Ethnomedicine and Drug Discovery PDF Download

Author: M.M. Iwu
Publisher: Elsevier
ISBN: 0080531253
Category : Science
Languages : en
Pages : 347

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Approx.344 pages

Author: Muhammad Asif Hanif
Publisher: Elsevier
ISBN: 0081026609
Category : Science
Languages : en
Pages : 770

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Book Description
Medicinal Plants of South Asia: Novel Sources for Drug Discovery provides a comprehensive review of medicinal plants of this region, highlighting chemical components of high potential and applying the latest technology to reveal the underlying chemistry and active components of traditionally used medicinal plants. Drawing on the vast experience of its expert editors and authors, the book provides a contemporary guide source on these novel chemical structures, thus making it a useful resource for medicinal chemists, phytochemists, pharmaceutical scientists and everyone involved in the use, sales, discovery and development of drugs from natural sources. - Provides comprehensive reviews of 50 medicinal plants and their key properties - Examines the background and botany of each source before going on to discuss underlying phytochemistry and chemical compositions - Links phytochemical properties with pharmacological activities - Supports data with extensive laboratory studies of traditional medicines

Author: National Academy of Sciences/Smithsonian Institution
Publisher: National Academies Press
ISBN: 0309037395
Category : Science
Languages : en
Pages : 535

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Book Description
This important book for scientists and nonscientists alike calls attention to a most urgent global problem: the rapidly accelerating loss of plant and animal species to increasing human population pressure and the demands of economic development. Based on a major conference sponsored by the National Academy of Sciences and the Smithsonian Institution, Biodiversity creates a systematic framework for analyzing the problem and searching for possible solutions.

Author: Christophe Wiart
Publisher: Academic Press
ISBN: 0123983711
Category : Health & Fitness
Languages : en
Pages : 430

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Book Description
Kelley/DNA Repair in Cancer Therapy, 2012, 978-0-12-384999-1.

Author: Akhileshwar Kumar Srivastava
Publisher: Springer
ISBN: 9789819734047
Category : Science
Languages : en
Pages : 0

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Book Description
This book explains the translational aspects of ethnomedicinal plants of different geographical regions including India by explaining the medicinal properties against several diseases, genomic evolution in changing environments, metabolic profiling for biomarker discovery, the role of non-coding RNA in the synthesis of secondary metabolites, genome-wide transcriptome profiling, application of pluripotent stem cells for drug discovery, the importance of high-throughput omics, and genome-editing techniques. In addition, some of the chapters have been designed to describe the role of artificial intelligence, plant database, and network-based drug discovery to explore the medicinal importance of compounds as well as challenges and opportunities in drug discovery from ethnomedicinal plants. The book serves as a great source of information for the students, researchers/scientists of diverse fields such as pharmacognosy, plant physiologists, biotechnologists, and pharmaceutical scientists etc., working in the areas of phytotherapy from ethnomedicinal plants.

Author: Christophe Wiart
Publisher: Springer Science & Business Media
ISBN: 1597451606
Category : Medical
Languages : en
Pages : 236

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Book Description
In 1860, Oliver Wendell Holmes pointedly expressed himself to the Massachusetts Medical Society: “I firmly believe that if the whole Material Medica, as now used, could be sunk to the bottom of the sea, it would be all the better for mankind, and all the worst for the fishes.” Should one think the same about the current approach in drug discovery from plants? Probably yes. Despite the spending of billions of US dollars, and three decades of efforts, high-throughput screenings have only allowed the discovery of a couple of drugs. One could have reasonably expected the discovery of an arsenal of drugs from the millions of plant extracts randomly tested, but “hits” can be inactive in vitro or too toxic, some molecules need to be metabolized first to be active, and false-positive and false-negative results are common. The bitter truth is that the robotic approach in discovering drugs from plants has proven, to date, its inability to excavate the hundreds of molecules that will contribute to the health progress of Man. However, one can reasonably see that the last patches of primary rainforest on earth hold still hundreds of spectacularly active drugs that await discovery.

Author: Kishan Gopal Ramawat
Publisher: Springer Science & Business Media
ISBN: 354074603X
Category : Science
Languages : en
Pages : 391

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Book Description
This book on medicinal plant biotechnology covers recent developments in this field. It includes a comprehensive up-to-date survey on established medicinal plants and on molecules which gained importance in recent years. No recently published book has covered these carefully selected topics. The contributing scientists have been selected on the basis of their involvement in the related plant material as evident by their internationally recognised published work.

Author: Valdir Cechinel-Filho
Publisher: John Wiley & Sons
ISBN: 047058226X
Category : Science
Languages : en
Pages : 600

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Book Description
An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today. With coverage of strategic methods of natural compound isolation, structural manipulation, natural products in clinical trials, quality control, and more, and featuring case studies on medicinal plants, the book serves as a definitive guide to the field of plant biodiversity as it relates to medicine. In addition, chapters on using natural products as drugs that target specific disease areas, including neurological disorders, inflammation, infectious diseases, and cancer, illustrate the myriad possibilities for therapeutic applications. Wide ranging and comprehensive, Plant Bioactives and Drug Discovery also includes important information on marketing, regulations, intellectual property rights, and academic-industry collaboration as they relate to plant-based drug research, making it an essential resource for advanced students and academic and industry professionals working in biochemical, pharmaceutical, and related fields.

Author: Iqbal Ahmad
Publisher: John Wiley & Sons
ISBN: 3527609539
Category : Medical
Languages : en
Pages : 404

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Book Description
This timely and original handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the world demonstrate the potentials and pitfalls involved, with many of the studies and experiments reported here published for the first time. The result is a valuable source of information unavailable elsewhere.

Author: Ashish Tewari
Publisher: Elsevier
ISBN: 0081022743
Category : Science
Languages : en
Pages : 384

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Book Description
Synthesis of Medicinal Agents from Plants highlights the importance of synthesizing medicinal agents from plants and outlines methods for performing it effectively. Beginning with an introduction to the significance of medicinal plants, the book goes on to provide a historical overview of drug synthesis before exploring how this can be used to successfully replicate and adapt the active agents from natural sources. Chapters then explore the medicinal properties of a number of important plants, before concluding with a discussion of the future of drugs from medicinal plants. Illustrated with real-world examples, it is a practical resource for researchers in this field. In an age of rapid environmental destruction, hundreds of medicinal plants are at risk of extinction from overexploitation and deforestation, limiting the natural resources available for active agent extraction, thereby threatening the discovery of future cures for diseases. Simultaneously, with the increasing population and advances in medical sciences, the demand for drugs is continuously increasing and cannot be met with just plants. The ability to synthetically replicate the active compounds from these plants is essential in creating an ecologically-aware, sustainable future for drug design - Includes detailed coverage of therapeutic compound synthesis - Uses multiple real-world examples to support content - Lays out a sustainable template for the future of developing active agents from natural products