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Cochrane Handbook for Systematic Reviews of Interventions

Cochrane Handbook for Systematic Reviews of Interventions PDF Author: Julian P. T. Higgins
Publisher: Wiley
ISBN: 9780470699515
Category : Medical
Languages : en
Pages : 672

Book Description
Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

Cochrane Handbook for Systematic Reviews of Interventions

Cochrane Handbook for Systematic Reviews of Interventions PDF Author: Julian P. T. Higgins
Publisher: Wiley
ISBN: 9780470699515
Category : Medical
Languages : en
Pages : 672

Book Description
Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

Doing Meta-Analysis with R

Doing Meta-Analysis with R PDF Author: Mathias Harrer
Publisher: CRC Press
ISBN: 1000435636
Category : Mathematics
Languages : en
Pages : 500

Book Description
Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered, including calculation and pooling of outcome measures, forest plots, heterogeneity diagnostics, subgroup analyses, meta-regression, methods to control for publication bias, risk of bias assessments and plotting tools. Advanced but highly relevant topics such as network meta-analysis, multi-three-level meta-analyses, Bayesian meta-analysis approaches and SEM meta-analysis are also covered. A companion R package, dmetar, is introduced at the beginning of the guide. It contains data sets and several helper functions for the meta and metafor package used in the guide. The programming and statistical background covered in the book are kept at a non-expert level, making the book widely accessible. Features • Contains two introductory chapters on how to set up an R environment and do basic imports/manipulations of meta-analysis data, including exercises • Describes statistical concepts clearly and concisely before applying them in R • Includes step-by-step guidance through the coding required to perform meta-analyses, and a companion R package for the book

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide PDF Author: Agency for Health Care Research and Quality (U.S.)
Publisher: Government Printing Office
ISBN: 1587634236
Category : Medical
Languages : en
Pages : 236

Book Description
This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Reproducibility and Replicability in Science

Reproducibility and Replicability in Science PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309486165
Category : Science
Languages : en
Pages : 257

Book Description
One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.

Introduction to Meta-Analysis

Introduction to Meta-Analysis PDF Author: Michael Borenstein
Publisher: John Wiley & Sons
ISBN: 1119964377
Category : Medical
Languages : en
Pages : 350

Book Description
This book provides a clear and thorough introduction to meta-analysis, the process of synthesizing data from a series of separate studies. Meta-analysis has become a critically important tool in fields as diverse as medicine, pharmacology, epidemiology, education, psychology, business, and ecology. Introduction to Meta-Analysis: Outlines the role of meta-analysis in the research process Shows how to compute effects sizes and treatment effects Explains the fixed-effect and random-effects models for synthesizing data Demonstrates how to assess and interpret variation in effect size across studies Clarifies concepts using text and figures, followed by formulas and examples Explains how to avoid common mistakes in meta-analysis Discusses controversies in meta-analysis Features a web site with additional material and exercises A superb combination of lucid prose and informative graphics, written by four of the world’s leading experts on all aspects of meta-analysis. Borenstein, Hedges, Higgins, and Rothstein provide a refreshing departure from cookbook approaches with their clear explanations of the what and why of meta-analysis. The book is ideal as a course textbook or for self-study. My students, who used pre-publication versions of some of the chapters, raved about the clarity of the explanations and examples. David Rindskopf, Distinguished Professor of Educational Psychology, City University of New York, Graduate School and University Center, & Editor of the Journal of Educational and Behavioral Statistics. The approach taken by Introduction to Meta-analysis is intended to be primarily conceptual, and it is amazingly successful at achieving that goal. The reader can comfortably skip the formulas and still understand their application and underlying motivation. For the more statistically sophisticated reader, the relevant formulas and worked examples provide a superb practical guide to performing a meta-analysis. The book provides an eclectic mix of examples from education, social science, biomedical studies, and even ecology. For anyone considering leading a course in meta-analysis, or pursuing self-directed study, Introduction to Meta-analysis would be a clear first choice. Jesse A. Berlin, ScD Introduction to Meta-Analysis is an excellent resource for novices and experts alike. The book provides a clear and comprehensive presentation of all basic and most advanced approaches to meta-analysis. This book will be referenced for decades. Michael A. McDaniel, Professor of Human Resources and Organizational Behavior, Virginia Commonwealth University

Income Maintenance Experiments

Income Maintenance Experiments PDF Author: United States. General Accounting Office
Publisher:
ISBN:
Category : Evaluation research (Social action programs)
Languages : en
Pages : 96

Book Description


Experimentation and Uncertainty Analysis for Engineers

Experimentation and Uncertainty Analysis for Engineers PDF Author: Hugh W. Coleman
Publisher: John Wiley & Sons
ISBN: 9780471121466
Category : Psychology
Languages : en
Pages : 298

Book Description
Now, in the only manual available with direct applications to the design and analysis of engineering experiments, respected authors Hugh Coleman and Glenn Steele have thoroughly updated their bestselling title to include the new methodologies being used by the United States and International standards committee groups.

Laboratory Experiments in the Social Sciences

Laboratory Experiments in the Social Sciences PDF Author: Murray Webster
Publisher: Elsevier
ISBN: 0080546145
Category : Education
Languages : en
Pages : 574

Book Description
Laboratory Experiments in the Social Sciences is the only book providing core information for researchers about the ways and means to conduct experiments. Its comprehensive regard for laboratory experiments encompasses "how-to explanations, investigations of philosophies and ethics, explorations of experiments in specific social science disciplines, and summaries of both the history and future of social science laboratories. No other book offers such a direct avenue to enlarging our knowledge in the social sciences.This collection of original chapters combines instructions and advice about the design of laboratory experiments in the social sciences with the array of other issues. While there are books on experimental design and chapters in more general methods books on design, theory, and ethical issues, no other book attempts to discuss the fundamental ideas of the philosophy of science or lays out the methods comprehensively or in such detail. Experimentation has recently prospered because of increasing interest in cross-disciplinary syntheses, and this book of advice, guidelines, and observations underline its potential and increasing importance.· Provides a comprehensive summary of issues in social science experimentation, from ethics to design, management, and financing· Offers "how-to" explanations of the problems and challenges faced by everyone involved in social science experiments· Pays attention to both practical problems and to theoretical and philosophical arguments· Defines commonalities and distinctions within and among experimental situations across the social sciences

Results of Experiments

Results of Experiments PDF Author: Canada. Experimental Station, Kentville, Nova Scotia
Publisher:
ISBN:
Category :
Languages : en
Pages : 660

Book Description


Notes on Hydrologic Activities

Notes on Hydrologic Activities PDF Author: United States. Inter-agency Committee on Water Resources
Publisher:
ISBN:
Category : Hydrology
Languages : en
Pages : 428

Book Description