Author: Mark Alexander EngelhardtPublisher:
ISBN:
Category :
Languages : en
Pages : 626
Book Description
Experimental and Computational Investigations of Nucleic Acid Structure
Author: Mark Alexander EngelhardtPublisher:
ISBN:
Category :
Languages : en
Pages : 626
Book Description
Computational studies of RNA and DNA
Author: Jirí ŠponerPublisher: Springer Science & Business Media
ISBN: 1402048513
Category : Science
Languages : en
Pages : 638
Book Description
This book integrates modern computational studies of nucleic acids, ranging from advanced electronic structure quantum chemical calculations through explicit solvent molecular dynamics (MD) simulations up to mesoscopic modelling, with the main focus given to the MD field. It gives an equal emphasis to the leading methods and applications while successes as well as pitfalls of the computational techniques are discussed.
RNA Structure and Dynamics
Author: Jienyu DingPublisher: Springer Nature
ISBN: 1071626876
Category : Science
Languages : en
Pages : 256
Book Description
This volume provides a wide spectrum of multidisciplinary approaches for studying RNA structure and dynamics, including detailed accounts of experimental and computational procedures. Chapters guide readers through cryo-electron microscopy, crystallography, isothermal titration calorimetry, small angle X-ray scattering, single-molecule Förster Energy transfer, X-ray free electron laser, atomic force microscopy, computational simulation, and prediction. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, RNA Structure and Dynamics aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.
Experimental and Computational Studies of DNA Structure Using the Hydroxyl Radical as a Chemical Probe
Author: Jason Adam GreenbaumPublisher:
ISBN:
Category : DNA damage
Languages : en
Pages : 388
Book Description
Computational Investigations Into Nucleic Acid-related Chemistry
Author: Haining LiuRadiation Induced Molecular Phenomena in Nucleic Acids
Author: Manoj ShuklaPublisher: Springer Science & Business Media
ISBN: 1402081847
Category : Science
Languages : en
Pages : 677
Book Description
Comprehensive theoretical and experimental analysis of UV-radiation and low energy electron induced phenomena in nucleic acid bases (NABs) and base assemblies are presented in this book. NABs are highly photostable; the absorbed energy is dissipated in the form of ultrafast nonradiative decay. This book highlights the possible mechanisms of these phenomena which is important for all living species and discusses technical challenges in exploration of these processes.
Computational Molecular Biology
Author: Jerzy LeszczynskiPublisher: Elsevier Science Limited
ISBN: 0444500308
Category : Science
Languages : en
Pages : 645
Book Description
This book covers applications of computational techniques to biological problems. These techniques are based by an ever-growing number of researchers with different scientific backgrounds - biologists, chemists, and physicists. The rapid development of molecular biology in recent years has been mirrored by the rapid development of computer hardware and software. This has resulted in the development of sophisticated computational techniques and a wide range of computer simulations involving such methods. Among the areas where progress has been profound is in the modeling of DNA structure and function, the understanding at a molecular level of the role of solvents in biological phenomena, the calculation of the properties of molecular associations in aqueous solutions, computationally assisted drug design, the prediction of protein structure, and protein - DNA recognition, to mention just a few examples. This volume comprises a balanced blend of contributions covering such topics. They reveal the details of computational approaches designed for biomoleucles and provide extensive illustrations of current applications of modern techniques. A broad group of readers ranging from beginning graduate students to molecular biology professions should be able to find useful contributions in this selection of reviews.
Chemical Synthetic Biology
Author: Pier Luigi LuisiPublisher: John Wiley & Sons
ISBN: 1119990300
Category : Science
Languages : en
Pages : 269
Book Description
Chemistry plays a very important role in the emerging field of synthetic biology. In particular, chemical synthetic biology is concerned with the synthesis of chemical structures, such as proteins, that do not exist in nature. With contributions from leading international experts, Chemical Synthetic Biology shows how chemistry underpins synthetic biology. The book is an essential guide to this fascinating new field, and will find a place on the bookshelves of researchers and students working in synthetic chemistry, synthetic and molecular biology, bioengineering, systems biology, computational genomics, and bioinformatics.
Molecular Biology of the Cell
Author: Molecular Modeling of Proteins
Author: Andreas KukolPublisher: Humana Press
ISBN: 9781493954919
Category : Science
Languages : en
Pages : 474
Book Description
Molecular Modeling of Proteins, Second Edition provides a theoretical background of various methods available and enables non-specialists to apply methods to their problems by including updated chapters and new material not covered in the first edition. This detailed volume opens by featuring classical and advanced simulation methods as well as methods to set-up complex systems such as lipid membranes and membrane proteins and continues with chapters devoted to the simulation and analysis of conformational changes of proteins, computational methods for protein structure prediction, usage of experimental data in combination with computational techniques, as well as protein-ligand interactions, which are relevant in the drug design process. Written for the highly successful Methods in Molecular Biology series, chapters include thorough introductions, step-by-step instructions and notes on troubleshooting and avoiding common pitfalls. Update-to-date and authoritative, Molecular Modeling of Proteins, Second Edition aims to aid researchers in the physical, chemical and biosciences interested in utilizing this powerful technology.