Evolutionary Systems Biology of Virus-host Interactions PDF Download

Author: Anderson Fernandes de Brito
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Author: Pierre Pontarotti
Publisher: Springer
ISBN: 3319615696
Category : Science
Languages : en
Pages : 396

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Book Description
This book presents 19 selected contributions to the 20th Evolutionary Biology Meeting in Marseille, which took place in September 2016. They are grouped under the following major themes: · Self/Nonself Evolution · Species Evolution and Evolution of Complex Traits · Methods and Concepts The aims of the annual meetings in Marseille – which bring together leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research – are to promote the exchange of ideas and to encourage interdisciplinary collaborations. Offering a revealing overview of the latest findings in the field of evolutionary biology, this book represents an invaluable source of information for scientists, teachers and advanced students alike.

Author: Luis P. Villarreal
Publisher: Amer Society for Microbiology
ISBN: 9781555813093
Category : Science
Languages : en
Pages : 395

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Viruses and the Evolution of Life is an intriguing presentation of the virus–host relationship, as revealed through an examination of host evolution. This new volume avails the informed reader of a new perspective on the evolution of life while targeting the expert reader with discussions of specific scientific literature. Addresses the adaptation and evolution of viruses and, more importantly, the role of viruses in evolutionary biology Develops integrated themes for study of virology Contributes valuable information to the understanding of the virus–host relationship Integrates the relationship between genetic parasites found in host genomes with the virology of the host Communicates basic principles to the informed reader while presenting a scholarly evaluation of literature to challenge the specialist Written by one of the foremost experts in the field

Author: Marilena Aquino de Muro
Publisher: Springer Nature
ISBN: 107162895X
Category : Medical
Languages : en
Pages : 204

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This detailed volume spotlights methods to investigate a variety of virus-host interactions in humans, other mammals, fish, or insects. It explores viruses such as white spot syndrome virus (WSSV), honeybee viruses, Nipah virus, EBV, SVCV, HSV-1, HIV-1, A H1N1, and SARS-CoV-2, as well as applications of techniques such as qPCR, serum antibody responses, 4C analysis, cell membrane fusion, biosensors, computational modelling, quantitative proteomics, and other genetic tools to decipher those viral infections and interactions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Virus-Host Interactions: Methods and Protocols serves as a valuable resource for researchers both in academia and in the biosciences industry who are engaged in the search for a better understanding of threatening virus-hosts interactions, virus detection, their characterization, and ultimately their taming and control.

Author: Ricard Solé
Publisher: Princeton University Press
ISBN: 0691185115
Category : Science
Languages : en
Pages : 239

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How complex systems theory sheds new light on the adaptive dynamics of viral populations Viruses are everywhere, infecting all sorts of living organisms, from the tiniest bacteria to the largest mammals. Many are harmful parasites, but viruses also play a major role as drivers of our evolution as a species and are essential regulators of the composition and complexity of ecosystems on a global scale. This concise book draws on complex systems theory to provide a fresh look at viral origins, populations, and evolution, and the coevolutionary dynamics of viruses and their hosts. New viruses continue to emerge that threaten people, crops, and farm animals. Viruses constantly evade our immune systems, and antiviral therapies and vaccination campaigns can be powerless against them. These unique characteristics of virus biology are a consequence of their tremendous evolutionary potential, which enables viruses to quickly adapt to any environmental challenge. Ricard Solé and Santiago Elena present a unified framework for understanding viruses as complex adaptive systems. They show how the application of complex systems theory to viral dynamics has provided new insights into the development of AIDS in patients infected with HIV-1, the emergence of new antigenic variants of the influenza A virus, and other cutting-edge advances. Essential reading for biologists, physicists, and mathematicians interested in complexity, Viruses as Complex Adaptive Systems also extends the analogy of viruses to the evolution of other replicators such as computer viruses, cancer, and languages.

Author: Joshua Weitz
Publisher: Princeton University Press
ISBN: 0691161542
Category : Science
Languages : en
Pages : 354

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When we think about viruses we tend to consider ones that afflict humans—such as those that cause influenza, HIV, and Ebola. Yet, vastly more viruses infect single-celled microbes. Diverse and abundant, microbes and the viruses that infect them are found in oceans, lakes, plants, soil, and animal-associated microbiomes. Taking a vital look at the "microscopic" mode of disease dynamics, Quantitative Viral Ecology establishes a theoretical foundation from which to model and predict the ecological and evolutionary dynamics that result from the interaction between viruses and their microbial hosts. Joshua Weitz addresses three major questions: What are viruses of microbes and what do they do to their hosts? How do interactions of a single virus-host pair affect the number and traits of hosts and virus populations? How do virus-host dynamics emerge in natural environments when interactions take place between many viruses and many hosts? Emphasizing how theory and models can provide answers, Weitz offers a cohesive framework for tackling new challenges in the study of viruses and microbes and how they are connected to ecological processes—from the laboratory to the Earth system. Quantitative Viral Ecology is an innovative exploration of the influence of viruses in our complex natural world.

Author: Paula Tennant
Publisher: Academic Press
ISBN: 0128111941
Category : Science
Languages : en
Pages : 393

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Book Description
Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology provides an up-to-date introduction to human, animal and plant viruses within the context of recent advances in high-throughput sequencing that have demonstrated that viruses are vastly greater and more diverse than previously recognized. It covers discoveries such as the Mimivirus and its virophage which have stimulated new discussions on the definition of viruses, their place in the current view, and their inherent and derived ‘interactomics’ as defined by the molecules and the processes by which virus gene products interact with themselves and their host’s cellular gene products. Further, the book includes perspectives on basic aspects of virology, including the structure of viruses, the organization of their genomes, and basic strategies in replication and expression, emphasizing the diversity and versatility of viruses, how they cause disease and how their hosts react to such disease, and exploring developments in the field of host-microbe interactions in recent years. The book is likely to appeal, and be useful, to a wide audience that includes students, academics and researchers studying the molecular biology and applications of viruses Provides key insights into recent technological advances, including high-throughput sequencing Presents viruses not only as formidable foes, but also as entities that can be beneficial to their hosts and humankind that are helping to shape the tree of life Features exposition on the diversity and versatility of viruses, how they cause disease, and an exploration of virus-host interactions

Author: Nikos Vasilakis
Publisher: Caister Academic Press Limited
ISBN: 9781910190210
Category : Medical
Languages : en
Pages : 0

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Arthropod-borne viruses (arboviruses) are the causative agents of significant morbidity and mortality among humans and domestic animals globally. They are maintained in complex biological life cycles, involving a primary vertebrate host and a primary arthropod vector. While all known arboviruses are zoonotic pathogens, their emergence as human pathogens is associated with dramatic increases of human population growth leading to uncontrolled urbanization, changes in land and water use, changes in agricultural practices, new irrigation systems and deforestation. This book brings together a panel of expert arbovirologists to produce a timely review of the rapidly expanding arbovirus research literature. In addition authors identify the most pressing questions that remain to be answered, thus providing a stimulus for future research. Topics include: taxonomy, genome organization, virus-host and virus-vector interactions, evolutionary history, role of vertical transmission in arbovirus maintenance and evolution, epidemiology, arbovirus replication, pathogenesis, arbovirus diagnostics and control, including vaccines, novel anti-viral drugs, RNA interference and genetically modified vectors. Essential reading for every arbovirologist and highly recommended for all virologists and public health officials. [Subject: Microbiology, Life Science, Arbovirology, Virology, Taxonomy, Epidemiology]

Author: Esteban Domingo
Publisher: Elsevier
ISBN: 0080564968
Category : Science
Languages : en
Pages : 573

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New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts

Author: Günther Witzany
Publisher: Springer Science & Business Media
ISBN: 940074899X
Category : Science
Languages : en
Pages : 432

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Book Description
A renaissance of virus research is taking centre stage in biology. Empirical data from the last decade indicate the important roles of viruses, both in the evolution of all life and as symbionts of host organisms. There is increasing evidence that all cellular life is colonized by exogenous and/or endogenous viruses in a non-lytic but persistent lifestyle. Viruses and viral parts form the most numerous genetic matter on this planet.