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Author: Corrado Tringali Publisher: CRC Press ISBN: 1439822298 Category : Science Languages : en Pages : 650
Book Description
The first edition of Bioactive Compounds from Natural Sources was published in a period of renewed attention to biologically active compounds of natural origin. This trend has continued and intensified—natural products are again under the spotlight, in particular for their possible pharmacological applications. Largely focusing on natural products as lead compounds in drug discovery, Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug Discovery is actually a completely new volume containing surveys of selected recent advances in an interdisciplinary area covering chemistry of natural products, medicinal chemistry, biochemistry, and other related topics. Written by some of the most reputed scientists in the field, this second edition includes new chapters from authors who contributed to the first edition as well as many chapters compiled by new authors. Introducing the reader to strategies and methods in the search for bioactive natural products, this book covers topics including: Natural sources of bioactive compounds such as aquatic cyanobacteria, filamentous fungi, and tropical plants, The tremendous potentiality of metabolic engineering of natural products biosynthesis The contribution of emerging or developing technologies to the study of bioactive natural compounds, namely computational methods and circular dichroism The potential of natural or natural-derived compounds for specific therapeutic applications: treatment of viral diseases, regulation of hypoxia-inducible factor, antimalarials, modulation of angiogenesis, and antitumor and wound-healing activity Selected examples of natural product families and related synthetic analogues, namely polyphenols and campthotecins Compiled for researchers and Ph.D. students working in interdisciplinary fields, this book will also be appreciated by readers without a background in chemistry interested in bioactive natural products, their biological and pharmacological properties, and their possible use as chemopreventive or chemotherapeutic agents. Conversely, the biological and pharmacological data and methods are accessible by chemists.
Author: Corrado Tringali Publisher: CRC Press ISBN: 1439822298 Category : Science Languages : en Pages : 650
Book Description
The first edition of Bioactive Compounds from Natural Sources was published in a period of renewed attention to biologically active compounds of natural origin. This trend has continued and intensified—natural products are again under the spotlight, in particular for their possible pharmacological applications. Largely focusing on natural products as lead compounds in drug discovery, Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug Discovery is actually a completely new volume containing surveys of selected recent advances in an interdisciplinary area covering chemistry of natural products, medicinal chemistry, biochemistry, and other related topics. Written by some of the most reputed scientists in the field, this second edition includes new chapters from authors who contributed to the first edition as well as many chapters compiled by new authors. Introducing the reader to strategies and methods in the search for bioactive natural products, this book covers topics including: Natural sources of bioactive compounds such as aquatic cyanobacteria, filamentous fungi, and tropical plants, The tremendous potentiality of metabolic engineering of natural products biosynthesis The contribution of emerging or developing technologies to the study of bioactive natural compounds, namely computational methods and circular dichroism The potential of natural or natural-derived compounds for specific therapeutic applications: treatment of viral diseases, regulation of hypoxia-inducible factor, antimalarials, modulation of angiogenesis, and antitumor and wound-healing activity Selected examples of natural product families and related synthetic analogues, namely polyphenols and campthotecins Compiled for researchers and Ph.D. students working in interdisciplinary fields, this book will also be appreciated by readers without a background in chemistry interested in bioactive natural products, their biological and pharmacological properties, and their possible use as chemopreventive or chemotherapeutic agents. Conversely, the biological and pharmacological data and methods are accessible by chemists.
Author: Samir K. Ballas Publisher: Lippincott Williams & Wilkins ISBN: 1496331834 Category : Medical Languages : en Pages : 1004
Book Description
Sickle Cell Pain is a panoramic, in-depth exploration of every scientific, human, and social dimension of this cruel disease. This comprehensive, definitive work is unique in that it is the only book devoted to sickle cell pain, as opposed to general aspects of the disease. The 752-page book links sickle cell pain to basic, clinical, and translational research, addressing various aspects of sickle pain from molecular biology to the psychosocial aspects of the disease. Supplemented with patient narratives, case studies, and visual art, Sickle Cell Pain’s scientific rigor extends through its discussion of analgesic pharmacology, including abuse-deterrent formulations. The book also addresses in great detail inequities in access to care, stereotyping and stigmatization of patients, the implications of rapidly evolving models of care, and recent legislation and litigation and their consequences.
Author: Ingolf Bernhardt Publisher: Springer Science & Business Media ISBN: 3662051818 Category : Science Languages : en Pages : 761
Book Description
51 worldwide leading experts in the field of erythrocyte research contributed to this first book on transport processes in red blood cells. It explains the latest findings on the basis of well-established principles, in an accessibly structured and carefully organized compilation.
Author: Paolo Annicchiarico Publisher: Food & Agriculture Org. ISBN: 9789251048702 Category : Science Languages : en Pages : 136
Book Description
The projected increase in world population levels and the subsequent rise in food demand represents a huge challenge for agricultural production systems worldwide. This publication examines the opportunities and challenges raised by the use of plant genetic resources and highlights the contribution that data from multi-environment yield trials can provide for the definition of adaptation strategies and yield stability targets in plant breeding programmes. It contains a case study about a durum wheat crop programme in Algeria, and also includes a CD-ROM with data from IRRISTAT, a programme developed by the International Rice Research Institute (IRRI).
Author: Phoebe A. Rice Publisher: Royal Society of Chemistry ISBN: 0854042725 Category : Science Languages : en Pages : 417
Book Description
This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.
Author: Chretien de Troyes Publisher: Yale University Press ISBN: 0300038380 Category : Poetry Languages : en Pages : 244
Book Description
A twelfth-century poem by the creator of the Arthurian romance describes the courageous exploits and triumphs of a brave lord who tries to win back his deserted wife's love
Book Description
Les protéines Myb sont des facteurs de transcription capables de contrôler la différentiation et la prolifération cellulaire. Il ne fait aujourd'hui aucun doute que les activités importantes des protéines Myb sont déterminées par leurs domaines fonctionnels. La spectroscopie RMN hétéronucléaire multidimensionnelle a été utilisée pour étudier le domaine de liaison minimale à l'ADN de la protéine v-Myb (R2R3 v-Myb) en phase aqueuse. Nous avons ainsi attribué la quasi-totalité de cette protéine. A l'aide des effets structurants secondaires, nous avons pu estimer les régions hélicoïdales de cette protéine. Comme pour toutes les protéines Myb étudiées structuralement jusqu'à présent, la répétition R3 de ce domaine présente effectivement trois hélices ? entre les résidus Glutamate 62 - Leucine 75, Tryptophane 79 - Lysine 84, Thréonine 91 - Sérine 100. Mais le domaine R2 de cette protéine semble avoir une structuration différente que celle déjà observées pour d'autres protéines Myb (C-Myb humain/poulet et B-Myb poulet). Ces protéines présentaient en effet une structuration en conformation multiple en partie C-Terminal de ce domaine alors que notre étude nous montre une structuration effective en hélice ? de cette région. Cette structuration avait déjà été observée pour la protéine C-Myb souris. La structuration de notre protéine se rapprocherait donc plus de celle mentionnée pour cette dernière. Il semble donc que la structure seule de ces protéines n'explique pas les différences d'activités biologiques observées pour v-Myb par rapport aux autres protéines Myb (notamment C-Myb souris).
Author: Juan Villalba Publisher: 5m Books Ltd ISBN: 1912178095 Category : Technology & Engineering Languages : en Pages : 212
Book Description
There has been a lot written about animal welfare in intensive farming systems, but very little about animals reared in extensive agricultural systems. Yet these animals make up a significant proportion of the world’s farm animal population, covering a large portion of the globe. Animals kept in extensive conditions face a unique set of challenges that are vital for anyone with an interest in farm animal welfare to understand. Animal Welfare in Extensive Production Systems presents those challenges in a practical way, backed up with thoroughly referenced research. Topics covered include heat stress, water quality and availability, nutrition, predation, poisonous plants, transport, human-animal interactions, and neonatal mortality. This book is ideal for animal welfare academics, students and researchers. It can also be beneficial to students in animal science, veterinary science and agriculture and to farm industry producers and personnel. The Animal Welfare Series covers current topics in animal welfare, to further research and inform the scientific, policy-making and farming communities. 5m Books
Author: M.D. Hayward Publisher: Springer ISBN: 0412433907 Category : Science Languages : en Pages : 550
Book Description
Our requirement for plant breeders to be successful has never been greater. However one views the forecasted numbers for future population growth we will need, in the immediate future, to be feeding, clothing and housing many more people than we do, inadequately, at present. Plant breeding represents the most valuable strategy in increasing our productivity in a way that is sustainable and environmentally sensitive. Plant breeding can rightly be considered as one of the oldest multidisciplinary subjects that is known to humans. It was practised by people who first started to carry out a settled form of agriculture. The art, as it must have been at that stage, was applied without any formal underlying framework, but achieved dramatic results, as witnessed by the forms of cultivated plants we have today. We are now learning how to apply successfully the results of yet imperfect scientific knowledge. This knowledge is, however, rapidly developing, particularly in areas of tissue culture, biotechnology and molecular biology. Plant breeding's inherent multifaceted nature means that alongside obvious subject areas like genetics we also need to consider areas such as: statistics, physiology, plant pathology, entomology, biochemistry, weed science, quality, seed characteristics, repro ductive biology, trial design, selection and computing. It therefore seems apparent that modern plant breeders need to have a grasp of wide range of scientific knowledge and expertise if they are successfully to a exploit the techniques, protocols and strategies which are open to them.
Author: Corrado Tringali
Author: Corrado Tringali
Author: Samir K. Ballas
Author: Ingolf Bernhardt
Author: Paolo Annicchiarico
Author: Phoebe A. Rice
Author: Chretien de Troyes
Author: Reynolds, M.P.
Author: Didier Rivière
Author: Juan Villalba
Author: M.D. Hayward