Estudio clínico de la asociación entre enfermedad periodontal y obesidad en pacientes con Síndrome de Down PDF Download

Author: Elena María Culebras Atienza
Publisher:
ISBN:
Category :
Languages : es
Pages : 174

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Author: Sandra Méndez Montero
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Category :
Languages : es
Pages :

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Author: Elisabeth Mauri Obradors
Publisher:
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Languages : es
Pages : 0

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"INTRODUCCIÓN: La periodontitis es una enfermedad infecciosa causada por bacterias anaeróbicas gram negativas, que pueblan la placa subgingival. Las principales bacterias involucradas son: Porphyromonas gingivalis, Prevotella intermedi y Actinomices Actinomicetacomytans. Grossi et al., en 1997 sugirieron que la infección crónica de bacterias gram negativas y la endotoxemia crónica, como la que vemos en la enfermedad periodontal, podría inducir a resistencia a la insulina y empeorar el control metabólico en diabéticos. Distintas investigaciones han demostrado que el raspado y alisado radicular (RAR), mejoran el estado periodontal en pacientes con diabetes. Estos estudios también observaron el efecto de dicho tratamiento en los niveles de la hemoglobina glicosilada (HbA1c). Una revisión realizada por nuestro equipo en 2014 mostró que la mayoría de estudios encuentran esta relación, sin embargo hacían faltan estudios más homogéneos, con muestras más grandes y períodos de seguimiento más largos. HIPÓTESIS Y OBJETIVOS: Esto nos llevó a plantear la hipótesis de nuestro estudio "¿Hay una disminución en los niveles de Hemoglobina Glicosilada en pacientes con DM2 en respuesta al tratamiento periodontal no quirúrgico?". El objetivo principal fue determinar la asociación entre el tratamiento periodontal no quirúrgico y la variación de HbA1c en pacientes con DM2. Además de conocer la asociación dicho tratamiento y la mejora de los parámetros periodontales así como la respuesta microbiológica en pacientes con DM2. MATERIAL Y MÉTODOS: El estudio fue aprobado por el comité de ética del Hospital Odontológico de la Universidad de Barcelona en Marzo de 2013 (Anexo 1). Se siguieron las guías CONSORT para ensayos clínicos. Se realizó un estudio clínico controlado aleatorizado paralelo entre dos muestras de pacientes que presentan DM2 y periodontitis crónica generalizada. El tamaño muestral fue de 90 pacientes, y la duración del estudio de 6 meses. Los criterios de inclusión fueron los siguientes: pacientes con DM2, Periodontitis crónica generalizada según el criterio propuesto por Armitage 1999. Se excluyeron los pacientes con que hayan tomado antibiótico los últimos 15 días, y/o tratamiento periodontal en los últimos 6 meses. Todos los pacientes fueron visitados tres veces (al inicio, a los 3 y a los 6 meses), y todas las visitas fueron supervisadas por la doctoranda en la misma clínica. El grupo de tratamiento recibió tratamiento periodontal no quirúrgico mediante RAR completo en una única sesión, e instrucciones de higiene oral. El grupo control (grupo de tratamiento mínimo) recibió profilaxis dental al inicio del estudio, e instrucciones de higiene oral. Se anotó el valor de HbA1c y la glucemia al inicio y al final del estudio. En la visita inicial, a los 3 y a los 6 meses se registraron los parámetros periodontales y se tomaron muestras sulculares para hacer el estudio microbiológico. RESULTADOS: Los resultados muestran una mejora significativa en los parámetros periodontales en el GT (p

Author: Junwei Yang
Publisher: Springer Nature
ISBN: 9813291311
Category : Medical
Languages : en
Pages : 253

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This book provides a comprehensive and systematic review of the latest findings in a wide spectrum of clinically important aspects of chronic kidney disease (CKD), focusing on clinical diagnosis and therapeutics. CKD is a global health problem with a rising morbidity and mortality. The last decade has seen significant improvements in determining the incidence, prevalence, and complications of CKD, mainly thanks to the definitions of CKD developed by the National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative (K/DOQI). However, increased recognition of CKD has led to awareness of the limitations of its clinical diagnosis and treatment, which are essential to patients’ wellbeing. This book is of particular value not only to nephrologists, but also to general practitioners and residents with an interest in CKD. It offers a well-organized exposition of the current knowledge base. Compared with previously published books on kidney disease and CKD, it has a smaller number of more concise chapters. As a result, readers can easily obtain an overview of the most important topics in CKD. We hope that practitioners will gain as much from reading this practical guide to clinical management of CKD as we have from editing it.

Author: Dolores Corella
Publisher: MDPI
ISBN: 3038429953
Category : Medical
Languages : en
Pages : 231

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This book is a printed edition of the Special Issue "Nutrigenetics" that was published in Nutrients

Author: Bernhard Baune
Publisher: Academic Press
ISBN: 0128110740
Category : Medical
Languages : en
Pages : 638

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Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. - Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry - Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system - Explores translational potential of targeting immune dysfunction for clinical interventions

Author: Irwin H. Rosenberg
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805573219
Category : Science
Languages : en
Pages : 266

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Humanity is aging. In the last century, life expectancy has increased by as much as 25 years, the greatest increase in 5'000 years of history. As a consequence the elderly constitute today the fastest growing segment of the world's population. This new situation creates many social problems and challenges to health care which both the developed as well as the developing countries will have to cope with. The present publication shows that scientific progress has reached a level where nutritional interventions may play a decisive part in the prevention of degenerative conditions of age, improvement of quality of life and impact on health care burden and resources. Topics deal with such different aspects as the influence of prenatal and early infant nutrition on the future aged individual and effects of energetic restriction on longevity. Further contributions include studies on mitochondrial alterations, digestive problems, specific metabolic deviations mediated by insulin, bone degradation, structural changes, neuromuscular dysfunctions, mental state of the elderly as well as the response of the immune system to nutrient intake. Finally the book offers a review of requirements appropriate to meet the age-related public health challenges of the 21st century.

Author: Kenneth H. Cooper
Publisher: Thomas Nelson
ISBN: 9780785278528
Category : Health & Fitness
Languages : en
Pages : 292

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Presents a program for revitalizing the body, mind, and spirit by restoring energy, vitality, and health and reversing many of the side effects of growing older.

Author: L. Kathleen Mahan
Publisher: Elsevier Health Sciences
ISBN: 1437722334
Category : Medical
Languages : en
Pages : 1255

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The most respected nutrition text for more than 50 years, Krause's Food & the Nutrition Care Process delivers comprehensive and up-to-date information from respected educators and practitioners in the field. The latest recommendations of the Dietary Guidelines for Americans 2010, new and expanded chapters, and a large variety of tables, boxes, and pathophysiology algorithms provide need-to-know information with ease, making this text perfect for use in class or everyday practice. Clear, logical organization details each step of complete nutritional care from assessment to therapy. UNIQUE! Pathophysiology algorithms clarify the illness process and to ensure more effective care. New Directions boxes reflect the latest research in emerging areas in nutrition therapy. Focus On boxes provide additional detail on key chapter concepts. Clinical Insight boxes and Clinical Scenarios with detailed Sample Nutrition Diagnosis statements help ensure the most accurate and effective interventions in practice. Key terms listed at the beginning of each chapter and bolded within the text provide quick access to important nutrition terminology. More than 1,000 self-assessment questions on a companion Evolve website reinforce key textbook content. Reorganized table of contents reinforces the Nutrition Care Process structure endorsed by the American Dietetic Association (ADA). New recommendations reflect a comprehensive approach to diet and nutrition that incorporates the Dietary Guidelines for Americans 2010, the MyPyramid food guide, and the Eating Well with Canada's Food Guide recommendations. MNT for Thyroid Disorders chapter details important nutrition considerations for managing thyroid disorders. New calcium and vitamin D Dietary Recommended Intakes (DRIs) improve monitoring of nutrient intake. Expanded Nutrition in Aging chapter includes assessment and nutritional care guidelines for the growing elderly patient population. Growth grids for children detail proper patient nutrition during infancy and early childhood. Extensively revised MNT for Food Allergies chapter highlights the importance of food allergy management in clinical nutrition therapy. Updated appendices enhance assessment accuracy with the latest laboratory findings and normal values.