Feature Selection and Ensemble Methods for Bioinformatics PDF Download

Author: Oleg Okun
Publisher:
ISBN:
Category :
Languages : en
Pages :

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"This book offers a unique perspective on machine learning aspects of microarray gene expression based cancer classification, combining computer science, and biology"--Provided by publisher.

Author: Oleg Okun
Publisher: IGI Global
ISBN: 9781609605575
Category : Computers
Languages : en
Pages : 0

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"This book offers a unique perspective on machine learning aspects of microarray gene expression based cancer classification, combining computer science, and biology"--Provided by publisher.

Author: Walter Daelemans
Publisher: Springer Science & Business Media
ISBN: 354087478X
Category : Computers
Languages : en
Pages : 714

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Book Description
This book constitutes the refereed proceedings of the joint conference on Machine Learning and Knowledge Discovery in Databases: ECML PKDD 2008, held in Antwerp, Belgium, in September 2008. The 100 papers presented in two volumes, together with 5 invited talks, were carefully reviewed and selected from 521 submissions. In addition to the regular papers the volume contains 14 abstracts of papers appearing in full version in the Machine Learning Journal and the Knowledge Discovery and Databases Journal of Springer. The conference intends to provide an international forum for the discussion of the latest high quality research results in all areas related to machine learning and knowledge discovery in databases. The topics addressed are application of machine learning and data mining methods to real-world problems, particularly exploratory research that describes novel learning and mining tasks and applications requiring non-standard techniques.

Author: Huan Liu
Publisher: CRC Press
ISBN: 1584888792
Category : Business & Economics
Languages : en
Pages : 437

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Book Description
Due to increasing demands for dimensionality reduction, research on feature selection has deeply and widely expanded into many fields, including computational statistics, pattern recognition, machine learning, data mining, and knowledge discovery. Highlighting current research issues, Computational Methods of Feature Selection introduces the

Author: Petra Perner
Publisher: Springer Science & Business Media
ISBN: 3642143997
Category : Computers
Languages : en
Pages : 667

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Book Description
These are the proceedings of the tenth event of the Industrial Conference on Data Mining ICDM held in Berlin (www.data-mining-forum.de). For this edition the Program Committee received 175 submissions. After the pe- review process, we accepted 49 high-quality papers for oral presentation that are included in this book. The topics range from theoretical aspects of data mining to app- cations of data mining such as on multimedia data, in marketing, finance and telec- munication, in medicine and agriculture, and in process control, industry and society. Extended versions of selected papers will appear in the international journal Trans- tions on Machine Learning and Data Mining (www.ibai-publishing.org/journal/mldm). Ten papers were selected for poster presentations and are published in the ICDM Poster Proceeding Volume by ibai-publishing (www.ibai-publishing.org). In conjunction with ICDM four workshops were held on special hot applicati- oriented topics in data mining: Data Mining in Marketing DMM, Data Mining in LifeScience DMLS, the Workshop on Case-Based Reasoning for Multimedia Data CBR-MD, and the Workshop on Data Mining in Agriculture DMA. The Workshop on Data Mining in Agriculture ran for the first time this year. All workshop papers will be published in the workshop proceedings by ibai-publishing (www.ibai-publishing.org). Selected papers of CBR-MD will be published in a special issue of the international journal Transactions on Case-Based Reasoning (www.ibai-publishing.org/journal/cbr).

Author: Alireza Fazelpour
Publisher:
ISBN:
Category : Artificial intelligence
Languages : en
Pages : 162

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Book Description
Developments in advanced technologies, such as DNA microarrays, have generated tremendous amounts of data available to researchers in the field of bioinformatics. These state-of-the-art technologies present not only unprecedented opportunities to study biological phenomena of interest, but signicant challenges in terms of processing the data. Furthermore, these datasets inherently exhibit a number of challenging characteristics, such as class imbalance, high dimensionality, small dataset size, noisy data, and complexity of data in terms of hard to distinguish decision boundaries between classes within the data. In recognition of the aforementioned challenges, this dissertation utilizes a variety of machine-learning and data-mining techniques, such as ensemble classification algorithms in conjunction with data sampling and feature selection techniques to alleviate these problems, while improving the classification results of models built on these datasets. However, in building classification models researchers and practitioners encounter the challenge that there is not a single classifier that performs relatively well in all cases. Thus, numerous classification approaches, such as ensemble learning methods, have been developed to address this problem successfully in a majority of circumstances. Ensemble learning is a promising technique that generates multiple classification models and then combines their decisions into a single final result. Ensemble learning often performs better than single-base classifiers in performing classification tasks. This dissertation conducts thorough empirical research by implementing a series of case studies to evaluate how ensemble learning techniques can be utilized to enhance overall classification performance, as well as improve the generalization ability of ensemble models. This dissertation investigates ensemble learning techniques of the boosting, bagging, and random forest algorithms, and proposes a number of modifications to the existing ensemble techniques in order to improve further the classification results. This dissertation examines the effectiveness of ensemble learning techniques on accounting for challenging characteristics of class imbalance and difficult-to-learn class decision boundaries. Next, it looks into ensemble methods that are relatively tolerant to class noise, and not only can account for the problem of class noise, but improves classification performance. This dissertation also examines the joint effects of data sampling along with ensemble techniques on whether sampling techniques can further improve classification performance of built ensemble models.

Author: Petra Perner
Publisher: Springer Science & Business Media
ISBN: 364203070X
Category : Computers
Languages : en
Pages : 837

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Book Description
There is no royal road to science, and only those who do not dread the fatiguing climb of its steep paths have a chance of gaining its luminous summits. Karl Marx A Universial Genius of the 19th Century Many scientists from all over the world during the past two years since the MLDM 2007 have come along on the stony way to the sunny summit of science and have worked hard on new ideas and applications in the area of data mining in pattern r- ognition. Our thanks go to all those who took part in this year's MLDM. We appre- ate their submissions and the ideas shared with the Program Committee. We received over 205 submissions from all over the world to the International Conference on - chine Learning and Data Mining, MLDM 2009. The Program Committee carefully selected the best papers for this year’s program and gave detailed comments on each submitted paper. There were 63 papers selected for oral presentation and 17 papers for poster presentation. The topics range from theoretical topics for classification, clustering, association rule and pattern mining to specific data-mining methods for the different multimedia data types such as image mining, text mining, video mining and Web mining. Among these topics this year were special contributions to subtopics such as attribute discre- zation and data preparation, novelty and outlier detection, and distances and simila- ties.

Author: Yanqing Zhang
Publisher: John Wiley & Sons
ISBN: 0470397411
Category : Computers
Languages : en
Pages : 476

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Book Description
An introduction to machine learning methods and their applications to problems in bioinformatics Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. From an internationally recognized panel of prominent researchers in the field, Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics. Coverage includes: feature selection for genomic and proteomic data mining; comparing variable selection methods in gene selection and classification of microarray data; fuzzy gene mining; sequence-based prediction of residue-level properties in proteins; probabilistic methods for long-range features in biosequences; and much more. Machine Learning in Bioinformatics is an indispensable resource for computer scientists, engineers, biologists, mathematicians, researchers, clinicians, physicians, and medical informaticists. It is also a valuable reference text for computer science, engineering, and biology courses at the upper undergraduate and graduate levels.

Author: Marco Loog
Publisher: Springer
ISBN: 3642248551
Category : Computers
Languages : en
Pages : 356

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Book Description
This book constitutes the refereed proceedings of the 6th International Conference on Pattern Recognition in Bioinformatics, PRIB 2011, held in Delft, The Netherlands, in November 2011. The 29 revised full papers presented were carefully reviewed and selected from 35 submissions. The papers cover the wide range of possible applications of bioinformatics in pattern recognition: novel algorithms to handle traditional pattern recognition problems such as (bi)clustering, classification and feature selection; applications of (novel) pattern recognition techniques to infer and analyze biological networks and studies on specific problems such as biological image analysis and the relation between sequence and structure. They are organized in the following topical sections: clustering, biomarker selection and classification, network inference and analysis, image analysis, and sequence, structure, and interactions.

Author: Verónica Bolón-Canedo
Publisher: Springer
ISBN: 3319900803
Category : Technology & Engineering
Languages : en
Pages : 212

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Book Description
This book offers a comprehensive overview of ensemble learning in the field of feature selection (FS), which consists of combining the output of multiple methods to obtain better results than any single method. It reviews various techniques for combining partial results, measuring diversity and evaluating ensemble performance. With the advent of Big Data, feature selection (FS) has become more necessary than ever to achieve dimensionality reduction. With so many methods available, it is difficult to choose the most appropriate one for a given setting, thus making the ensemble paradigm an interesting alternative. The authors first focus on the foundations of ensemble learning and classical approaches, before diving into the specific aspects of ensembles for FS, such as combining partial results, measuring diversity and evaluating ensemble performance. Lastly, the book shows examples of successful applications of ensembles for FS and introduces the new challenges that researchers now face. As such, the book offers a valuable guide for all practitioners, researchers and graduate students in the areas of machine learning and data mining.