Author: W. De Jong
Publisher: Elsevier
ISBN: 1483162990
Category : Medical
Languages : en
Pages : 568
Book Description
Experimental and Genetic Models of Hypertension
Experimental and Genetic Models of Hypertension
Author: W. De Jong
Publisher: Elsevier
ISBN: 1483162990
Category : Medical
Languages : en
Pages : 568
Book Description
Experimental and Genetic Models of Hypertension
Publisher: Elsevier
ISBN: 1483162990
Category : Medical
Languages : en
Pages : 568
Book Description
Experimental and Genetic Models of Hypertension
Comprehensive Hypertension E-Book
Author: Gregory Y. H. Lip
Publisher: Elsevier Health Sciences
ISBN: 0323070671
Category : Medical
Languages : en
Pages : 1247
Book Description
Here is today's most in-depth reference for any cardiologist, internist, or nephrologist interested in hypertension. Drawing from international experience in cardiology, physiology, and nephrology, Drs. Lip and Hall have assembled a group of section editors and contributors second to none. You'll find the long-term effects of primary and secondary hypertension and a lengthy section on hypertensions for special populations featured prominently. Prevention and treatment of hypertension are covered in detail, from lifestyle and diet issues to drug choice and delivery, and the section on comparison of guidelines is unique to this book. Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume. See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations. Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis. Get specific insight into prevention and treatment of hypertension in special populations. Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.
Publisher: Elsevier Health Sciences
ISBN: 0323070671
Category : Medical
Languages : en
Pages : 1247
Book Description
Here is today's most in-depth reference for any cardiologist, internist, or nephrologist interested in hypertension. Drawing from international experience in cardiology, physiology, and nephrology, Drs. Lip and Hall have assembled a group of section editors and contributors second to none. You'll find the long-term effects of primary and secondary hypertension and a lengthy section on hypertensions for special populations featured prominently. Prevention and treatment of hypertension are covered in detail, from lifestyle and diet issues to drug choice and delivery, and the section on comparison of guidelines is unique to this book. Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume. See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations. Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis. Get specific insight into prevention and treatment of hypertension in special populations. Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.
Genetics of Hypertension
Author: Xi Cheng
Publisher: Biota Publishing
ISBN: 161504695X
Category : Medical
Languages : en
Pages : 67
Book Description
Hypertension, or elevated blood pressure, is a major risk factor for various cardiovascular, renal diseases, and stroke. The form of hypertension with no identifiable cause is referred to as Essential Hypertension. Familial studies indicate that Essential Hypertension is heritable and, thereby, classical genetic approaches have been applied on both human and other mammalian models of hypertension to map the locations of the allelic variants within quantitative trait loci for blood pressure. The post genome era has further elevated this area of research into large-scale genome-wide association studies of hypertension in humans. Collectively, these studies have resulted in the prioritization and cataloging of several genomic regions containing allelic variants as candidates linked or associated with essential hypertension. Further, they are providing evidence to suggest that the inheritance of hypertension is rather complex, encompassing multiple variants both within protein-coding and non-coding annotations, each of which may act independently or interactively with other genes and/or environmental factors to differentially regulate blood pressure. This book provides an overview of the various methods employed to study the genetics of hypertension and discuss the progress and prospects of this area of research that may contribute towards individualized clinical management of hypertension in the future.
Publisher: Biota Publishing
ISBN: 161504695X
Category : Medical
Languages : en
Pages : 67
Book Description
Hypertension, or elevated blood pressure, is a major risk factor for various cardiovascular, renal diseases, and stroke. The form of hypertension with no identifiable cause is referred to as Essential Hypertension. Familial studies indicate that Essential Hypertension is heritable and, thereby, classical genetic approaches have been applied on both human and other mammalian models of hypertension to map the locations of the allelic variants within quantitative trait loci for blood pressure. The post genome era has further elevated this area of research into large-scale genome-wide association studies of hypertension in humans. Collectively, these studies have resulted in the prioritization and cataloging of several genomic regions containing allelic variants as candidates linked or associated with essential hypertension. Further, they are providing evidence to suggest that the inheritance of hypertension is rather complex, encompassing multiple variants both within protein-coding and non-coding annotations, each of which may act independently or interactively with other genes and/or environmental factors to differentially regulate blood pressure. This book provides an overview of the various methods employed to study the genetics of hypertension and discuss the progress and prospects of this area of research that may contribute towards individualized clinical management of hypertension in the future.
Experimental and Genetic Models of Hypertension
Author: Wybren de Jong
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 664
Book Description
Hardbound. This volume is a worthy successor to volume 4 by virtue of its focus on the recent conceptual revolution in fundamental hypertension research. Without neglecting the heritage of earlier achievements, it highlights such brilliant breakthroughs in molecular genetics as the creation of transgenic animals as a source of a new pathogenesis of hypertension.A core of (patho)physiological mechanisms operative in experimental hypertension is provided, including several which act to maintain a normotensive state. The volume provides background and technical information on the use of different models of hypertension in a variety of animal species. A wealth of new information regarding the several different complications observed in genetic and other models of hypertension, as well as new animal models dedicated to these aspects, are also presented. Furthermore, new chapters addressing genotyping and the use of transgenics in hypertension are included.
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 664
Book Description
Hardbound. This volume is a worthy successor to volume 4 by virtue of its focus on the recent conceptual revolution in fundamental hypertension research. Without neglecting the heritage of earlier achievements, it highlights such brilliant breakthroughs in molecular genetics as the creation of transgenic animals as a source of a new pathogenesis of hypertension.A core of (patho)physiological mechanisms operative in experimental hypertension is provided, including several which act to maintain a normotensive state. The volume provides background and technical information on the use of different models of hypertension in a variety of animal species. A wealth of new information regarding the several different complications observed in genetic and other models of hypertension, as well as new animal models dedicated to these aspects, are also presented. Furthermore, new chapters addressing genotyping and the use of transgenics in hypertension are included.
Hypertension, Physiopathology and Treatment
Author: Jacques Genest
Publisher: McGraw-Hill Companies
ISBN:
Category : Medical
Languages : en
Pages : 1386
Book Description
Publisher: McGraw-Hill Companies
ISBN:
Category : Medical
Languages : en
Pages : 1386
Book Description
Genetics of Hypertension
Author: Anna F. Dominiczak
Publisher: Elsevier Health Sciences
ISBN: 0444514562
Category : Medical
Languages : en
Pages : 284
Book Description
Classic and modern tools of genetics have been applied to hypertension research for some 20 years. This volume in the Handbook of Hypertension series aims to go beyond a simple summary of discoveries and provides a critical commentary on many controversial issues. It will be particularly useful for clinician scientists at all stages of their careers, graduate students and post-doctoral scientists as well as all those interested in cardiovascular medicine and research throughout the entire spectrum from bench to bedside. As in every relatively young area of research, the initial excitement over the early positive observations has not always been confirmed by subsequent larger studies with greater statistical power. Issues related to current recommendations on design of studies and their analysis are therefore included. Pharmacogenetics and pharmacogenomics have been the subjects of many debates in recent years and are of particular importance in hypertension as life-long treatments, frequently with multiple drugs are given to millions of people world-wide. A critical appraisal of this controversial topic is provided. Several chapters on experimental genetics of hypertension with a special focus on physiological genomics are also included.
Publisher: Elsevier Health Sciences
ISBN: 0444514562
Category : Medical
Languages : en
Pages : 284
Book Description
Classic and modern tools of genetics have been applied to hypertension research for some 20 years. This volume in the Handbook of Hypertension series aims to go beyond a simple summary of discoveries and provides a critical commentary on many controversial issues. It will be particularly useful for clinician scientists at all stages of their careers, graduate students and post-doctoral scientists as well as all those interested in cardiovascular medicine and research throughout the entire spectrum from bench to bedside. As in every relatively young area of research, the initial excitement over the early positive observations has not always been confirmed by subsequent larger studies with greater statistical power. Issues related to current recommendations on design of studies and their analysis are therefore included. Pharmacogenetics and pharmacogenomics have been the subjects of many debates in recent years and are of particular importance in hypertension as life-long treatments, frequently with multiple drugs are given to millions of people world-wide. A critical appraisal of this controversial topic is provided. Several chapters on experimental genetics of hypertension with a special focus on physiological genomics are also included.
Use of Laboratory Animals in Biomedical and Behavioral Research
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309038391
Category : Science
Languages : en
Pages : 113
Book Description
Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Publisher: National Academies Press
ISBN: 0309038391
Category : Science
Languages : en
Pages : 113
Book Description
Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Endocrine Hypertension
Author: Karel Pacak
Publisher:
ISBN: 9781573314183
Category : Adrenal Gland Neoplasms
Languages : en
Pages : 0
Book Description
Several genetic, biochemical and radiologic discoveries have impacted the management of endocrine hypertension, while surgical procedures have revolutionized treatment of patients with endocrine hypertension. This text contains the proceedings of a 2001 workshop on the topic.
Publisher:
ISBN: 9781573314183
Category : Adrenal Gland Neoplasms
Languages : en
Pages : 0
Book Description
Several genetic, biochemical and radiologic discoveries have impacted the management of endocrine hypertension, while surgical procedures have revolutionized treatment of patients with endocrine hypertension. This text contains the proceedings of a 2001 workshop on the topic.
Methods of Behavior Analysis in Neuroscience
Author: Jerry J. Buccafusco
Publisher: CRC Press
ISBN: 1420041819
Category : Medical
Languages : en
Pages : 341
Book Description
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Publisher: CRC Press
ISBN: 1420041819
Category : Medical
Languages : en
Pages : 341
Book Description
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Good Research Practice in Non-Clinical Pharmacology and Biomedicine
Author: Anton Bespalov
Publisher: Springer Nature
ISBN: 3030336565
Category : Cardiology
Languages : en
Pages : 424
Book Description
This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
Publisher: Springer Nature
ISBN: 3030336565
Category : Cardiology
Languages : en
Pages : 424
Book Description
This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.