Exploring Data in Engineering, the Sciences, and Medicine PDF Download

Author: Ronald Pearson
Publisher: Oxford University Press
ISBN:
Category : Mathematics
Languages : en
Pages : 794

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Book Description
This book introduces various widely available exploratory data analysis methods, emphasizing those that are most useful in the preliminary exploration of large datasets involving mixed data types. Topics include descriptive statistics, graphical analysis tools, regression modeling and spectrum estimation, along with practical issues like outliers, missing data, and variable selection.

Author: Ronald K. Pearson
Publisher: CRC Press
ISBN: 0429847041
Category : Business & Economics
Languages : en
Pages : 563

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Book Description
Exploratory Data Analysis Using R provides a classroom-tested introduction to exploratory data analysis (EDA) and introduces the range of "interesting" – good, bad, and ugly – features that can be found in data, and why it is important to find them. It also introduces the mechanics of using R to explore and explain data. The book begins with a detailed overview of data, exploratory analysis, and R, as well as graphics in R. It then explores working with external data, linear regression models, and crafting data stories. The second part of the book focuses on developing R programs, including good programming practices and examples, working with text data, and general predictive models. The book ends with a chapter on "keeping it all together" that includes managing the R installation, managing files, documenting, and an introduction to reproducible computing. The book is designed for both advanced undergraduate, entry-level graduate students, and working professionals with little to no prior exposure to data analysis, modeling, statistics, or programming. it keeps the treatment relatively non-mathematical, even though data analysis is an inherently mathematical subject. Exercises are included at the end of most chapters, and an instructor's solution manual is available. About the Author: Ronald K. Pearson holds the position of Senior Data Scientist with GeoVera, a property insurance company in Fairfield, California, and he has previously held similar positions in a variety of application areas, including software development, drug safety data analysis, and the analysis of industrial process data. He holds a PhD in Electrical Engineering and Computer Science from the Massachusetts Institute of Technology and has published conference and journal papers on topics ranging from nonlinear dynamic model structure selection to the problems of disguised missing data in predictive modeling. Dr. Pearson has authored or co-authored books including Exploring Data in Engineering, the Sciences, and Medicine (Oxford University Press, 2011) and Nonlinear Digital Filtering with Python. He is also the developer of the DataCamp course on base R graphics and is an author of the datarobot and GoodmanKruskal R packages available from CRAN (the Comprehensive R Archive Network).

Author: Ronald K. Pearson
Publisher: CRC Press
ISBN: 0429847033
Category : Business & Economics
Languages : en
Pages : 563

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Book Description
Exploratory Data Analysis Using R provides a classroom-tested introduction to exploratory data analysis (EDA) and introduces the range of "interesting" – good, bad, and ugly – features that can be found in data, and why it is important to find them. It also introduces the mechanics of using R to explore and explain data. The book begins with a detailed overview of data, exploratory analysis, and R, as well as graphics in R. It then explores working with external data, linear regression models, and crafting data stories. The second part of the book focuses on developing R programs, including good programming practices and examples, working with text data, and general predictive models. The book ends with a chapter on "keeping it all together" that includes managing the R installation, managing files, documenting, and an introduction to reproducible computing. The book is designed for both advanced undergraduate, entry-level graduate students, and working professionals with little to no prior exposure to data analysis, modeling, statistics, or programming. it keeps the treatment relatively non-mathematical, even though data analysis is an inherently mathematical subject. Exercises are included at the end of most chapters, and an instructor's solution manual is available. About the Author: Ronald K. Pearson holds the position of Senior Data Scientist with GeoVera, a property insurance company in Fairfield, California, and he has previously held similar positions in a variety of application areas, including software development, drug safety data analysis, and the analysis of industrial process data. He holds a PhD in Electrical Engineering and Computer Science from the Massachusetts Institute of Technology and has published conference and journal papers on topics ranging from nonlinear dynamic model structure selection to the problems of disguised missing data in predictive modeling. Dr. Pearson has authored or co-authored books including Exploring Data in Engineering, the Sciences, and Medicine (Oxford University Press, 2011) and Nonlinear Digital Filtering with Python. He is also the developer of the DataCamp course on base R graphics and is an author of the datarobot and GoodmanKruskal R packages available from CRAN (the Comprehensive R Archive Network).

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309268745
Category : Medical
Languages : en
Pages : 157

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Book Description
Pharmaceutical companies, academic researchers, and government agencies such as the Food and Drug Administration and the National Institutes of Health all possess large quantities of clinical research data. If these data were shared more widely within and across sectors, the resulting research advances derived from data pooling and analysis could improve public health, enhance patient safety, and spur drug development. Data sharing can also increase public trust in clinical trials and conclusions derived from them by lending transparency to the clinical research process. Much of this information, however, is never shared. Retention of clinical research data by investigators and within organizations may represent lost opportunities in biomedical research. Despite the potential benefits that could be accrued from pooling and analysis of shared data, barriers to data sharing faced by researchers in industry include concerns about data mining, erroneous secondary analyses of data, and unwarranted litigation, as well as a desire to protect confidential commercial information. Academic partners face significant cultural barriers to sharing data and participating in longer term collaborative efforts that stem from a desire to protect intellectual autonomy and a career advancement system built on priority of publication and citation requirements. Some barriers, like the need to protect patient privacy, pre- sent challenges for both sectors. Looking ahead, there are also a number of technical challenges to be faced in analyzing potentially large and heterogeneous datasets. This public workshop focused on strategies to facilitate sharing of clinical research data in order to advance scientific knowledge and public health. While the workshop focused on sharing of data from preplanned interventional studies of human subjects, models and projects involving sharing of other clinical data types were considered to the extent that they provided lessons learned and best practices. The workshop objectives were to examine the benefits of sharing of clinical research data from all sectors and among these sectors, including, for example: benefits to the research and development enterprise and benefits to the analysis of safety and efficacy. Sharing Clinical Research Data: Workshop Summary identifies barriers and challenges to sharing clinical research data, explores strategies to address these barriers and challenges, including identifying priority actions and "low-hanging fruit" opportunities, and discusses strategies for using these potentially large datasets to facilitate scientific and public health advances.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309486165
Category : Science
Languages : en
Pages : 257

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Book Description
One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.

Author: Charles R. Severance
Publisher:
ISBN: 9781530051120
Category :
Languages : en
Pages : 242

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Book Description
Python for Everybody is designed to introduce students to programming and software development through the lens of exploring data. You can think of the Python programming language as your tool to solve data problems that are beyond the capability of a spreadsheet.Python is an easy to use and easy to learn programming language that is freely available on Macintosh, Windows, or Linux computers. So once you learn Python you can use it for the rest of your career without needing to purchase any software.This book uses the Python 3 language. The earlier Python 2 version of this book is titled "Python for Informatics: Exploring Information".There are free downloadable electronic copies of this book in various formats and supporting materials for the book at www.pythonlearn.com. The course materials are available to you under a Creative Commons License so you can adapt them to teach your own Python course.

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309170311
Category : Science
Languages : en
Pages : 317

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Book Description
Safe Passage: Astronaut Care for Exploration Missions sets forth a vision for space medicine as it applies to deep space voyage. As space missions increase in duration from months to years and extend well beyond Earth's orbit, so will the attendant risks of working in these extreme and isolated environmental conditions. Hazards to astronaut health range from greater radiation exposure and loss of bone and muscle density to intensified psychological stress from living with others in a confined space. Going beyond the body of biomedical research, the report examines existing space medicine clinical and behavioral research and health care data and the policies attendant to them. It describes why not enough is known today about the dangers of prolonged travel to enable humans to venture into deep space in a safe and sane manner. The report makes a number of recommendations concerning NASA's structure for clinical and behavioral research, on the need for a comprehensive astronaut health care system and on an approach to communicating health and safety risks to astronauts, their families, and the public.

Author: MIT Critical Data
Publisher: Springer
ISBN: 3319437429
Category : Medical
Languages : en
Pages : 435

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Book Description
This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 030948247X
Category : Science
Languages : en
Pages : 103

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Book Description
In an increasingly interconnected world, perhaps it should come as no surprise that international collaboration in science and technology research is growing at a remarkable rate. As science and technology capabilities grow around the world, U.S.-based organizations are finding that international collaborations and partnerships provide unique opportunities to enhance research and training. International research agreements can serve many purposes, but data are always involved in these collaborations. The kinds of data in play within international research agreements varies widely and may range from financial and consumer data, to Earth and space data, to population behavior and health data, to specific project-generated dataâ€"this is just a narrow set of examples of research data but illustrates the breadth of possibilities. The uses of these data are various and require accounting for the effects of data access, use, and sharing on many different parties. Cultural, legal, policy, and technical concerns are also important determinants of what can be done in the realms of maintaining privacy, confidentiality, and security, and ethics is a lens through which the issues of data, data sharing, and research agreements can be viewed as well. A workshop held on March 14-16, 2018, in Washington, DC explored the changing opportunities and risks of data management and use across disciplinary domains. The third workshop in a series, participants gathered to examine advisory principles for consideration when developing international research agreements, in the pursuit of highlighting promising practices for sustaining and enabling international research collaborations at the highest ethical level possible. The intent of the workshop was to explore, through an ethical lens, the changing opportunities and risks associated with data management and use across disciplinary domainsâ€"all within the context of international research agreements. This publication summarizes the presentations and discussions from the workshop.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309449383
Category : Medical
Languages : en
Pages : 269

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Book Description
Evidence from the public health sector demonstrates that health care is only one of the determinants of health, which also include genes, behavior, social factors, and the built environment. These contextual elements are key to understanding why health care organizations are motivated to focus beyond their walls and to consider and respond in unprecedented ways to the social needs of patients, including transportation needs. In June 2016 the National Academies of Sciences, Engineering, and Medicine held a joint workshop to explore partnerships, data, and measurement at the intersection of the health care and transportation sectors. This publication summarizes the presentations and discussions from the workshop.