Author: Edwin Benjamin Rajo GomezPublisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Evaluation of the Effects of Endophyte-Infected Tall Fescue Consumption on the Pulmonary Arterial Pressure of Beef Cattle
Author: Edwin Benjamin Rajo GomezPublisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Effect of Endophyte-infected Tall Fescue on Hepatic Gene Expression in Cattle
Author: Jenny Katherine BryantPublisher:
ISBN:
Category : Electronic dissertations
Languages : en
Pages : 181
Book Description
Fescue toxicosis may result from the intake of ergot alkaloids found in endophyteinfected (E+) tall fescue. The liver if the major organ involved in the pathology of fescue toxicosis, as it is the site where the toxic ergot alkaloids are metabolized. A study performed with rats consuming and E+ diet reported increased expression of Phase I detoxification enzymes and a decreased expression of antioxidants, to suggest an increase of cellular oxidative stress. This study was performed to determine if intake of E+ fescue had the same effect on the expression of detoxification enzymes and antioxidants in cattle. A second objective of this study was to examine changes in the hepatic transcriptome that occur when cattle consume E+ fescue. Missouri- (MO; n=10; 513.6±1.3 Kg BW) and Oklahoma- (OK; n=10; 552.8±12.0 Kg BW) derived Angus steers, maintained at 19-22°C (TN) air temperature for 8 days and then maintained at cycling heat stress for an additional 10 days (26°C night Ta; 36°C day Ta:HS). Cattle were fed diets containing either endophyte-free (E-) or E+ seed (30 [microgram] ergovaline/Kg BW/day) and feed intake (FI) was recorded daily. Blood and liver tissue samples were collected during pretreatment followed by blood samples at Day 4, 11, and 17 and liver tissue samples were collected again on Day 7 and 18. Consumption of E+ fescue resulted in significantly reduced (p!0.05) feed intake in both the TN and HS periods when compared to the E- group. There was also a significantly (p!0.05) lower serum prolactin concentration of E+ steers when compared to E- steers in both the TN and HS periods. These results confirm that E+ steers were experiencing the physiological conditions associated with fescue toxicosis. Real-time PCR was performed to determine expression of selected hepatic Phase I detoxification enzymes and specific antioxidant proteins. Illumina deep sequencing was performed on TN samples from selected fescue-naïve OK steers. Tiling of the sequences to a ~23,500 member reference allowed for the quantification of mRNA transcript abundance in each sample. Real-time PCR demonstrated that cattle consuming E+ fescue did not a significant change in the expression of Phase I detoxification enzymes or antioxidants. Illumina transcriptome analysis confirmed that E+ fescue did not have any significant effect on the expression of selected Phase I genes; however, there were 76 genes whose expression was significantly affected by E+ fescue, including a number of genes involved in !-oxidation of fatty acids, oxidative phosphorylation, Phase II detoxification, antioxidant activity and the stress response. Illumina deep sequencing aided in compiling a list of genes, which should undergo further study to identify the nature of their connection to the clinical signs of fescue toxicosis.
A Comparison of the Management Strategies Used to Mitigate Or Alleviate the Effects of Endophyte-infected Tall Fescue on Beef Cattle Performance
Author: Jamie HawleyPublisher:
ISBN:
Category : Beef cattle
Languages : en
Pages : 206
Book Description
Effect of Consumption of Endophyte-infected Tall Fescue on Embryo Survival in Beef Heifers
Author: Carla Ann ManessPublisher:
ISBN:
Category : Cattle
Languages : en
Pages : 168
Book Description
Fescue Toxicosis and Management
Author: Craig A. RobertsPublisher: John Wiley & Sons
ISBN: 0891186301
Category : Technology & Engineering
Languages : en
Pages : 32
Book Description
Fescue toxicosis continues to be one of the most devastating problems in forage–livestock agriculture. Because there is presently no cure, using the most up-to-date management and prevention approaches are crucial. The 2nd edition of this important guide presents an easy-to-understand description of this complex problem, along with recommendations that are practical for real farm use.
Effects of Feeding Endophyte-infected Tall Fescue Seed on Beef Cattle Performance, Hepatic Enzyme Activity, Lipid Oxidation, Metmyoglobin Reductase Activity, and Mitochondrial Lipid Composition
Author: Brandon Jermaine McClentonPublisher:
ISBN:
Category :
Languages : en
Pages : 98
Book Description
The objective of this study was to determine the effects of feeding endophyte-infected tall fescue seed to Angus steers on average daily gain, carcass characteristics, ergovaline concentration, lipid oxidation, hepatic enzyme activity, metmyoglobin reductase activity, and mitochondrial lipid composition. Animals were blocked into light, medium, and heavy body weight groups and were randomly assigned to either a KY31 seed treatment (6796 ppb ergovaline; 20 μg/kg BW; E+; n = 6) or a KY32 control ( 100 ppb; E-; n = 6). There was a 2- way treatment × time interaction effect on ADG (P
Impacts of Endophyte Infected Fescue on Cow Calf Production and Evaluation of Grazing Pressures on Endophyte Free Fescue Pastures
Author: Bolaji AremuPublisher:
ISBN:
Category : Beef cattle
Languages : en
Pages : 442
Book Description
Fescue Toxicosis and Management
Author: Craig Arthur RobertsPublisher: ASA-CSSA-SSSA
ISBN: 9780891181774
Category : Electronic books
Languages : en
Pages : 20
Book Description
Author: Jessica Renee Bussard
Author: Alese Grey Parks