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Author: National Research Council Publisher: National Academies Press ISBN: 0309175771 Category : Medical Languages : en Pages : 276
Book Description
The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.
Author: National Research Council Publisher: National Academies Press ISBN: 0309175771 Category : Medical Languages : en Pages : 276
Book Description
The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.
Author: R. J. Heitzman Publisher: Wiley-Blackwell ISBN: 9780632037865 Category : Medical Languages : en Pages : 512
Book Description
The purpose of this second edition is to bring together the current rapid developments and activities in residues of veterinary drugs within the European Community. The EEC legislation is summarised. There is information on the Reference Laboratories, the Maximum Residues Limits (MRL) and the criteria for the methods to be used for routine analysis of residues by Member States and third countries wishing to export meat to the EC. The current state of examination of residues practised and the analytical methods used in Member States is described in detail. There is a section on quality assurance in the laboratory and also supporting information on residues and chemical/physical data of the most important veterinary drugs
Author: Joint FAO/WHO Expert Committee on Food Additives. Meeting Publisher: World Health Organization ISBN: 9241209542 Category : Business & Economics Languages : en Pages : 144
Book Description
This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), including a hypothesis-driven decision tree approach for the safety evaluation of residues of veterinary drugs; comments on the Committee for Veterinary Products for Medicinal Use reflection paper on the new approach developed by JECFA for exposure and maximum residue limit (MRL) assessment of residues; residues of veterinary drugs in honey and possible approaches to derive MRLs for this commodity; comments on a paper entitled "Risk-assessment policies: Differences among jurisdictions"; and the use of no-observed-effect level (NOEL) and no-observed-adverse-effect level (NOAEL) in JECFA assessments. Summaries follow of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: three antimicrobial agents (avilamycin, tilmicosin, tylosin), one authentic (triclabendazole), one production aid (melengestrol acetate), two antimicrobial agents and production aids (monesin and narasin), a glucocorticosteroid (dexamethasone) and an antimicrobial agent ands contaminant (malachite green). Annexed to the report is a summary of the Committee's recommendations on these drugs, including acceptable daily intakes (ADI's) and proposed MRL's.
Author: V.K. Agarwal Publisher: Springer Science & Business Media ISBN: 1461533562 Category : Medical Languages : en Pages : 260
Book Description
In the last three decades. use of antibiotics/drugs in animal husbandry programs has grown tremendously. Antibiotics/drugs are used therapeutically to cure diseases. and subtherapeutically to control the outbreak of diseases, improve feed efficiency and promote growth. The presence of antibiotic/drug residues in food products of animal origin. i.e •• meat, poultry and milk, can be a potential health hazard to consumers. Significant research is being done to develop new methods or to improve on existing methods to confirm and quantitatively determine the antibiotic/drug residues in meat, poultry and milk. This book covers recent development and application of various analytical techniques for the determination of antibiotic/drug residues in food products of animal origin. I thank the authors for their time and efforts in preparing the manuscripts and "all the reviewers for reviewing the manuscripts. I also thank to the Division of Agricultural and Food Chemistry of the American Chemical Society for sponsoring the symposium and Hewlett Packard, Palo Alto, CA, Perkin Elmer Corp., Norwalk, CT, Millipore Corporation, Milford, MA, and Kraft General Foods, Glenview, IL, for their generous financial support for the symposium. Vipin K. Agarwal New Haven, CT v CONTENTS Importance of Laboratory Validations and Accurate Descriptions of Analytical Procedures for Drug Residues in Foods ................. .
Author: Joint FAO/WHO Expert Committee on Food Additives Publisher: World Health Organization ISBN: 9241209003 Category : Business & Economics Languages : en Pages : 104
Book Description
This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of veterinary drugs within the terms of reference of JECFA, including compounds without an ADI or MRL; recommendations on principles and methods in derivation of MRLs, including a new procedure for estimating chronic dietary intakes; the use of a spreadsheet-based procedure for the statistical evaluati.
Author: Joint FAO/WHO Expert Committee on Food Additives. Meeting Publisher: World Health Organization ISBN: 9241209399 Category : Business & Economics Languages : en Pages : 89
Book Description
This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of veterinary drugs within the terms of reference of JECFA, including compounds without an ADI or MRL; recommendations on principles and methods in derivation of MRLs, including a new procedure for estimating chronic dietary intakes; the use of a spreadsheet-based procedure for the statistical evaluation of residue depletion data; a revised approach for the derivation of microbiological ADIs; and the Committee's review of and comments on documents provided by the Codex Committee on Residues of Veterinary Drugs. Summaries follow of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: three antimicrobial agents (colistin, erythromycin, flumequine), two production aids (melengestrol acetate, ractopamine hydrochloride, an insecticide (trichlorfon (metrifonate)), and an anthelminthic (triclabendazole). In addition, the attempt by the Committee to use tylosin as an example to investigate if evaluations are possible based on published data in the absence of data submissions from sponsors is described. Annexed to the report is a summary of the Committee's recommendations on these drugs, including acceptable daily intakes and proposed maximum residue limits.
Author: World Health Organization Publisher: World Health Organization ISBN: 9241660570 Category : Business & Economics Languages : en Pages : 96
Book Description
This volume contain toxicological monographs prepared at the 66th meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) which met in Rome, Italy in February 2006. These summarise data on two veterinary drug residues evaluated by the Committee, the antimicrobial agents colistin and erythromycin. For the third antimicrobial agent, tylosin, a toxicological monograph has not been prepared, as no data were submitted, and a brief review of the tocicological information available in the scientific peer-reviewed literature did not allow an evaluation of the compound.
Author: World Health Organization Publisher: World Health Organization ISBN: 9241209976 Category : Business & Economics Languages : en Pages : 128
Book Description
This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of residues of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) including MRLs for generic fish species acute reference doses (ARfDs) for veterinary drugs an approach for dietary exposure assessment of compounds used for multiple purposes (i.e. veterinary drugs and pesticides) dietary exposure assessment for less-than-lifetime exposure and the assessment of short-term (90-day and 12-month) studies in dogs. Summaries follow of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: two insecticides (diflubenzuron and teflubenzuron) an antiparasitic agent (ivermectin) an ectoparasiticide (sisapronil) and a B2-adrenoceptor agonist (zilpaterol hydrochloride). In addition the Committee considered issues raised in concern forms from the Codex Committee on Residues of Veterinary Drugs in Foods on lasalocid sodium an antiparasitic agent. Annexed to the report is a summary of the Committee's recommendations on these drugs including acceptable daily intakes (ADIs) ARfDs and proposed MRLs.
Author: Publisher: World Health Organization ISBN: 9240016252 Category : Medical Languages : en Pages : 174
Book Description
The monographs contained in this volume were prepared at the eighty-eighth meeting of the Joint Food and Agriculture Organization of the United Nations (FAO)/World Health Organization (WHO) Expert Committee on Veterinary drugs (JECFA), which met at WHO headquarters in Rome, Italy, 22–31 October 2019. These monographs summarize the data on selected veterinary drugs reviewed by the Committee.
Author: National Research Council
Author: National Research Council
Author: R. J. Heitzman
Author: Joint FAO/WHO Expert Committee on Food Additives. Meeting
Author: V.K. Agarwal
Author: Joint FAO/WHO Expert Committee on Food Additives
Author: Joint FAO/WHO Expert Committee on Food Additives. Meeting
Author: World Health Organization
Author: World Health Organization
Author: 
Author: World Health Organization