Author: H. Fröhlich
Publisher: Springer Science & Business Media
ISBN: 3642691862
Category : Medical
Languages : en
Pages : 234
Book Description
The articles in this volume are based on papers presented at the International Symposium in Bad Neuenahr November 29 - December 1, 1982. The meeting was directed by H. Frohlich and was sponsored by IBM Deutschland through its Science and Education Programs Department. Contents Coherence in Biology H. Frohlich . Coherent Excitations and Raman Effect F. Drissler and L. Santo (With 4 Figures) 6 The Non-thermal Effect of Millimeter Wave Radiation on the Puffing of Giant Chromosomes F. Kremer, C. Koschnitzke, L. Santo, P. Quick, and A. Poglitsch (With 4 Figures) 10 Nonthermal Resonant Effects of 42 GHz Microwaves on the Growth of Yeast Cultures W. Grundler, F. Keilmann, V. Putterlik, L. Santo, D. Strube, and I. Zimmermann (With 15 Figures) 21 On the Microwave Response of the Drosophila Melanogaster G. Nimtz (With 5 Figures) 38 Effects of Low-level Millimeter Waves on Cellular and Subcellular Systems S. M. Motzkin, L. Benes, N. Block, B. Israel, N. May, J. Kuriyel, L. Birenbaum, S. Rosenthal, and Q. Han (With 12 Figures). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 Millimeter-wave and Far-infrared Spec roscopy on Biological Macromolecules L. Genzel, F. Kremer, A. Poglitsch, and G. Bechtold (With 10 Figures). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 Excitation of Proteins by Electric Fields J. B. Hasted, S. K. Husain, A. Y. Ko, D. Rosen, E. Nicol, and J. R. Birch (With 8 Figures) 71 Isotope Effects and Collective Excitations M. U. Palma (With 3 Figures) 84 Long-range Energy Continua in the Living Cell: Protochemical Considerations G. R. Welch and M. N. Berry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Coherent Excitations in Biological Systems
Author: H. Fröhlich
Publisher: Springer Science & Business Media
ISBN: 3642691862
Category : Medical
Languages : en
Pages : 234
Book Description
The articles in this volume are based on papers presented at the International Symposium in Bad Neuenahr November 29 - December 1, 1982. The meeting was directed by H. Frohlich and was sponsored by IBM Deutschland through its Science and Education Programs Department. Contents Coherence in Biology H. Frohlich . Coherent Excitations and Raman Effect F. Drissler and L. Santo (With 4 Figures) 6 The Non-thermal Effect of Millimeter Wave Radiation on the Puffing of Giant Chromosomes F. Kremer, C. Koschnitzke, L. Santo, P. Quick, and A. Poglitsch (With 4 Figures) 10 Nonthermal Resonant Effects of 42 GHz Microwaves on the Growth of Yeast Cultures W. Grundler, F. Keilmann, V. Putterlik, L. Santo, D. Strube, and I. Zimmermann (With 15 Figures) 21 On the Microwave Response of the Drosophila Melanogaster G. Nimtz (With 5 Figures) 38 Effects of Low-level Millimeter Waves on Cellular and Subcellular Systems S. M. Motzkin, L. Benes, N. Block, B. Israel, N. May, J. Kuriyel, L. Birenbaum, S. Rosenthal, and Q. Han (With 12 Figures). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 Millimeter-wave and Far-infrared Spec roscopy on Biological Macromolecules L. Genzel, F. Kremer, A. Poglitsch, and G. Bechtold (With 10 Figures). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 Excitation of Proteins by Electric Fields J. B. Hasted, S. K. Husain, A. Y. Ko, D. Rosen, E. Nicol, and J. R. Birch (With 8 Figures) 71 Isotope Effects and Collective Excitations M. U. Palma (With 3 Figures) 84 Long-range Energy Continua in the Living Cell: Protochemical Considerations G. R. Welch and M. N. Berry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Publisher: Springer Science & Business Media
ISBN: 3642691862
Category : Medical
Languages : en
Pages : 234
Book Description
The articles in this volume are based on papers presented at the International Symposium in Bad Neuenahr November 29 - December 1, 1982. The meeting was directed by H. Frohlich and was sponsored by IBM Deutschland through its Science and Education Programs Department. Contents Coherence in Biology H. Frohlich . Coherent Excitations and Raman Effect F. Drissler and L. Santo (With 4 Figures) 6 The Non-thermal Effect of Millimeter Wave Radiation on the Puffing of Giant Chromosomes F. Kremer, C. Koschnitzke, L. Santo, P. Quick, and A. Poglitsch (With 4 Figures) 10 Nonthermal Resonant Effects of 42 GHz Microwaves on the Growth of Yeast Cultures W. Grundler, F. Keilmann, V. Putterlik, L. Santo, D. Strube, and I. Zimmermann (With 15 Figures) 21 On the Microwave Response of the Drosophila Melanogaster G. Nimtz (With 5 Figures) 38 Effects of Low-level Millimeter Waves on Cellular and Subcellular Systems S. M. Motzkin, L. Benes, N. Block, B. Israel, N. May, J. Kuriyel, L. Birenbaum, S. Rosenthal, and Q. Han (With 12 Figures). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 Millimeter-wave and Far-infrared Spec roscopy on Biological Macromolecules L. Genzel, F. Kremer, A. Poglitsch, and G. Bechtold (With 10 Figures). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 Excitation of Proteins by Electric Fields J. B. Hasted, S. K. Husain, A. Y. Ko, D. Rosen, E. Nicol, and J. R. Birch (With 8 Figures) 71 Isotope Effects and Collective Excitations M. U. Palma (With 3 Figures) 84 Long-range Energy Continua in the Living Cell: Protochemical Considerations G. R. Welch and M. N. Berry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Beyond Born-Oppenheimer
Author: Michael Baer
Publisher: John Wiley & Sons
ISBN: 0471780073
Category : Science
Languages : en
Pages : 254
Book Description
INTRODUCING A POWERFUL APPROACH TO DEVELOPING RELIABLE QUANTUM MECHANICAL TREATMENTS OF A LARGE VARIETY OF PROCESSES IN MOLECULAR SYSTEMS. The Born-Oppenheimer approximation has been fundamental to calculation in molecular spectroscopy and molecular dynamics since the early days of quantum mechanics. This is despite well-established fact that it is often not valid due to conical intersections that give rise to strong nonadiabatic effects caused by singular nonadiabatic coupling terms (NACTs). In Beyond Born-Oppenheimer, Michael Baer, a leading authority on molecular scattering theory and electronic nonadiabatic processes, addresses this deficiency and introduces a rigorous approach--diabatization--for eliminating troublesome NACTs and deriving well-converged equations to treat the interactions within and between molecules. Concentrating on both the practical and theoretical aspects of electronic nonadiabatic transitions in molecules, Professor Baer uses a simple mathematical language to rigorously eliminate the singular NACTs and enable reliable calculations of spectroscopic and dynamical cross sections. He presents models of varying complexity to illustrate the validity of the theory and explores the significance of the study of NACTs and the relationship between molecular physics and other fields in physics, particularly electrodynamics. The first book of its king Beyond Born-Oppenheimer: * Presents a detailed mathematical framework to treat electronic NACTs and their conical intersections * Describes the Born-Oppenheimer treatment, including the concepts of adiabatic and diabatic frameworks * Introduces a field-theoretical approach to calculating NACTs, which offers an alternative to time-consuming ab initio procedures * Discusses various approximations for treating a large system of diabatic Schrödinger equations * Presents numerous exercises with solutions to further clarify the material being discussed Beyond Born-Oppenheimer is required reading for physicists, physical chemists, and all researchers involved in the quantum mechanical study of molecular systems.
Publisher: John Wiley & Sons
ISBN: 0471780073
Category : Science
Languages : en
Pages : 254
Book Description
INTRODUCING A POWERFUL APPROACH TO DEVELOPING RELIABLE QUANTUM MECHANICAL TREATMENTS OF A LARGE VARIETY OF PROCESSES IN MOLECULAR SYSTEMS. The Born-Oppenheimer approximation has been fundamental to calculation in molecular spectroscopy and molecular dynamics since the early days of quantum mechanics. This is despite well-established fact that it is often not valid due to conical intersections that give rise to strong nonadiabatic effects caused by singular nonadiabatic coupling terms (NACTs). In Beyond Born-Oppenheimer, Michael Baer, a leading authority on molecular scattering theory and electronic nonadiabatic processes, addresses this deficiency and introduces a rigorous approach--diabatization--for eliminating troublesome NACTs and deriving well-converged equations to treat the interactions within and between molecules. Concentrating on both the practical and theoretical aspects of electronic nonadiabatic transitions in molecules, Professor Baer uses a simple mathematical language to rigorously eliminate the singular NACTs and enable reliable calculations of spectroscopic and dynamical cross sections. He presents models of varying complexity to illustrate the validity of the theory and explores the significance of the study of NACTs and the relationship between molecular physics and other fields in physics, particularly electrodynamics. The first book of its king Beyond Born-Oppenheimer: * Presents a detailed mathematical framework to treat electronic NACTs and their conical intersections * Describes the Born-Oppenheimer treatment, including the concepts of adiabatic and diabatic frameworks * Introduces a field-theoretical approach to calculating NACTs, which offers an alternative to time-consuming ab initio procedures * Discusses various approximations for treating a large system of diabatic Schrödinger equations * Presents numerous exercises with solutions to further clarify the material being discussed Beyond Born-Oppenheimer is required reading for physicists, physical chemists, and all researchers involved in the quantum mechanical study of molecular systems.
Nonlinear Electrodynamics in Biological Systems
Author: W. Adey
Publisher: Springer Science & Business Media
ISBN: 146132789X
Category : Science
Languages : en
Pages : 589
Book Description
The past half century has seen an extraordinary growth in the fields of cellular and molecular biology. From simple morphologi cal concepts of cells as the essential units of living matter there has been an ever-sharper focus on functional organization of living systems, with emphasis on molecular dynamics. Thus, life forms have come to be defined increasingly in terms of metabolism, growth, reproduction and responses to environmental perturbations. Since these properties occur in varying degrees in systems below the level of cellular organization, there has been a blurring of older models that restricted the concepts of life to cellular systems. At the same time, a search has begun for elemental as pects of molecular and atomic behavior that might better define properties common to all life forms. This search has led to an examination of nonlinear behavior in biological macromolecules, whether in response to electrical or chemical stimulation, for example, or as a means of signaling along a molecular chain, or as a means of energy transfer. Experimental knowledge in this area has grown rapidly in the past decade, and in some respects has outstripped theoretical models adequate to ex plain these new observations. Nevertheless, it can be claimed that there is now an impressive body of experiments implicating non linear, nonequilibrium processes as fundamental steps in sequential operations of biological systems.
Publisher: Springer Science & Business Media
ISBN: 146132789X
Category : Science
Languages : en
Pages : 589
Book Description
The past half century has seen an extraordinary growth in the fields of cellular and molecular biology. From simple morphologi cal concepts of cells as the essential units of living matter there has been an ever-sharper focus on functional organization of living systems, with emphasis on molecular dynamics. Thus, life forms have come to be defined increasingly in terms of metabolism, growth, reproduction and responses to environmental perturbations. Since these properties occur in varying degrees in systems below the level of cellular organization, there has been a blurring of older models that restricted the concepts of life to cellular systems. At the same time, a search has begun for elemental as pects of molecular and atomic behavior that might better define properties common to all life forms. This search has led to an examination of nonlinear behavior in biological macromolecules, whether in response to electrical or chemical stimulation, for example, or as a means of signaling along a molecular chain, or as a means of energy transfer. Experimental knowledge in this area has grown rapidly in the past decade, and in some respects has outstripped theoretical models adequate to ex plain these new observations. Nevertheless, it can be claimed that there is now an impressive body of experiments implicating non linear, nonequilibrium processes as fundamental steps in sequential operations of biological systems.
Oxidative Stress and Redox Regulation
Author: Ursula Jakob
Publisher: Springer Science & Business Media
ISBN: 9400757875
Category : Science
Languages : en
Pages : 488
Book Description
Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.
Publisher: Springer Science & Business Media
ISBN: 9400757875
Category : Science
Languages : en
Pages : 488
Book Description
Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.
An Introduction To Plasmonics
Author: Olivier Pluchery
Publisher: World Scientific
ISBN: 1800613415
Category : Science
Languages : en
Pages : 356
Book Description
What is a plasmon? Is it a particle, like a photon or a wave? Plasmonics stands at the frontier of condensed matter physics, which is the world of electrons, optics and of photons. Plasmonics is one of the most active fields in nanophotonics. This book begins by exploring the concepts behind waves, and the electromagnetic description of light when it interacts with metals; it dedicates every chapter thereafter to all aspects of plasmonics. In particular, the surface plasmon polariton wave is explained in full detail, as well as the localized surface plasmon resonance of metallic nanoparticles. The active research area opened by plasmonics, as well as its applications, are also briefly explained, such as advanced biosensing, subwavelength waveguiding, quantum plasmonics, nanoparticle-based cancer therapies, optical nano-antenna and high-efficiency photovoltaic cells.The book is adapted for graduate students and places a special emphasis on providing complete explanations of the fundamental concepts of plasmonics. Further, each of these concepts is illustrated with examples drawn from the most recent scientific literature. Each chapter ends with a set of exercises that will help the reader revise the concepts and go deeper into the world of plasmonics. More than 70 exercises are included.
Publisher: World Scientific
ISBN: 1800613415
Category : Science
Languages : en
Pages : 356
Book Description
What is a plasmon? Is it a particle, like a photon or a wave? Plasmonics stands at the frontier of condensed matter physics, which is the world of electrons, optics and of photons. Plasmonics is one of the most active fields in nanophotonics. This book begins by exploring the concepts behind waves, and the electromagnetic description of light when it interacts with metals; it dedicates every chapter thereafter to all aspects of plasmonics. In particular, the surface plasmon polariton wave is explained in full detail, as well as the localized surface plasmon resonance of metallic nanoparticles. The active research area opened by plasmonics, as well as its applications, are also briefly explained, such as advanced biosensing, subwavelength waveguiding, quantum plasmonics, nanoparticle-based cancer therapies, optical nano-antenna and high-efficiency photovoltaic cells.The book is adapted for graduate students and places a special emphasis on providing complete explanations of the fundamental concepts of plasmonics. Further, each of these concepts is illustrated with examples drawn from the most recent scientific literature. Each chapter ends with a set of exercises that will help the reader revise the concepts and go deeper into the world of plasmonics. More than 70 exercises are included.
Silver in Organic Chemistry
Author: Michael Harmata
Publisher: John Wiley & Sons
ISBN: 1118057864
Category : Science
Languages : en
Pages : 395
Book Description
The first authoritative book on using silver cations in organic chemistry—for catalysis and more! With more sophisticated catalytic methodologies fueling a resurgence in the study of cation-based chemistry, gold and platinum have stepped to the fore as the unique agents used to create new chemical reactions. Although these metals have become a primary focus of researchers in the field, another coinage metal that is often overlooked—but is as powerful as the others—is silver, a far less costly alternative to gold and platinum in aiding the development of new reactions. Making a strong case for the use of silver as a catalyst and structural element in organometal constructs, this authoritative book is the first to explore the benefits of using silver in organic chemistry by taking a close look at silver’s unique reactivity and structural characteristics for the development of new methods and materials. Silver in Organic Chemistry is: The first book to address catalysis using silver, whose use in organic chemistry is on the verge of exploding A resource for researchers wishing to do chemistry with silver cations, an area that stands in the shadow of gold chemistry, but still glistens, demonstrating that all that glitters is not gold—sometimes it’s silver! A guide for “first attempts” in working with silver cations Edited by a very well-respected, highly visible authority in this field Silver in Organic Chemistry promotes further scientific discussion by offering important new ways to examine the future possibilities of an emerging field. By elevating the importance of silver chemistry, this thought-provoking guide illustrates how this versatile metal can become an increasingly significant player in opening the door to new catalytic organic reactions and new organometal materials.
Publisher: John Wiley & Sons
ISBN: 1118057864
Category : Science
Languages : en
Pages : 395
Book Description
The first authoritative book on using silver cations in organic chemistry—for catalysis and more! With more sophisticated catalytic methodologies fueling a resurgence in the study of cation-based chemistry, gold and platinum have stepped to the fore as the unique agents used to create new chemical reactions. Although these metals have become a primary focus of researchers in the field, another coinage metal that is often overlooked—but is as powerful as the others—is silver, a far less costly alternative to gold and platinum in aiding the development of new reactions. Making a strong case for the use of silver as a catalyst and structural element in organometal constructs, this authoritative book is the first to explore the benefits of using silver in organic chemistry by taking a close look at silver’s unique reactivity and structural characteristics for the development of new methods and materials. Silver in Organic Chemistry is: The first book to address catalysis using silver, whose use in organic chemistry is on the verge of exploding A resource for researchers wishing to do chemistry with silver cations, an area that stands in the shadow of gold chemistry, but still glistens, demonstrating that all that glitters is not gold—sometimes it’s silver! A guide for “first attempts” in working with silver cations Edited by a very well-respected, highly visible authority in this field Silver in Organic Chemistry promotes further scientific discussion by offering important new ways to examine the future possibilities of an emerging field. By elevating the importance of silver chemistry, this thought-provoking guide illustrates how this versatile metal can become an increasingly significant player in opening the door to new catalytic organic reactions and new organometal materials.
Chirality at the Nanoscale
Author: David B. Amabilino
Publisher: John Wiley & Sons
ISBN: 3527625356
Category : Technology & Engineering
Languages : en
Pages : 442
Book Description
The only standard reference in this exciting new field combines the physical, chemical and material science perspectives in a synergic way. This monograph traces the development of the preparative methods employed to create nanostructures, in addition to the experimental techniques used to characterize them, as well as some of the surprising physical effects. The chapters cover every category of material, from organic to coordination compounds, metals and composites, in zero, one, two and three dimensions. The book also reviews structural, chemical, optical, and other physical properties, finishing with a look at the future for chiral nanosystems.
Publisher: John Wiley & Sons
ISBN: 3527625356
Category : Technology & Engineering
Languages : en
Pages : 442
Book Description
The only standard reference in this exciting new field combines the physical, chemical and material science perspectives in a synergic way. This monograph traces the development of the preparative methods employed to create nanostructures, in addition to the experimental techniques used to characterize them, as well as some of the surprising physical effects. The chapters cover every category of material, from organic to coordination compounds, metals and composites, in zero, one, two and three dimensions. The book also reviews structural, chemical, optical, and other physical properties, finishing with a look at the future for chiral nanosystems.
Polymer-Protein Conjugates
Author: Gianfranco Pasut
Publisher: Elsevier
ISBN: 9780444640819
Category : Technology & Engineering
Languages : en
Pages : 0
Book Description
Polymer-Protein Conjugates: From Pegylation and Beyond helps researchers by offering a unique reference and guide into this fascinating area. Sections cover the challenges surrounding the homogeneity of conjugates, their purity and polymer toxicity on long-term use, and how to deal with the risk of immunogenicity. These discussions help researchers design new projects by taking into account the latest innovations for safe and site selective polymer conjugation to proteins. PEG has been the gold standard and likely will play this role for many years, but alternatives are coming into the market, some of which have already been launched. After five decades of improvements, the ideas in this book are entering into a new era of innovation because of the advances in genetic engineering, biochemistry and a better understanding of the results from clinical use of PEG conjugates in humans.
Publisher: Elsevier
ISBN: 9780444640819
Category : Technology & Engineering
Languages : en
Pages : 0
Book Description
Polymer-Protein Conjugates: From Pegylation and Beyond helps researchers by offering a unique reference and guide into this fascinating area. Sections cover the challenges surrounding the homogeneity of conjugates, their purity and polymer toxicity on long-term use, and how to deal with the risk of immunogenicity. These discussions help researchers design new projects by taking into account the latest innovations for safe and site selective polymer conjugation to proteins. PEG has been the gold standard and likely will play this role for many years, but alternatives are coming into the market, some of which have already been launched. After five decades of improvements, the ideas in this book are entering into a new era of innovation because of the advances in genetic engineering, biochemistry and a better understanding of the results from clinical use of PEG conjugates in humans.
Genome Duplication
Author: Melvin DePamphilis
Publisher: Garland Science
ISBN: 1136738231
Category : Science
Languages : en
Pages : 476
Book Description
Genome Duplication provides a comprehensive and readable overview of the underlying principles that govern genome duplication in all forms of life, from the simplest cell to the most complex multicellular organism. Using examples from the three domains of life - bacteria, archaea, and eukarya - Genome Duplication shows how all living organisms store their genome as DNA and how they all use the same evolutionary-conserved mechanism to duplicate it: semi-conservative DNA replication by the replication fork. The text shows how the replication fork determines where organisms begin genome duplication, how they produce a complete copy of their genome each time a cell divides, and how they link genome duplication to cell division. Genome Duplication explains how mistakes in genome duplication are associated with genetic disorders and cancer, and how understanding genome duplication, its regulation, and how the mechanisms differ between different forms of life, is critical to the understanding and treatment of human disease.
Publisher: Garland Science
ISBN: 1136738231
Category : Science
Languages : en
Pages : 476
Book Description
Genome Duplication provides a comprehensive and readable overview of the underlying principles that govern genome duplication in all forms of life, from the simplest cell to the most complex multicellular organism. Using examples from the three domains of life - bacteria, archaea, and eukarya - Genome Duplication shows how all living organisms store their genome as DNA and how they all use the same evolutionary-conserved mechanism to duplicate it: semi-conservative DNA replication by the replication fork. The text shows how the replication fork determines where organisms begin genome duplication, how they produce a complete copy of their genome each time a cell divides, and how they link genome duplication to cell division. Genome Duplication explains how mistakes in genome duplication are associated with genetic disorders and cancer, and how understanding genome duplication, its regulation, and how the mechanisms differ between different forms of life, is critical to the understanding and treatment of human disease.
Meat Hygiene
Author: J. F. Gracey
Publisher: Bailliere Tindall Limited
ISBN: 9780702022586
Category : Medical
Languages : en
Pages : 758
Book Description
Introducing the 10th Edition of this standard text covering all aspects of meat hygiene, from the production of clean and healthy animals, to the hygienic processing of meat and meat products, and the avoidance of food-borne hazards. This edition has been fully updated and revised to reflect a more integrated "farm to table" approach, and a more international perspective. Includes new material on BSE, a new section on operational hygiene, and more complete treatment of husbandry and ante-mortem issues.
Publisher: Bailliere Tindall Limited
ISBN: 9780702022586
Category : Medical
Languages : en
Pages : 758
Book Description
Introducing the 10th Edition of this standard text covering all aspects of meat hygiene, from the production of clean and healthy animals, to the hygienic processing of meat and meat products, and the avoidance of food-borne hazards. This edition has been fully updated and revised to reflect a more integrated "farm to table" approach, and a more international perspective. Includes new material on BSE, a new section on operational hygiene, and more complete treatment of husbandry and ante-mortem issues.