages : en
Pages : 316
Book Description
Author: Shruti Bajaj